ESBL producing Klebsiella pneumoniae
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Klebsiella pneumoniae is a leading cause of bloodstream infection (BSI). Strains producing extendedspectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies are urgently required, due to severely limited therapeutic options.
16p vibransone 28-03-2024 2 2 Download
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Enterobacteriaceae are the most frequently isolated organisms from clinical specimens. Among them Escherichia coli and Klebsiella pneumoniae cause a wide variety of clinical infections. With the emergence of ESBLs, carbapenems became the drug of choice. During the past decade, there has been an emergence of carbapenems-resistant Enterobacteriaceae that produce carbapenamases.
6p caygaocaolon11 21-04-2021 11 1 Download
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Antimicrobial resistance is a growing threat worldwide. Increasing resistance to third generation cephalosporins has become a cause for concern. The prevalence of extended spectrum–lactamases (ESBLs) and metallobetalactamases (MBL) among members of Enterobacteriaceae constitutes a serious threat to current -lactam therapy leading to treatment failure. A total of 276 Gram negative isolates were processed. ESBL was detected by phenotypic confirmatory disc diffusion test (PCDDT) using ceftazidime alone and in combination with clavulanic acid.
8p angicungduoc6 20-07-2020 19 1 Download
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Urinary tract Infections caused by extended-spectrum β-lactamase (ESBL), producing Klebsiella pneumoniae are on a rise all over the world with high morbidity and mortality. This study was carried out to determine the presence of TEM, SHV and CTX-M genes in extended-spectrum β-lactamase (ESBL) producing Klebsiella pneumoniae. A total of 300 Klebsiella pneumoniae isolates were collected and identified using traditional culturing and biochemical tests.
10p kethamoi6 29-06-2020 21 1 Download
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The use of plant products as medicine has emerged from traditional days to modern times of medicine in order to improve the quality life of the patients worldwide. Nature-derived medicines are considered safer with less or no side effects. The antibacterial effect of the leaves of Annona muricata was evaluated on bacterial strains of ESBLs: Escherichia coli and Klebsiella pneumoniae are tested which were isolated from D.Y. Patil Hospital, Nerul, NaviMumbai.
6p chauchaungayxua6 26-06-2020 14 1 Download
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The detection of extended- spectrum β-lactamase (ESBL) producing bacteria is important for infection control and epidemiological surveillance. The purpose of the present study was to compare two phenotypic methods for detection of ESBL positive Escherichia coli and Klebsiella pneumoniae in urinary isolates. This study was carried out in the Department of Microbiology, Rama Medical College, Kanpur(U.P), India from November 2015 to August 2016.
5p nguaconbaynhay6 23-06-2020 13 0 Download
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Extended spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-Kp) infection can cause significant morbidity and mortality in neonates. We investigated a nosocomial ESBL-Kp outbreak in a neonatal intensive care unit (NICU) of the University Hospital of Larissa (UHL), Central Greece.
8p vinatri2711 29-02-2020 13 1 Download
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The aim of this study was to determine the prevalence of aac(6')-Ib-cr gene among seventy-two urinary and wound enterobacterial pathogens that were ciprofloxacin-resistant and ESBL producers from the Sudan. All the seventy-two isolates were screened by PCR for the presence of the aac(6')- Ib-cr gene. The new variant of the aminoglycoside acetyle transferase enzyme (aac(6')-Ib-cr) gene was detected among 52 of the 72 test isolates (72%) including Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae and Salmonella spp.
6p cothumenhmong3 22-02-2020 12 0 Download
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The incidence of infections caused by multidrug resistant ESBL producing K.pneumoniae is on rise. The treatment of these infections have become increasingly difficult and life threatening. Knowledge on prevalence of these infections and corresponding antimicrobial susceptibility patterns is essential regionally. Routine standard operative procedures were followed in the laboratory in processing the clinical specimens for culture and sensitivity. ESBL producing K.pneumoniae were identified by phenotypic combination disc test. Majority of K.
6p cothumenhmong3 22-02-2020 24 2 Download
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The drug resistance among the gram negative bacteria is present as a serious global problem. ESBLs and MBLs are the important members of beta-lactamases produced mainly by gram negative bacteria and are responsible for mediating resistance to extendedspectrum cephalosporins and carbapenem. These enzymes are commonly detected in the members of the Enterobacteriaceae like Klebsiella pneumoniae and Escherichia coli. A cross-sectional study was conducted at Department of Microbiology, Santosh Medical College & Hospital Ghaziabad by using K. pneumoniae isolated from sputum samples.
7p chauchaungayxua3 07-02-2020 17 0 Download
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K. pneumoniae is responsible for a wide variety of hospital and community-acquired infections, affecting patients with normal immune systems as well as those with pre-existing conditions. The Carbapenems are β-lactam antibiotics that are used in the treatment of infections caused by Extended Spectrum beta-Lactamases (ESBL) producing gram negative bacteria (GNB). Carbapenem antibiotics are considered the drugs of choice for the treatment of ESBL -producing Enterobacteriaceae and other multidrug resistant bacteria.
11p quenchua2 18-12-2019 10 0 Download
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Over the period of years infections caused by multidrug resistance organisms has emerged as a major public health problem. Their prevalence rates vary in different parts of the world and hence local data regarding these pathogens were important. Our study was aimed to identify the presence of ESBL and AmpC producing Enterobacteriaceae isolates from various clinical samples in our hospital setup various clinical samples were processed consecutively during the study period for microbiological analysis as per standard operating procedure.
9p quenchua2 16-12-2019 21 1 Download
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The aim of this study was to determine the prevalence of plasmid-mediated quinolone resistance qnr genes (A, B and S) among a collection of enterobacterial clinical pathogens resistant to ciprofloxacin and was ESBL producers from Sudan. Seventy-two isolates that were ciprofloxacin resistant and ESBL producer were screened by PCR for qnr genes (A, B and S). qnrA positive isolates were tested by PCR for class-1 integrons as well as resistance transfer by conjugation with sodium azide-resistant Escherichia coli J53. DNArelatedness was tested by PFGE.
7p kequaidan2 13-12-2019 24 0 Download