Extremely heterogeneous

The heart is one of the least regenerative organs in the human body; adult cardiac myocytes divide at extremely low frequency. Therefore, meaningful induction of cardiac regeneration requires in-depth understanding of myocyte cell-cycle control. Recent insights into how myocytes can be coaxed into duplicating in vivo might inform emerging therapeutics.

3p vibransone 28-03-2024 2 2   Download

Adrenal ganglioneuroblastoma is an extremely rare tumor among adrenal neoplasms in adult. We reported a 26-year-old young female patient presented with vague pain in left plank. Abdominal sonography and CTScan revealed a heterogenous solid lobulated left adrenal mass which contenting central necrosis, hemorrhage, coarse calcification and multiple adjacent metastasized lymphoid nodules, hence adrenal cortical carcinoma was not excluded although testing for adrenal function were normal.

6p vigeorge 06-12-2023 4 1   Download

In the present study, trichomes of 70 spp. from nine genera and pollens of 53 spp. from six genera were investigated using scanning electron microscopy (SEM) in order to draw the taxonomic conclusion of tribe Stachydeae. Trichome characters that can provide adequate variation in delimitation of taxa were: presence or absence of glandular or nonglandular trichomes, number of cells (uni-/bi-/multicellular), presence of extremely long trichomes (i.e.

27p lyhuyenthu 31-01-2023 4 2   Download

Cancer is an extremely complex disease. Recent largescale studies have revealed fascinating insights into the genetic make-up of multiple tumor entities, but numerous challenges remain.

4p vialfrednobel 29-01-2022 15 0   Download

The results of Monte Carlo simulation were generally in accordance with the detected contamination and risk levels, except for several elements (Cu and Zn) with huge spatial heterogeneity. According to the Monte Carlo simulation, the river sediments could undergo extremely high contamination and high ecological risk of the PTEs in the worst situation

9p thebadguys 15-01-2022 11 0   Download

Integrating genome-wide gene expression patient profiles with regulatory knowledge is a challenging task because of the inherent heterogeneity, noise and incompleteness of biological data. From the computational side, several solvers for logic programs are able to perform extremely well in decision problems for combinatorial search domains.

14p vicolorado2711 23-10-2020 23 1   Download

Cancer is an extremely heterogeneous group of diseases traditionally categorized according to tissue of origin. However, even among patients with the same cancer subtype the cellular alterations at the molecular level are often very different.

10p vijisoo2711 30-09-2020 9 1   Download

Patient response to chemotherapy for ovarian cancer is extremely heterogeneous and there are currently no tools to aid the prediction of sensitivity or resistance to chemotherapy and allow treatment stratification. Such a tool could greatly improve patient survival by identifying the most appropriate treatment on a patient-specific basis.

32p vialabama2711 21-09-2020 35 1   Download

Ovarian cancer (OC) is extremely heterogeneous and most cases are advanced stages at diagnosis. OC has a high response rate initially, but becomes resistant to standard chemotherapy. We previously employed high throughput global shRNA sensitization screens to identify NF-kB related pathways.

13p vimale2711 25-08-2020 9 2   Download

The use of nomograms for prognostication of individual cancer patients has been recommended in order to facilitate precision medicine. However, models for patients with soft tissue sarcomas (STSs) are limited because of the rarity and heterogeneity of such cancers.

12p vikuala271 13-06-2020 13 1   Download

The initial survey showed a high level of spatial heterogeneity in the location of industries in Jepara. For subsequent sampling and more detailed analysis of a subset of these enterprises, the area was divided into squares, each of which would be independently surveyed. The theoretical optimal size of the squares was calculated using the standard interpolation method, with weighted distances. Details are given in Annex 1 and the resulting grid is illustrated in Figure 2. The spatial heterogeneity is so extreme that 80% of the workshops are located in only 17% of the squares.

60p can_thai 10-12-2012 53 7   Download

The rickettsiae are a heterogeneous group of small, obligately intracellular, gram-negative coccobacilli and short bacilli, most of which are transmitted by a tick, mite, flea, or louse vector. Except for louse-borne typhus, humans are incidental hosts. Among rickettsiae, Coxiella burnetii, Rickettsia prowazekii, and R. typhi have the well-documented ability to survive for an extended period outside the reservoir or vector and to be extremely infectious: inhalation of a single Coxiella microorganism can cause pneumonia. High infectivity and severe illness after inhalation make R.

26p crazy_sms 08-05-2012 51 5   Download

Introduction Nowadays, the communication possibilities between automation systems are a core demand and necessity, even in the case of systems of the lower performance class. Due to the large variety of communication processors, protocols and user interfaces in the SIMATIC homogenous system world (i.e. only SIMATIC systems communicate with each other) and particularly in the heterogeneous system world (i.e. SIMATIC systems communicate with “third party” automation systems) this topic is extremely complex.

185p chuottuan 30-09-2010 103 26   Download