ESBL producing clinical isolates
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This study was done to assess the occurrence of virulence factors and correlation of phylogenetic grouping in ESBLs producing E. coli isolates from Palestine. Twenty-seven ESBLs producing E. coli isolates were collected between April and June 2013 from three hospitals in Gaza. Detection of genes encoding virulence factors, pathogenicity associated island marker (PAI) and phylogenetic groups were studied by PCR. The correlation of E. coli phylogenetic grouping with the virulence factors in the isolates was studied.
6p mudbound 10-12-2021 10 1 Download
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. This study was carried out on 120 urine specimen collected from catheterized patients, aged between 20-70 yrs. The screening for ESBL production was done by the disc diffusion test as recommended by the Clinical and Laboratory Standards Institute(CLSI) and confirmed by the phenotypic disc confirmatory test (PDCT) and ESBL Hi Crome agar(Hi media-Mumbai).
6p chauchaungayxua12 29-07-2021 4 1 Download
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Enterobacteriaceae are the most frequently isolated organisms from clinical specimens. Among them Escherichia coli and Klebsiella pneumoniae cause a wide variety of clinical infections. With the emergence of ESBLs, carbapenems became the drug of choice. During the past decade, there has been an emergence of carbapenems-resistant Enterobacteriaceae that produce carbapenamases.
6p caygaocaolon11 21-04-2021 11 1 Download
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The present study was done to detect the prevalence of ESBLs producing E. coli and Klebsiella spp with their antibiotic resistance patterns at TMMC Tertiary care hospital. A total no of 200 isolates were obtained from clinical samples from March to February 2015.
9p gaocaolon9 22-12-2020 17 1 Download
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Extended spectrum beta lactamase producers are posing a major obstacle in the therapeutic outcome of patients. They cause enzymatic hydrolysis of the beta lactum ring, resulting in resistance to penicillins and cephalosporins. The rise in ESBL producers results in prolonged treatment which leads to increased hospital stay and financial burden on the patient. It is necessary for all the hospitals to monitor ESBL producers to formulate preventive and therapeutic measures accordingly. The study was conducted in a tertiary care hospital during the period from December 2015 to November 2016.
7p angicungduoc8 07-11-2020 15 1 Download
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The aim of the study was to determine resistant pattern of urinary isolates and occurrence of extended spectrum beta- lactamase (ESBL) and Amp C production in them. Patients clinically suspected to be having urinary tract infection (UTI) were included in the study. This study was conducted in the Department of Microbiology, G. S Medical College & Hospital, Pilkhuwa, Uttar Pradesh over a period of 9 months from August 2016 to April 2017.
9p chauchaungayxua8 03-10-2020 13 1 Download
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The main aim of this study includes, to isolate and speciate the Klebsiella isolates from various clinical specimens from patients admitted in ICU. To determine the antibiotic susceptibility pattern of Klebsiella species by disc diffusion method. And to detect the presence of extended spectrum betalactamases (ESBL) by double disc synergy test and Inhibitor Potentiated disc diffusion test.
22p dayhoctainha 10-09-2020 25 1 Download
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Antimicrobial resistance is a growing threat worldwide. Increasing resistance to third generation cephalosporins has become a cause for concern. The prevalence of extended spectrum–lactamases (ESBLs) and metallobetalactamases (MBL) among members of Enterobacteriaceae constitutes a serious threat to current -lactam therapy leading to treatment failure. A total of 276 Gram negative isolates were processed. ESBL was detected by phenotypic confirmatory disc diffusion test (PCDDT) using ceftazidime alone and in combination with clavulanic acid.
8p angicungduoc6 20-07-2020 19 1 Download
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ESBL producing clinical isolates of gram negative organisms are major burden in hospital as well as in the community. These organisms are the causative agent for septicemia. Carbapenem group (Imipenem and Ertapenem) are the drug of choice for treating such infections. Recently increased incidences of resistance to Imipenem were reported, that makes the management of sepsis difficult.
7p quenchua6 15-06-2020 7 1 Download
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The present study was done to detect Extended spectrum β lactamase and metallo-βlactamase producing isolates of Pseudomonas aeruginosa from various clinical samples from patients admitted in Tirunelveli Government medical college hospital. In this study we studied the prevalence of ESBL and MBL among 112 Pseudomonas aeruginosa isolates, following standard methods of isolation and identification of these bacteria from clinical materials
8p kethamoi4 18-04-2020 15 0 Download
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The irrational and indiscriminate use of antibiotics has made antibiotic resistance as biggest health problem of India. Therefore, the present study was undertaken with the aim to isolate ESBL producing E. coli and Klebsiella from clinical human cases. A total of 100 urine samples of human were collected from pathology lab of Faizabad and Gorakhpur district and processed for isolation of E. coli and Klebsiella. All isolates were screened for ESBLs production by using Cefotaxim and Ceftazidime disk.
8p chauchaungayxua4 18-03-2020 13 0 Download
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The incidence of infections caused by multidrug resistant ESBL producing K.pneumoniae is on rise. The treatment of these infections have become increasingly difficult and life threatening. Knowledge on prevalence of these infections and corresponding antimicrobial susceptibility patterns is essential regionally. Routine standard operative procedures were followed in the laboratory in processing the clinical specimens for culture and sensitivity. ESBL producing K.pneumoniae were identified by phenotypic combination disc test. Majority of K.
6p cothumenhmong3 22-02-2020 24 2 Download
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The rapid emergence of multiresistant microbial pathogens is a serious threat to human health. Extended spectrum beta lactamase (ESBL)-producing Escherichia coli is a superbug causing worldwide outbreaks, CTX-M has become the most commonly detected ESBL genotype; these enzymes have become predominant worldwide, the most common type of CTX-M reported in various geographic regions is CTX-M15. A total of 80 Escherichia coli (E. coli) isolates were recovered from different clinical samples of intensive care units (ICUs) patients.
13p nguathienthan2 26-12-2019 17 1 Download
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K. pneumoniae is responsible for a wide variety of hospital and community-acquired infections, affecting patients with normal immune systems as well as those with pre-existing conditions. The Carbapenems are β-lactam antibiotics that are used in the treatment of infections caused by Extended Spectrum beta-Lactamases (ESBL) producing gram negative bacteria (GNB). Carbapenem antibiotics are considered the drugs of choice for the treatment of ESBL -producing Enterobacteriaceae and other multidrug resistant bacteria.
11p quenchua2 18-12-2019 10 0 Download
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Over the period of years infections caused by multidrug resistance organisms has emerged as a major public health problem. Their prevalence rates vary in different parts of the world and hence local data regarding these pathogens were important. Our study was aimed to identify the presence of ESBL and AmpC producing Enterobacteriaceae isolates from various clinical samples in our hospital setup various clinical samples were processed consecutively during the study period for microbiological analysis as per standard operating procedure.
9p quenchua2 16-12-2019 21 1 Download
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The aim of this study was to determine the prevalence of plasmid-mediated quinolone resistance qnr genes (A, B and S) among a collection of enterobacterial clinical pathogens resistant to ciprofloxacin and was ESBL producers from Sudan. Seventy-two isolates that were ciprofloxacin resistant and ESBL producer were screened by PCR for qnr genes (A, B and S). qnrA positive isolates were tested by PCR for class-1 integrons as well as resistance transfer by conjugation with sodium azide-resistant Escherichia coli J53. DNArelatedness was tested by PFGE.
7p kequaidan2 13-12-2019 24 0 Download
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Aggressive periodontitis (AgP) is one of the most severe forms of periodontal diseases. Extended Betalactamas producing (ESBL) bacteria don't respond to antibiotic treatment and cause failure of clinical practice. There is limited knowledge is available about incidence of ESBL bacteria in AgP. Therefore, the main aim of this study was to evaluate prevalence of ESBL bacteria in AgP. The present study was conducted for a period of one and half year from March 2017 to October 2018 at a tertiary care teaching hospital. Subgingival plaque samples were collected AgP patients.
6p kequaidan2 11-12-2019 16 1 Download
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Community-acquired bloodstream infections are the infections detected within 48 hours of hospitalization, showing positive blood culture and develop spontaneously without an association with any prior medical interventions. Aims of the study are to identify the clinical profile of patients, detect the pathogens causing community-acquired bloodstream infections (CA-BSI) and their antimicrobial susceptibility pattern and to perform the molecular characterization of resistant pathogens.
9p cothumenhmong1 10-12-2019 17 0 Download
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Extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae has tremendously increased worldwide and it is one of the most common causes of morbidity and mortality associated with hospital-acquired infections. This could be attributed to association of multi drug resistance in ESBL producing isolates. Therefore, in the present study, an attempt was made to know the rate of ESBL producing Enterobacteriaceae and to know their antibiogram at Dr. B.R. Ambedkar Medical College. Bangalore.
8p nguaconbaynhay1 04-12-2019 15 1 Download