Encoding strategy

Ebook "Transgenesis and secondary metabolism" provides comprehensive reference information on the efficient production of secondary metabolites from plants by transgenesis and other genetic manipulation strategies. It reviews and summarizes selected important case studies in genetic methods applied to enhance the production of a given metabolite or a group of related or derived compounds.

652p tracanhphuonghoa1007 22-04-2024 7 3   Download

Mutations in the DMD gene encoding dystrophin—a critical structural element in muscle cells— cause Duchenne muscular dystrophy (DMD), which is the most common fatal genetic disease. Clustered regularly interspaced short palindromic repeat (CRISPR)-mediated gene editing is a promising strategy for permanently curing DMD.

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Precision medicine with gene panel testing based on next-generation sequencing for patients with cancer is being used increasingly in clinical practice. HER2, which encodes the human epidermal growth factor receptor 2 (HER2), is a potentially important driver gene. However, therapeutic strategies aimed at mutations in the HER2 extracellular domain have not been clarified.

11p vischultz 20-10-2023 2 1   Download

Knowledge of the pathogen-host interactions between the species is essentialin order to develop a solution strategy against infectious diseases. In vitro methods take extended periods of time to detect interactions and provide very few of the possible interaction pairs. Hence, modelling interactions between proteins has necessitated the development of computational methods. The main scope of this paper is integrating the known protein interactions between thehost and pathogen organisms to improve the prediction success rate of unknown pathogen-host interactions.

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Multicellular organisms adopt various strategies to tailor gene expression to cellular contexts including the employment of multiple promoters (and the associated transcription start sites (TSSs)) at a single locus that encodes distinct gene isoforms.

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Nanoscale metal-organic frameworks (MOFs) have appeared as potential materials in biomedical and sensing applications. In this work, a nano Zn-BDC-NH2 encoded MOF was effectively synthesized using the co-surfactants strategy and characterized for the curcumin adsorption.

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There is now a renewed interest in cancer vaccines. Patients responding to immune checkpoint blockade usually bear tumors that are heavily infiltrated by T cells and express a high load of neoantigens, indicating that the immune system is involved in the therapeutic effect of these agents; this finding strongly supports the use of cancer vaccine strategies.

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Aspergillus oryzae, a safe filamentous fungus, is widely used in food and enzyme production. In this study, we examined a cultivation model using rice husks as carrier to assess the capacity of recombinant protein production in A. oryzae. The model was first tested with the A. oryzae strain expressing the DsRed reporter gene. The expression of DsRed was easily detected by the pink color of the fungal mycelium on culture media and under a fluorescence microscope. The model was then evaluated with the phyA gene encoding a phytase from the fungus Aspergillus fumigatus.

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Encoding arbitrary digital information in DNA has attracted attention as a potential avenue for large scale and long term data storage. However, in order to enable DNA data storage technologies there needs to be improvements in data storage fidelity (tolerance to mutation), the facility of writing and reading the data (biases and systematic error arising from synthesis and sequencing), and overall scalability.

19p vihamax2711 21-04-2020 10 0   Download

As with many plant species, current genome editing strategies in soybean are initiated by stably transforming a gene that encodes an engineered nuclease into the genome. Expression of the transgene results in a double-stranded break and repair at the targeted locus, oftentimes resulting in mutation(s) at the intended site.

13p vihamax2711 21-04-2020 9 2   Download

In the domain of Systemic Functional Grammar (SFG), the term “nominalisation” is used to refer to non-congruent metaphorical modes of expression, which is a predominant tendency characteristic of grammatical metaphor (Halliday 1985/1994). As an alternative way of encoding verbal meanings, nominalisations perform important ideological functions.

5p vidanh95 12-12-2018 18 0   Download

The plastid transcription kinase (PTK), a component of the major RNA polymerase complex from mustard chloroplasts, has been implicated in redox-mediated regulation of plastid gene expression. A cloning strategy to define the PTK gene(s) resulted in the isolation of a full-length cDNA for a protein with overall high homology with the a subunit of cytosolic casein kinase (CK2) that contained an N-terminal extension for a putative plastid transit peptide.

9p system191 01-06-2013 44 3   Download

This paper presents a multilingual system designed to recognize named entities in a wide variety of languages (currently more than 12 languages are concerned). The system includes original strategies to deal with a wide variety of encoding character sets, analysis strategies and algorithms to process these languages.

4p bunthai_1 06-05-2013 48 2   Download

Likewise, understanding your audience will help you select the best channels for reaching specific audiences with your messages. People access information in different ways, at different times of the day, and for different reasons. Using market research, metrics, and other data to define your audience needs will be important in selecting the most effective channels. Each social media channel is different in the way it engages communities and manages content.

33p thamgiacongdong 02-05-2013 71 4   Download

Before we describe the investigation process, we need to define the basic and fundamental concepts. There are few agreed upon definitions in the area of digital forensic research, so we will clearly state the definitions we are using, even the most basic ones. Digital data are data represented in a numerical form. With modern computers, it is common for the data to be internally represented in a binary encoding, but this is not a requirement. A digital object is a discrete collection of digital data, such as a file, a hard disk sector, a network packet, a memory page, or a process....

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This report describes an efficient strategy for amplified functional purification of the human H1 receptor after heterologous expression in Sf9 cells. The cDNA encoding a C-terminally histidine-tagged (10xHis) human histamineH1 receptor was used to generate recombinant baculovirus in a Spodoptera frugiperda-derived cell line (IPLB-Sf9). As judged from its ligand affinity profile, functional receptor could be expressed at high levels (30–40 pmol per 10 6 cells).

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This book presents current topics in genetics in the dermatologic field. Various skin disorders are inherited as mendelian inheritance. Genetic skin disorders are caused by mutations in the genes encoding proteins expressing in skin, skin appendages, melanocytes and immune-associated cells. Identification of genes and elucidation of function of the encoded proteins may provide novel strategies to overcome the disorders.

168p phoebe75 19-02-2013 49 3   Download

Velocity encoded phase-contrast magnetic resonance imaging (VE-PC MRI) is another imaging technique used to noninvasively measure Achilles tendon strain and changes in its force-displacement relationship concomitant with chronic unloading and subsequent recuperation. This technique will be reviewed in terms of its ability to quantify the Achilles tendon Young’s modulus (MPa) from a stress-strain curve.

206p wqwqwqwqwq 21-07-2012 62 5   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Progressive and Error-Resilient Transmission Strategies for VLC Encoded Signals over Noisy Channels

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Enzyme replacement therapy (ERT) with α-galactosidase A (α-Gal A) is currently the most effective therapeutic strategy for patients with Fabry disease, a lysosomal storage disease. However, ERT has limitations of a short half-life, requirement for frequent administration, and limited efficacy for patients with renal failure. Therefore, we investigated the efficacy of recombinant adeno-associated virus (rAAV) vector-mediated gene therapy for a Fabry disease mouse model and compared it with that of ERT.

10p toshiba23 18-11-2011 54 3   Download