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Diseases including cancer
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In recent years, there has been an increase in the incidence and mortality rates of prostate cancer (PCa). However, the specific molecular mechanisms underlying its occurrence and development remain unclear, necessitating the identification of new therapeutic targets.
10p
vishanshan
27-06-2024
2
1
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The objective of this study was to describe real-world adjuvant therapy (AT) use by disease substage and assess determinants of treatment choice among patients with stage III melanoma. This non-interventional retrospective study included survey responses and data from patient records pro‑ vided by US medical oncologists.
13p
vishanshan
27-06-2024
2
1
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Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival.
12p
vishanshan
27-06-2024
1
1
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Astragaloside IV (AS-IV) is one of the basic components of Astragali radix, that has been shown to have preventive effects against various diseases, including cancers. This study aimed to explore the role of AS-IV in hepatocellular carcinoma (HCC) and its underlying mechanism.
13p
vikoch
27-06-2024
1
1
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Screening of cancer is the maximum effort and critical element for providing health related care in order to decrease cancer related dealt because of the disease burden is in its advanced stages. Unfortunately, advanced-stage presentation and late diagnosis of cancers endure a problem in low-income countries including Ethiopia. However, there is scarcity of published articles about the problem in Ethiopia.
8p
vikoch
27-06-2024
1
1
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Poor oral health has been linked to various systemic diseases, including multiple cancer types, but studies of its association with lung cancer have been inconclusive. Methods We examined the relationship between dental status and lung cancer incidence and mortality in the Golestan Cohort Study, a large, prospective cohort of 50,045 adults in northeastern Iran.
9p
vikoch
27-06-2024
2
1
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Testicular germ cell tumours (TGCTs) are the most common malignancy in men aged 15–40 years, with increasing incidence worldwide. About 33~50% of the patients present with metastatic disease at diagnosis. TGCT survivors experience short- and long-term sequelae, including cancer-related fatigue (CRF).
15p
vikoch
27-06-2024
2
1
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This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases.
363p
vimeyers
29-05-2024
2
2
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Part 2 book "Clinical surgery in general" includes content: Adjuncts to surgeryl; prevention of infection in surgical practice; the risks to surgeons of nosocomial virus transmission, good surgical practice, minimal access surgery, principles of skin cover, pathogenesis of cancer, principles of surgery for malignant disease, principles of radiotherapy.
299p
zizaybay1101
30-04-2024
9
2
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Ebook "Complement therapeutics" highlights progress and trends in the rapidly evolving field of complement-related drug discovery and spotlights examples of clinical applications. As an integral part of innate immunity and critical mediator in homeostatic and inflammatory processes, the human complement system has been identified as contributor to a large number of disorders including ocular, cardiovascular, metabolic, autoimmune, and inflammatory diseases as well as in ischemia/reperfusion injury, cancer and sepsis.
323p
ladongphongthanh1008
22-04-2024
3
3
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Ebook "Cell and molecular biology of breast cancer" is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research.
382p
ladongphongthanh1008
22-04-2024
7
1
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Part 2 book "Fundamentals and applications of controlled release drug delivery" includes content: Targeted delivery using biodegradable polymeric nanoparticles; liposomes in drug delivery; receptor mediated delivery systems for cancer therapeutics, biological rhythms, drug delivery, and chronotherapeutics; site specific controlled release for cardiovascular disease - translational directions; drug delivery systems to fight cancer; fundamentals of vaccine delivery in infectious diseases; tissue engineering in drug delivery.
340p
muasambanhan10
03-04-2024
1
0
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Part 2 book "Oral medicine and pathology - A guide to diagnosis and management" includes content: Potentially malignant disorders, oral cancer, recurrent oral ulceration, vesiculobullous disorders, infections of the oral mucosa, connective tissue diseases, chronic facial pain, emporomandibular joint disorders, oral manifestations of systemic disease,... and other contents.
295p
muasambanhan10
06-04-2024
2
0
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Part 1 book "Textbook of oral medicine, oral diagnosis and oral radiology" includes content: History and scope of oral medicine and oral radiology; developmental disturbances; orofacial pigmentation disorders; bacterial, viral and fungal infections; orofacial pain, red and white lesions; vesiculobullous disorders; oral ulcerative diseases; dermatological diseases, temporomandibular disorders; diseases of salivary glands, cysts of orofacial region; tumors of orofacial region; oral cancer.
429p
muasambanhan10
06-04-2024
6
2
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Accumulating evidence suggests alternative splicing (AS) is a co-transcriptional splicing process not only controlled by RNA-binding splicing factors, but also mediated by epigenetic regulators, such as chromatin structure, nucleosome density, and histone modification. Aberrant AS plays an important role in regulating various diseases, including cancers.
11p
vibransone
28-03-2024
5
2
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Clinical whole-genome sequencing (WGS) offers clear diagnostic benefits for patients with rare disease. However, there are barriers to its widespread adoption, including a lack of standards for clinical practice. The Medical Genome Initiative consortium was formed to provide practical guidance and support the development of standards for the use of clinical WGS.
4p
vibransone
28-03-2024
4
2
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Hutchinson-Gilford progeria syndrome (HGPS) is a progeroid disease characterized by the early onset of age-related phenotypes including arthritis, loss of body fat and hair, and atherosclerosis. Cells from affected individuals express a mutant version of the nuclear envelope protein lamin A (termed progerin) and have previously been shown to exhibit prominent histone modification changes.
16p
vibransone
28-03-2024
3
2
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Angiosarcoma is an aggressive tumor. Recent case series describe exceptional responses to checkpoint blockade in this disease. Methods: Herein, we explored the genomic correlates of 48 angiosarcomas from the Angiosarcoma Project (12,499 variants analyzed in 6603 genes; whole-exome sequencing) versus 10,106 pan-cancer tumors in The Cancer Genome Atlas including 235 sarcomas but no angiosarcoma.
6p
vibransone
28-03-2024
4
2
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A challenge in the post-GWAS era is to assign function to disease-associated variants. However, available resources do not include all tissues or environmental exposures that are relevant to all diseases. For example, exaggerated bronchoconstriction of airway smooth muscle cells (ASMCs) defines airway hyperresponsiveness (AHR), a cardinal feature of asthma.
14p
vibransone
28-03-2024
9
2
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Epigenetic alterations are associated with normal biological processes such as aging or differentiation. Changes in global epigenetic signatures, together with genetic alterations, are driving events in several diseases including cancer. Comparative studies of cancer and healthy tissues found alterations in patterns of DNA methylation, histone posttranslational modifications, and changes in chromatin accessibility.
12p
vibransone
28-03-2024
7
2
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