Dramatic references

Breast cancer is an umbrella term referring to a group of biologically and molecularly heterogeneous diseases originating from the breast. Globally, incidences of breast cancer has been increasing dramatically over the past decades.

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The rapid development of Next-Generation Sequencing technologies enables sequencing genomes with low cost. The dramatically increasing amount of sequencing data raised crucial needs for efficient compression algorithms.

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Due to advances in hip arthroscopy, the number of surgical procedures has increased dramatically. The diagnostic challenge in patients with longstanding hip and groin pain, as well as the increasing number of hip arthroscopies, may lead to a higher number of patients referred to tertiary care for consideration for surgery.

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Jingoism is extreme patriotism in the form of aggressive foreign policy. In practice, it is a country's advocacy of the use of threats or actual force against other countries in order to safeguard what it perceives as its national interests. Colloquially, it refers to excessive bias in judging one's own country as superior to others—an extreme type of nationalism.

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This chapter presents the following content: Analytical Mapping: Social Significance; philosophical background: themes (Social, Psychological, Religious); dramatic references: themes.

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There is never any overt reference in the play to Pygmalion; Shaw assumes a classical understanding. According to the Mythology Guide “Pygmalion saw so much to blame in women that he came at last to abhor the relation with them, and resolved to live unmarried. He was a sculptor, and had made with wonderful skill a statue of ivory, so beautiful that no living woman could be compared to it in beauty.

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This chapter presents the following content: Plot overview, genre, general vision, cultural context, the play as reflection of social and personal influences, the play’s title vs. context: reference and relevance, themes/issues.

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The rapid progress of high-throughput DNA sequencing techniques has dramatically reduced the costs of whole genome sequencing, which leads to revolutionary advances in gene industry. The explosively increasing volume of raw data outpaces the decreasing disk cost and the storage of huge sequencing data has become a bottleneck of downstream analyses.

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Chemotherapy via oral route of anticancer drugs offers much convenience and compliance to patients. However, oral chemotherapy has been challenged by limited absorption due to poor drug solubility and intestinal efflux. In this study, we aimed to develop a nanosuspension formulation of oridonin (Odn) using its cyclodextrin inclusion complexes to enhance oral bioavailability. Nanosuspensions containing Odn/2 hydroxypropyl-β-cyclodextrin inclusion complexes (Odn-CICs) were prepared by a solvent evaporation followed by wet media milling technique.

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The Six Sigma Handbook, Third edition is the only comprehensive reference you need to make Six Sigma work for your company. The book explains how to organize for Six Sigma, how to use customer requirements to drive strategy and operations, how to carry out successful project management, and more.

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An approach to abductive inference developed in the TACITUS project has resulted in a dramatic simplification of how the problem of interpreting texts is conceptualized. Its use in solving the local pragmatics problems of reference, compound nominals, syntactic ambiguity, and metonymy is described and illustrated. It also suggests an elegant and thorough integration of syntax, semantics, and pragmatics.

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What can you do when database performance doesn't meet expectations? Before you turn to expensive hardware upgrades to solve the problem, reach for this book. Refactoring SQL Applications provides a set of tested options for making code modifications to dramatically improve the way your database applications function. Backed by real-world examples, you'll find quick fixes for simple problems, in-depth answers for more complex situations, and complete solutions for applications with extensive problems....

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We will refer to embeddings providing a guarantee akin to that of Lemma 1.1 as JL- embeddings. In the last few years, such embeddings have been used in solving a variety of problems. The idea is as follows. By providing a low-dimensional representation of the data, JL-embeddings speed up certain algorithms dramatically, in particular algorithms whose run-time depends exponentially in the dimension of the working space. (For a number of practical problems the best-known algorithms indeed have such behavior.

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A major shift in the perception of the fundamentals of marketing is taking place. The shift is so dramatic that it can, no doubt, be described as a paradigm shift[21]. Marketing researchers have been passionately convinced about the paradigmatic nature of marketing mix management and the Four P model[22]. To challenge marketing mix management as the basic foundation for all marketing thinking has been as heretic as it was for Copernicus to proclaim that the earth moved[23, 24].

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Since publication of the first edition of CRC Desk Reference of Clinical Pharmacology in 1998, dramatic discoveries in molecular medicine, along with rapid concomitant technological advances, have revolutionized the diagnosis and treatment of a broad range of human diseases with new medications. Given the rapid pace of new discovery, genetic- and cell-based therapeutics have now become a common part of the physicians’ armamentarium. A few examples will be given concerning two leading causes of death—cancer and cardiovascular diseases—to illustrate this....

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This second edition of Internet Resources for Nurses is expanded in scope and depth; it includes more content headings and additional features. Since the publication of the first edition in 2000, there has been a substantial increase in the information available to nurses through the Internet. We can expect that this trend will continue and that the number, depth, and scope of health care Web sites will increase dramatically as health care organizations more fully embrace the information resources available.

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Soft matter (or soft condensed matter) refers to a group of systems that includes polymers, colloids, amphiphiles, membranes, micelles, emulsions, dendrimers, liquid crystals, polyelectrolytes, and their mixtures. Soft matter systems usually have structural length scales in the region from a nanometer to several hundred nanometers and thus fall within the domain of “nanotechnology.” The soft matter length scales are often characterized by interactions that are of the order of thermal energies so that relatively small perturbations can cause dramatic structural changes in them.

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Asthma is now the most common chronic childhood disease, occurring in approximately 54 of every 1000 children (21). From 1980 through 1996, childhood asthma increased dramatically, by approximately 5% per year (14, 16, 26). The etiology of asthma is complex and multifactorial; risk factors include genetic predisposition as well as exposure to environmental and infectious triggers.

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Organizations continue to show dramatic differences in their ability to manage their health care cost trends. A group of organizations that we refer to as “consistent performers” has been successful in maintaining health care cost trends at or below the TW/NBGH norm for each of the last four years. Our research this year identii ed 43 companies that qualify as consistent performers. 4 Figure 8 shows that the ability to keep cost increases low over an extended period of time distinguishes these companies from other organizations.

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From its inception nearly 30 years ago, the optical subdiscipline now referred to as nonimaging optics, has experienced dramatic growth. The term nonimaging optics is concerned with applications where imaging formation is not important but where effective and efficient collection , concentration, transport and distribution of light energy is - i.e. solar energy conversion, signal detection, illumination optics, measurement and testing. This book will incorporate the substantial developments of the past decade in this field.

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