Domain specific drug targets

Part 2 book "Apicomplexan parasites - Molecular approaches toward targeted drug development" includes content: Novel apicomplexan phosphatases and immunophilins as domain specific drug targets, dehydrogenases and enzymes of the mitochondrial electron transport chain as anti apicomplexan drug targets; drugs and drug targets in neospora caninum and related apicomplexans, current aspects of endoperoxides in antiparasitic chemotherapy, drug discovery against babesia and toxoplasma,.... and other contents.

269p oursky04 14-09-2023 6 3   Download

Regulator of G-protein signaling (RGS) proteins were originally identified as negative regulators of G-protein-coupled receptor (GPCR) signaling via their GTPase-accelerating protein (GAP) activity. All RGS proteins contain evolutionarily conserved RGS domain; however, they differ in their size and regulatory domains. RGS1 and RGS10 are smaller than other RGS proteins, and their functions involve various inflammatory responses including autoimmune responses in both the periphery and the central nervous system (CNS). Neuroinflammation is the chronic inflammatory response in the CNS.

5p caothientrangnguyen 09-05-2020 22 1   Download