Describe the family
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In this paper we describe some problems of the Romanian families in contemporary society: marital satisfaction, psychological and social implications of divorce and parental conflicts and the parental alienation syndrome.
7p christabelhuynh 04-06-2020 15 2 Download
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Giáo án unit 3 - English 6 mời bạn tham khảo. Giáo án sẽ giúp thầy cô hướng dẫn học sinh có thể mô tả những người trong gia đình , hỏi về tuổi tác, giới thiệu việc làm, đếm từ 1 - 100, đếm các mục trong phòng khách, hỏi và trả lời về các đối tượng số lượng.
19p hongtrang331 27-10-2013 105 12 Download
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In this study we describe the isolation of three genes of the CYP11B family of the guinea pig. CYP11B1 codes for the previously described 11b-hydroxylase [Bulow, H.E., Mobius, ¨ ¨ K., Bahr, V. & Bernhardt, R. (1996) Biochem. Biophys. Res. ¨ Commun. 221, 304–312] while CYP11B2 represents the aldosterone synthase gene. As no expression for CYP11B3 was detected this gene might represent a pseudogene.
9p system191 01-06-2013 39 3 Download
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The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec10 was identified through database mining of an asthmatic eosinophil EST library. Using the Stanford G3 radiation hybrid panel we were able to localize the genomic sequence of siglec-10 within the cluster of genes on chromosome 19q13.
14p system191 01-06-2013 43 6 Download
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We report the biochemical characterization of calhepatin, a calcium-binding protein of the S100 family, isolated from lungfish (Lepidosiren paradoxa) liver. The primary structure, determined by Edman degradation and MS/MS, shows that the sequence identities with the other members of the family are lower than those between S100 proteins from different species. Calhepatin is composed of 75 residues and has a molecular mass of 8670 Da. It is smaller than calbindin D9k (78 residues), the smallest S100 described so far....
9p research12 01-06-2013 44 4 Download
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Thefushi tarazu factor 1 (FTZ-F1) nuclear receptor sub-family comprises orphan receptors with crucial roles in development and sexual differentiation in vertebrates and invertebrates. We describe the structure and functional properties of an FTZ-F1 from the platyhelminth parasite of humans,Schistosoma mansoni, the first receptor from this family tobe characterized inaLophotrochozoan. It contains awell conservedDNA-binding domain (55–63%identity to other family members) and a poorly conserved ligand-binding domain (20% identity to that of zebrafish FF1a)....
12p tumor12 22-04-2013 46 2 Download
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Sequence analysis of aPaenibacillussp. BP-23 recombinant clone coding for a previously described endoglucanase revealed the presence of an additional truncated ORF with homology to family 48 glycosyl hydrolases. The corres-ponding 3509-bp DNA fragment was isolated after gene walking and cloned inEscherichia coliXl1-Blue for expres-sion and purification. The encoded enzyme, a cellulase of 1091 amino acids with a deduced molecular mass of 118 kDa and a pI of 4.
7p fptmusic 16-04-2013 50 3 Download
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The folding of a 93-residue protein, the histidine-phospho-carrier protein ofStreptomyces coelicolor,HPr,hasbeen studied using several biophysical techniques, namely fluo-rescence, 8-anilinonaphthalene-1-sulfate binding, circular dichroism, Fourier transform infrared spectroscopy, gel filtration chromatography and differential scanning calori-metry. The chemical-denaturation behaviour of HPr, fol-lowed by fluorescence, CD and gel filtration, at pH 7.5 and 25C, is described as a two-state process, which does not involve the accumulation of thermodynamically stable intermediates.
14p fptmusic 16-04-2013 55 4 Download
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Much of the basic biochemistry of antiplasmin was described more than 20 years ago and yet it remains an enigmatic member of the serine protease inhibitor (serpin) family. It possesses all of the characteristics of other inhibitory serpins but in addition it has unique N- and C-terminal exten-sions which significantly modify its activities. The N-terminus serves as a substrate for Factor XIIIa leading to crosslinking and incorporation of antiplasmin into a clot as it is formed.
6p fptmusic 12-04-2013 29 2 Download
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Báo cáo khoa học: Adhesion properties of adhesion-regulating molecule 1 protein on endothelial cells
Numerous adhesion molecules have been described, and the molecular mechanisms of lymphocyte trafficking across the endothelium is starting to be elucidated. Identification of the molecules involved in the organoselec-tivity of this process would help in the targeting of drug therapy to specific tissues. Adhesion-regulating molecule-1 (ARM-1) is an adhesion-regulating molecule previously identified on T cells. It does not belong to any known families of adhesion molecules.
12p awards 06-04-2013 35 4 Download
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This work presents a computational analysis of the molecular characteris-tics shared by the adenylation domains from traditional nonribosomal pep-tide synthetases (NRPSs) and the group of the freestanding homologous enzymes: a-aminoadipate semialdehyde dehydrogenase, a-aminoadipate reductase and the protein Ebony. The results of systematic sequence com-parisons allow us to conclude that a specificity-conferring code, similar to that described for the NRPSs, can be recognized in such enzymes.
13p awards 05-04-2013 34 3 Download
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The cloning of two novel genes that encode cytokinin oxidase/dehydrogenase (CKX) in barley is described in this work. Transformation of both genes intoArabidopsisand tobacco showed that at least one of the genes codes for a functional enzyme, as its expression caused a cytokinin-deficient phenotype in the heterologous host plants. Addi-tional cloning of two gene fragments, and anin silicosearch in the public expressed sequence tag clone databases, revealed the presence of at least 13 more members of the CKXgene family in barley and wheat. ...
13p awards 05-04-2013 54 4 Download
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We describe a strategy for systematic amplification of chitin synthase genes (chs) in the filamentous ascomycetes plant-pathogenBotrytis cinereausing PCR with multiple degen-erate primers designed on specific and conserved sequence motifs. Eight distinctchsgeneswere isolated, namedBcchs I, II, IIIa, IIIb, IV, V, VIandVII. They probably constitute the entire chsmultigenic family of this fungus, as revealed by careful analysis of six euascomycetes genomes.
12p dell39 03-04-2013 37 4 Download
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Genomic sequencing of the methanotrophic bacterium,Methylococcus cap-sulatus (Bath), revealed an open reading frame (MCA2590) immediately upstream of the previously described mopEgene (MCA2589). Sequence analyses of the deduced amino acid sequence demonstrated that the MCA2590-encoded protein shared significant, but restricted, sequence simi-larity to the bacterial di-heme cytochrome c peroxidase (BCCP) family of proteins.
12p dell39 27-03-2013 40 3 Download
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Recently, cupin type phosphoglucose isomerases have been described as a novel protein family representing a separate lineage in the evolution of phosphoglucose isomerases. The importance of eight active site residues completely conserved within the cPGI family has been assessed by site-directed mutagenesis using the cPGI fromArchaeoglobus fulgidus(AfcPGI) as a model.
10p dell39 27-03-2013 46 4 Download
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Thepcd1mutant of pea lacks heme oxygenase (HO) activity required for the synthesis of the phytochrome chromophore and is consequently severely deficient in all responses mediated by the phytochrome family of plant photoreceptors. Here we describe the isolation of the gene encoding pea heme oxygenase 1 (PsHO1) and confirm the presence of a mutation in this gene in the pcd1 mutant.
13p inspiron33 26-03-2013 55 4 Download
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The peptides of the neuropeptide Y (NPY) family exert their functions, including regulation of appetite and circadian rhythm, by binding to G-protein coupled receptors. Mammals have five subtypes, named Y1,Y2 , Y4,Y5 and Y6, and recently Y7 has been discovered in fish and amphibi-ans. In chicken we have previously characterized the first four subtypes and here we describe Y6 and Y7.
16p inspiron33 26-03-2013 34 4 Download
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All eukaryotic topoisomerase I enzymes are monomeric enzymes, whereas the kinetoplastid family (TrypanosomaandLeishmania) possess an unusual bisubunit topoisomerase I. To determine what happens to the enzyme architecture and catalytic property if the two subunits are fused, and to explore the functional relationship between the two subunits, we describe herein vitro gene fusion of Leishmaniabisubunit topoisomerase I into a single ORF encoding a new monomeric topoisomerase I (LdTOPIL-fus-S).
14p inspiron33 23-03-2013 36 4 Download
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The crustacean hyperglycemic hormone (CHH) plays an important role in the regulation of hemolymph glucose levels, but it is also involved in other functions such as growth, molting and reproduction. In the present study we describe the first CHH family gene isolated from the Atlantic Ocean shrimp Litopenaeus schmitti.
9p inspiron33 23-03-2013 43 4 Download
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LeIF, aLeishmaniaprotein similar to the eukaryotic initiation factor eIF4A, which is a prototype of the DEAD box protein family, was origin-ally described as a Th1-type natural adjuvant and as an antigen that indu-ces an IL12-mediated Th1 response in the peripheral blood mononuclear cells of leishmaniasis patients.
15p inspiron33 23-03-2013 32 3 Download