Division of pathology

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  • Welcome to the home of the online edition of The Cancer Handbook which provides a comprehensive overview of all major areas of cancer research and oncology. This title differs from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. ...

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  • Useful as it is however, the NCI Metathesaurus is not well suited to serve as a coding nomenclature1 . The hierarchies of the NCI terminology in NCI Metathesaurus are not true IS_A hierarchies, for example. The NCI Thésaurus, which became operational in late 2001, is designed to address this need. It is intended for NCI offices and divisions to use the Thésaurus as a source of codes associated with terminology concepts to annotate data and other information artifacts and facilitate information retrieval.

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  • Ever since the time of Hippocrates attempts have been made to classify tuberculosis. Not until the 19th century was a clear clinical division made between acute and chronic forms (Fournet, 1839); later there was a tendency to describe these forms as ‘galloping consumption’ and ‘consumption’; to-day they can be accurately described, not only on clinical grounds, but pathologically, radiologically and pathogenetically as ‘malig nant primary’ and ‘advance secondary’. The first clinico-pathological classification was by Bard (1898, 1927).

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