DNA molecules

Ebook "DNA helicases and DNA motor proteins" is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

308p ladongphongthanh1008 22-04-2024 4 2   Download

Ebook "Biophysics of DNA-protein interactions: From single molecules to biological systems" would focus on the specific topic of the biophysics of DNA-protein interactions, and would include the use of new approaches, including both bulk methods as well as single molecule methods. This would make the book attractive to anyone working in the general area of DNA-protein interactions, which is of course a much wider market than just single molecule biophysicists or even biophysicists.

354p ladongphongthanh1008 22-04-2024 8 2   Download

Ebook "Advancing development of synthetic gene regulators: With the power of high-throughput sequencing in chemical biology" focuses on an “outside the box” notion by utilizing the powerful applications of next-generation sequencing (NGS) technologies in the interface of chemistry and biology. In personalized medicine, developing small molecules targeting a specific genomic sequence is an attractive goal. N-methylpyrrole (P)–N-methylimidazole (I) polyamides (PIPs) are a class of small molecule that can bind to the DNA minor groove.

123p tracanhphuonghoa1007 22-04-2024 6 2   Download

Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for detecting and characterizing diseases such as cancer. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This approach generated up to 200 million reads for a single cfDNA sample from cancer patients, an order of magnitude improvement over existing nanopore sequencing methods.

13p vicwell 29-02-2024 2 1   Download

Ebook "Energy transfer dynamics in biomaterial systems (Springer series in chemical physics, Volume 93)" summarizes recent progress in this direction, focusing on the role of quantum dynamical phenomena in biological and nanostructured systems. The book grew out of a workshop that was held in October 2007 in Paris on the topic of “Energy flow dynamics in biomaterial systems”.

479p manmanthanhla0201 26-02-2024 5 1   Download

Ebook "Fluorescence spectroscopy in biology: Advanced methods and their applications to membranes, proteins, dna, and cells" focuses on two new approaches in cell fluorescence microscopy. R. Brock shows how to characterize diffusion in cells by fluorescence correlation spectroscopy. The last two contributions by S. Rosenthal and O. Minet are devoted to photophysics and the use of quantum dots in cell imaging.

315p manmanthanhla0201 27-02-2024 3 2   Download

Ebook "Aptamers selected by Cell-SELEX for theranostics" as the fundamental tool used to generate aptamer molecules for a wide range of applications in molecular medicine, bioanalysis and chemical biology. Easily integrated into the natural heterogeneous cell matrix, aptamers can be effectively used in theranostics, bioanalysis, environment detection and biomedical studies.

352p nhanphanguyet 28-01-2024 2 2   Download

In ebook "Artificially controllable nanodevices constructed by DNA origami technology: Photofunctionalization and single-molecule analysis" the author deals mainly with two topics: (1) single-molecule visualization of switching behaviors in the DNA nanoframe system utilizing different kinds of molecular switches through the use of high-speed atomic force microscope (AFM); (2) construction of photocontrollable DNA nanostructures in programmed patterns and direct visualization of the dynamic assembling process.

82p nhanphanguyet 28-01-2024 3 2   Download

Ebook "Single molecule analysis: Methods and protocols (Second edition)" is to provide a broad overview of single-molecule approaches applied to biomolecules. Chapters in Single Molecule Techniques: Methods and Protocols, Second Edition detail the most widely used single-molecule techniques, such as DNA, DNA-binding proteins, motor proteins, and are becoming commonplace in molecular biophysics, biochemistry, and molecular and cell biology.

369p lucchinguyen 28-12-2023 4 2   Download

Part 1 book "Reproductive endocrinology" includes content: Introduction to the molecular organization of the endocrine reproductive system; extracellular signaling receptors; the molecules that transmit information into the cell - the intracellular signaling pathways; introduction to molecular biology - structure and function of the macromoleculesof genetic information; regulation of gene expression; molecular basis of abnormal phenotype; recombinant DNA technology,... and other contents.

159p muasambanhan03 25-12-2023 1 1   Download

The consequences of weaponizing universal reactions of matter have very dangerous enhancing effects on human genomic diseases. In fact, utilizing weapons of universal reactions of matter in war can delete all forms of genomic-things including humans, all material wealth, science and technology we have from the surface of this planet within few hours.

14p vikissinger 21-12-2023 3 1   Download

Part 1 book "Essentials of biology" includes content: The chemical basis of life, the organic molecules of life, inside the cell; the dynamic cell, energy for life, energy for cells, cellular reproduction, meiosis and the genetic basis of sexual reproduction, patterns of inheritance, DNA biology, biotechnology and genomics, genetic counseling,.... and other contents.

390p oursky07 23-10-2023 12 3   Download

Although a long-term goal of cancer therapy always has been the development of agents that selectively destroy cancer cells, more recent trends have been to seek secondary agents that sensitize cancer cells to existing treatment regimens.

13p vioracle 29-09-2023 8 3   Download

Ebook Principles of biochemistry (8th edition): Part 3 includes content: Lipid biosynthesis; biosynthesis of amino acids, nucleotides, and related molecules; hormonal regulation and integration of mammalian metabolism III information pathways; genes and chromosomes; DNA metabolism, RNA metabolism; protein metabolism; regulation of gene expression.

1736p oursky05 20-09-2023 5 2   Download

Part 1 book "Molecular biology of the cell" includes content: Cells and genomes; cell chemistry and bioenergetics; proteins DNA, chromosomes, and genomes; DNA, replication, repair, and recombination; how cells read the genome - from DNA to protein; control of gene expression; analyzing cells, molecules, and systems; visualizing cells.

599p oursky02 06-08-2023 6 3   Download

Hypomethylation of long interspersed nuclear element 1 (LINE-1) is characteristic of various cancer types, including colorectal cancer (CRC). Malfunction of several factors or alteration of methyl-donor molecules’ (folic acid and S-adenosylmethionine) availability can contribute to DNA methylation changes.

11p visusanwojcicki 28-06-2022 10 2   Download

Conventional techniques for single-base resolution mapping of epigenetic modifications of DNA such as 5-hydroxymethylcytosine (5hmC) rely on the sequencing of bisulfite-modified DNA. Here we present an alternative approach called SCL-exo which combines selective chemical labeling (SCL) of 5hmC in genomic DNA with exonuclease (exo) digestion of the bead-trapped modified DNA molecules.

12p viaristotle 29-01-2022 15 0   Download

There is no effective way to detect structure variations (SVs) and extra-chromosomal circular DNAs (ecDNAs) at single-cell whole-genome level. Here, we develop a novel third-generation sequencing platform-based single-cell whole-genome sequencing (scWGS) method named SMOOTH-seq (single-molecule real-time sequencing of long fragments amplified through transposon insertion).

19p viarchimedes 26-01-2022 14 0   Download

Nanopore long-read sequencing technology greatly expands the capacity of long-range, single-molecule DNA-modification detection. A growing number of analytical tools have been developed to detect DNA methylation from nanopore sequencing reads.

33p viarchimedes 26-01-2022 11 0   Download

Quantifying the genetic heterogeneity of a cell population is essential to understanding of biological systems. We develop a universal method to label individual DNA molecules for single-base-resolution haplotype-resolved quantitative characterization of diverse types of rare variants, with frequency as low as 4 × 10−5 , using both short- or long-read sequencing platforms.

14p viarchimedes 26-01-2022 6 0   Download