Drug eruptions

Part 2 book Dermatology - An illustrated colour text" includes content: Disorders of nails; vascular and lymphatic diseases; urticaria and angioedema, blistering disorders, connective tissue diseases, vasculitis and the reactive erythemas; Skin changes in internal conditions, drug eruptions, associations with malignancy, neurocutaneous disorders and other syndromes.

145p zizaybay1101 30-04-2024 3 2   Download

Methotrexate is an anticancer drug from the antimetabolite class. It is also used in gynecology and obstetrics and is the molecule of choice for the medical treatment of ectopic pregnancies. We report a case of toxidermia associated with severe pancytopenia induced by methotrexate for ectopic pregnancy.

5p vilazada 31-01-2024 3 2   Download

Part 2 book "Clinical dermatology" includes content: Infections, infestations, skin reactions to light, disorders of pigmentation, skin tumours, the skin in systemic disease, the skin and the psyche, other genetic disorders, drug eruptions, medical treatment, physical forms of treatment.

178p muasambanhan05 16-01-2024 1 0   Download

Adverse drug reactions are described as “A response to a medicine in a human which is noxious and unintended and which occur at any dosage and can also result from an overdose, misuse or abuse of a medicine. Adverse cutaneous drug reactions (ACDRs) are caused by a wide variety of drugs. Aim of the study is to determine the clinical patterns of drug eruptions and the common drugs implicated and determine the frequency of incriminating drugs for different patterns of CADRs.

10p nguaconbaynhay7 15-08-2020 19 1   Download

(bq) part 2 book "dermatology for advanced practice clinicians" presentation of content: superficial fungal infections, disorders of hair and nails, vasculitis and hypersensitivity, cutaneous drug eruptions, pigmentation and light related-dermatoses, genital dermatoses, wound care,... and other contents.

226p thangnamvoiva23 06-10-2016 49 6   Download

(BQ) Continued part 1, part 2 of the document Illustrated manual of pediatric dermatology - Diagnosis and management presents the following contents: Photodermatoses and physical injury and abuse, drug eruptions, pigmentary disorders, collagen vascular diseases, vascular and lymphatic diseases, hair disorders, nail disorders, genodermatoses and syndromes,...

223p thangnamvoiva5 14-07-2016 44 1   Download

(bq) nearly two decades after the first drug eruptions & reactions manual was compiled by dr. litt, this classic work has been developed and expanded into litt’s d.e.r.m. relied upon by dermatologists and medical practitioners internationally for its unparalleled practical focus on adverse effects and cutaneous reactions, this text is the essential quick-reference tool for patient care and drug safety.

77p thangnamvoiva5 14-07-2016 46 2   Download

(bq) part 2 book "litt's drug eruption reference manual including drug interactions" presents the following contents: drugs responsible for common reaction patterns, drugs responsible for common reaction patterns, alphabetical index of drug eruptions a–z

717p thangnamvoiva5 14-07-2016 24 2   Download

(bq) part 2 book "requisites in dermatology - pediatric dermatology" presents the following contents: drug eruptions and inflammatory eruptions of the skin; pigmentary disorders - white spots, brown spots and other dyschromias, lumps and bumps, skin conditions in newborns and infants, genetic disorders of the skin, disorders of hair and nails, the skin in systemic disease

113p thangnamvoiva5 14-07-2016 36 1   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Fixed drug eruption resulting from fluconazole use: a case report

4p thulanh30 19-12-2011 43 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Patch Testing in Non-Immediate Drug Eruptions...

9p thulanh10 09-10-2011 43 3   Download

Dịch tễ học Tần số: Trong các bệnh nhân dị ứng thuốc, hồng ban nhiễm sắc cố định chiếm khoảng 2-5% bệnh nhân điều trị nội trú, trên 1% bệnh nhân điều trị ngoại trú. Các nghiên cứu cho thấy, bệnh đứng hàng thứ hai hoặc thứ ba trong các phản ứng phụ của thuốc ở da. Chủng tộc: không có sự ưu thế về chủng tộc. Giới: tỷ lệ nam/nữ khoảng 1/1,1. Tuổi: bệnh nhân trẻ tuổi nhất là 1,5; bệnh nhân già nhất là 87. Nguyên nhân: kháng sinh, thuốc chống động kinh, NSAIDs,... Đường dùng: uống, đặt,...

4p thanhongan 14-12-2010 363 7   Download

Các hội chứng phát ban phồng nước hoặc bóng nước gây ra do thuốc, phản ứng phản vệ liên quan đến thuốc, tăng nhạy cảm với thuốc là những thể nặng trong các phản ứng phụ của thuốc. Các phát ban bóng nước do thuốc có thể phân loại thành các bệnh cảnh sau: -Dạng xốp hóa (spongiotic) hoặc dạng chàm (eczematous), -Ngoại ban mụn mủ toàn thân cấp tính (acute generalized exanthematous pustulosis), -Phát ban do thuốc cố định (fixed drug eruption), -Hồng ban đa dạng (erythema multiforme), hội chứng Stevens-Johnson, ly thượng bì hoại tử nhiễm độc (toxic epidermal...

5p thanhongan 14-12-2010 159 13   Download

Sulfonamides Antibacterial sulfonamides have a rather high risk of causing cutaneous eruptions and are among the drugs most frequently implicated in SJS and TEN. The combination of sulfamethoxazole and trimethoprim frequently induces adverse cutaneous reactions in patients with AIDS (Chap. 182). Desensitization is often successful in AIDS patients with morbilliform eruptions but is not recommended in AIDS patients who manifested erythroderma or a bullous reaction in response to their earlier sulfonamide exposure.

5p konheokonmummim 03-12-2010 70 3   Download

Allopurinol Together with sulfonamides and antiepileptics, allopurinol is one of the "usual suspects" that induce frequently mild maculopapular eruptions (in at least 3% of users) and may also cause more severe reactions including hypersensitivity/DRESS and SJS/TEN. Because of increasing utilization it is one of the most frequent causes of life-threatening reactions. Anti-HIV Medications In clinical trials, combinations of highly active antiretroviral treatments were frequently associated with ≥10% "drug eruptions.

5p konheokonmummim 03-12-2010 72 3   Download

These reactions are characterized by one or more sharply demarcated, erythematous lesions, sometimes leading to a blister. Hyperpigmentation results after resolution of the acute inflammation. With rechallenge, the lesion recurs in the same (i.e., fixed) location. Lesions often involve the lips, hands, legs, face, genitalia, and oral mucosa and cause a burning sensation. Most patients have multiple lesions. Fixed drug eruptions have been associated with phenolphthalein, sulfonamides, cyclines, dipyrone, NSAIDs, and barbiturates.

5p konheokonmummim 03-12-2010 66 3   Download

Delayed hypersensitivity mechanisms directed by drug-specific T cells are probably the most important mechanisms in the etiology of the most common drug eruptions—morbilliform exanthems—and also of rare and severe forms such as hypersensitivity syndrome, acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). Drugspecific T cells have been detected in these types of drug eruptions. Contrary to what has been believed for years, the antigen is more often the native drug itself than its metabolites.

5p konheokonmummim 03-12-2010 82 5   Download

Also systemic. f In adults, associated with renal failure and immunocompromised state. Vesicles and bullae are also seen in contact dermatitis, both allergic and irritant forms (Chap. 53). When there is a linear arrangement of vesicular lesions, an exogenous cause should be suspected. Bullous disease secondary to the ingestion of drugs can take one of several forms, including phototoxic eruptions, isolated bullae, Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) (Chap. 56).

4p konheokonmummim 30-11-2010 81 4   Download

Drug-induced erythroderma (exfoliative dermatitis) may begin as an exanthematous (morbilliform) eruption (Chap. 56) or may arise as diffuse erythema. A number of drugs can produce an erythroderma, including penicillins, sulfonamides, carbamazepine, phenytoin, gold, allopurinol, and zalcitabine. Fever and peripheral eosinophilia often accompany the eruption, and there may also be facial swelling, hepatitis, and allergic interstitial nephritis; this constellation is frequently referred to as drug reaction with eosinophilia and systemic symptoms (DRESS).

5p konheokonmummim 30-11-2010 60 5   Download