Derivatives

Stictic acid, a depsidone in many lichen species, is a potentially bioactive compound. Derivatives of stictic acid were synthesised by halogenation or esterification. However, the effects of these conditions on the decomposition of stictic acid have yet to be studied. Hence, the modification of stictic acid was investigated using an AlCl3 catalyst and dimethylformamide solvent.

8p viaburame 14-03-2025 1 1   Download

A fragment-based approach has been applied to derive 2-(7-hydroxy-2-oxo-2H-chromen-4- yl)acetic acid 1 into 4 new coumarin derivatives 2a-d through amide bonds. The compounds were screened for their anticancer activity using MTT assay on MCF-7 and HepG2 cell lines.

10p viaburame 14-03-2025 0 0   Download

Ocimum africanum L. is a distinctive Vietnamese herb, especially common in Tuy Hòa, Phú Yên. This study focuses on extracting and analyzing the chemical composition of the essential oil derived from the leaves of Ocimum africanum. The essential oil was extracted using the steam distillation method and its chemical composition was analyzed using gas chromatography-mass spectrometry (GC-MS).

7p viaburame 14-03-2025 1 0   Download

The article presents a model and derives analytical expressions for Helmholtz free energy, the nearest neighbor distance, isothermal compressibility, the thermal expansion coefficient, the heat capacities at constant volume and constant pressure as functions of temperature, concentration of interstitial atoms, and film’s thickness for an interstitial binary alloy with a BCC structure based on the statistical moment method (SMM).

16p viaburame 14-03-2025 2 1   Download

Topical medications derived from traditional medicines play a crucial role in dermatological treatment, often serving as the primary therapeutic approach. The underlying causes of dermatological conditions may include external factors such as wind, cold, dampness, heat, parasites, or internal imbalances such as stagnation of qi, blood stasis or deficiencies in liver and kidney function. Treatment methods in traditional medicine may incorporate remedies, surgical interventions, or a combination of both.

6p tuongmotranh 18-03-2025 2 1   Download

To develop the Bio-pharmacology major at the university level, a comprehensive survey of invertebrate arthropods (Arthropoda) and annelids (Annelida) utilized as Vietnamese traditional medicines was conducted. The survey was organized according to six criteria: (1) Vietnamese and medicinal name, (2) classification and scientific name, (3) distribution and habitat, (4) medicinal properties, (5) pharmaceutical effects, (6) discussion and comments.

11p tuongmotranh 18-03-2025 1 1   Download

The projection, also called the symmetrization mapping, from spectral ball to symmetrized polydisc is closely related to the spectral Nevanlinna-Pick interpolation problem. We prove that the rank of the derivative of the projection from the spectral unit ball to the symmetrized polydisc is equal to the degree of the minimal polynomial of the matrix at which we take the derivative.

8p viaburame 14-03-2025 1 1   Download

In this paper, the problem of exponential stability of linear time-delay systems with mixed discrete and distributed delays is studied. Based on an asymmetric Lyapunov–Krasovskii functional approach, sufficient conditions are derived in terms of linear matrix inequalities to guarantee the exponential convergence of the system state trajectories with a prescribed decay rate.

14p viaburame 14-03-2025 6 1   Download

A benzothiazole ring plays an important role in pharmacological target diseases, including metabolic diseases, cancer, anti-inflammatory, neurodegeneration, viral diseases, bacterial infections, fibrosis, and thrombosis. Hydrazone-hydrazide derivatives are present in numerous biological molecules and play a significant role in medicine and pharmacology.

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In this work, the characterization of kaolin-based additives for the combustion of sugarcane bagasse-derived biomass was investigated using thermogravimetric-derivative thermogravimetric (TG-DTG) analysis and differential thermal analysis (DTA).

11p viaburame 14-03-2025 1 0   Download

In this study, we undertook the pyrochar from lemongrass essential oil distillation residue (LR) with incorporated alkali activation, scrutinizing its structural attributes, and assessing its efficacy in MB adsorption from aqueous solutions.

12p vifilm 11-10-2024 2 1   Download

In this paper, we propose an algorithm to discretize the n-th order derivative with high-order accuracy. Theoretical results and experimental calculations have confirmed the accuracy of the algorithm.

9p viling 11-10-2024 3 1   Download

In this study, 2D-QSAR analysis and molecular docking were performed to investigate the relationship between the hydroxamatebased HDAC inhibitors with benzimidazole scaffold and the activity toward HDAC6. A dataset of 55 N-hydroxybenzamide, Nhydroxypropenamide derivatives containing benzimidazole structure with HDAC6 in vitro activity were collected.

8p vihyuga 04-03-2025 2 1   Download

Acetylcholinesterase (AChE) has been one of the important and potential targets in the discovery, and development of new drugs for treating and slowing the progression of Alzheimer's disease (AD). This research suggests potential structural frameworks for synthesizing AChE inhibitor derivatives for treating AD.

11p vihyuga 04-03-2025 1 1   Download

Chamaecrista pumila has empirically been used to treat inflammation-associated complications. However, the molecular mechanism and chemical components underlying the anti-inflammatory activity of this medicinal plant are poorly understood. Hence, the present study aimed to identify main bioactive compounds from the ethyl acetate fraction of C. pumila extract, which was demonstrated to possess the strongest anti-inflammatory effect in a previous study, and provide mechanistic insights into modulation of inflammatory responses by the compound of interest.

13p vihyuga 04-03-2025 1 1   Download

Acetylcholinesterase (AChE) is a key therapeutic target for developing new Alzheimer's disease (AD) treatments due to its regulatory function in acetylcholine hydrolysis. This research contributed to the development of a novel scaffold for AChE inhibitors, which are potential drugs for treating AD.

17p vihyuga 04-03-2025 4 1   Download

In this study, heterogeneous catalysts were synthesized by hydrothermal method to load nano goethite to biochar derived from soybean curd residue, which served as catalysts for the heterogeneous degradation of tetracycline hydrochloride (TCH) in an aqueous solution.

9p viinuzuka 28-02-2025 3 1   Download

This paper presents methods for controlling a real model using the S7-400 controller with SCL language (Structured Control Language). The two controllers designed are the hybrid Neural Network Neural-PID (Proportional Integral Derivative) controller and the RBF (Radial Basis Function)- PID controller.

9p viyamanaka 06-02-2025 4 1   Download

This study compared the effects of convective hot air drying and freeze-drying on the quality and storage durability of protein powders made from salted egg whites. This investigation aims not only to close the identified knowledge gap but also to inform future practices in the sustainable manufacturing and storage of protein powders derived from salted egg whites.

8p viyamanaka 06-02-2025 2 2   Download

In this paper, by using q-difference analogue of the lemma on the logarithmic derivative and Nevanlinna theory for meromorphic functions in several variables, we study the proximity function of solutions to q-shift difference-partial differential.

8p tuetuebinhan000 23-01-2025 3 2   Download