![](images/graphics/blank.gif)
Functionally related genes
-
Ovarian cancer (OC) is a gynecological malignancy tumor with high recurrence and mortality rates. Programmed cell death (PCD) is an essential regulator in cancer metabolism, whose functions are still unknown in OC. Therefore, it is vital to determine the prognostic value and therapy response of PCD-related genes in OC.
17p
vishanshan
27-06-2024
1
1
Download
-
This research aimed to create a robust signature with hypoxia-related genes to predict the prognosis of breast cancer patients. The function of hypoxia genes was further studied through cell line experiments.
12p
vishanshan
27-06-2024
3
1
Download
-
This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.
15p
vikoch
27-06-2024
1
1
Download
-
The primary aim of Cerebral Signal Transduction: From First to Fourth Messengers, therefore, is to offer a comprehensive picture of the recent advances made in the signaling field as it relates to neuronal and cere bral function. The current state of progress provides an exciting opportunity for such a comprehensive focus because molecular tools have become available to selectively remove, reduce, or enhance spe cific components in the signaling pathways, e. g. , by interfering with the genes encoding key proteins.
441p
vimeyers
29-05-2024
3
2
Download
-
Ebook "Systems biology of RNA binding proteins" provides case studies of RNA binding proteins that regulate aspects of RNA processing that are important for fundamental understanding of diseases and development. Chapters include systems-level perspectives, mechanistic insights into RNA processing and RNA Binding proteins in genetic variation, development and disease. The content focuses on systems biology and genomics of RNA Binding proteins and their relation to human diseases.
474p
ladongphongthanh1008
22-04-2024
6
1
Download
-
Ebook "Prokaryotic systems biology (Advances in experimental medicine and biology, Volume 883)" focuses on innovative experimental and computational approaches for charting interaction networks in bacterial species.
326p
duongthandue0501
28-02-2024
3
1
Download
-
Ebook "Geomicrobiology: Molecular and environmental perspective" covers the interaction of microorganisms with geological activities resulting in processes influencing development of the Earth's geo- and biospheres. Addresses environmental proteomics, functional gene arrays, isotope labelling, bioinformatics & related techniques to analyze relationships & functions of microbes in complex, natural communities.
445p
tachieuhoa
28-01-2024
3
2
Download
-
Bladder urothelial carcinoma (BLCA) is the most common genitourinary cancer and the prognosis of patients is often poor. However, studies of basement membrane-related genes (BM-related genes) in BLCA are less reported. Therefore, we established a BM-related genes signature to explore their functional and prognostic value in BLCA.
15p
vileonardodavinci
23-12-2023
6
2
Download
-
Cantharidin (CTD) is the active ingredient of Chinese medicine, which has been traditionally used in multiple cancers treatment, especially in hepatocellular carcinoma (HCC). However, a comprehensive analysis of the CTD-related molecular mechanism is still necessary to understand its functions in HCC treatment. This study aimed to reveal the novel molecular targets and regulatory networks of CTD in HCC.
14p
vileonardodavinci
23-12-2023
6
2
Download
-
Pancreatic cancer (PC) is a highly malignant tumor featured with high intra-tumoral heterogeneity and poor prognosis. Cell-in-cell (CIC) structures have been reported in multiple cancers, and their presence is associated with disease progression. Nonetheless, the prognostic values and biological functions of CIC-related genes in PC remain poorly understood.
24p
vialfrednobel
23-12-2023
7
5
Download
-
Part 2 book "Nutritional and physiological functions of amino acids in pigs" includes content: Amino acids and hormone secretion in pigs, amino acids, gene expression, and cell signaling in the pig intestine, amino acids and immune functions, the pig model for studying amino acid related human diseases - amino acids and intestinal diseases in preterm infan... and other contents.
153p
oursky07
24-10-2023
8
2
Download
-
TAP1 is an immunomodulation-related protein that plays different roles in various malignancies. This study investigated the transcriptional expression profile of TAP1 in uveal melanoma (UVM), revealed its potential bio-logical interaction network, and determined its prognostic value.
14p
vischultz
20-10-2023
2
1
Download
-
Oral squamous cell carcinoma (OSCC) is a common malignant tumor associated with poor prognosis. MicroRNAs (miRNAs) play crucial regulatory roles in the cancer development. However, the role of miRNAs in OSCC development and progression is not well understood. Methods We sought to establish a dynamic Chinese hamster OSCC animal model, construct miRNA differential expression profiles of its occurrence and development, predict its targets, and perform functional analysis and validation in vitro.
19p
vischultz
20-10-2023
6
2
Download
-
This research aimed to investigate the roles of fanconi anemia complementation group D2 (FANCD2) on the regulation of ferroptosis in osteosarcoma progression. The function of FANCD2 on cell viability, invasion, migration, and tumor growth were explored. FANCD2 and pathway-related genes were determined by western blot. Ferroptosis-associated markers were determined, including lipid peroxidation, labile iron pool (LIP), ferrous iron (Fe2+), and ferroptosis-related genes.
11p
vischultz
20-10-2023
4
1
Download
-
Insulin-like growth factor binding proteins (IGFBPs) are critical regulators of the biological activities of insulin-like growth factors. The IGFBP family plays diverse roles in different types of cancer, which we still lack comprehensive and pleiotropic understanding so far.
31p
vischultz
20-10-2023
4
1
Download
-
The epithelial-mesenchymal transition (EMT) plays an indispensable role in the development and progression of Endometrial cancer (EC). Nevertheless, little evidence is reported to uncover the functionality and application of EMT-related molecules in the prognosis of EC. This study aims to develop novel molecular markers for prognosis prediction in patients with EC.
16p
vioracle
29-09-2023
5
3
Download
-
Many mammals are well adapted to surviving in extremely cold environments. These species have likely accumulated genetic changes that help them efficiently cope with low temperatures. It is not known whether the same genes related to cold adaptation in one species would be under selection in another species.
11p
vinarcissa
21-03-2023
1
1
Download
-
In the study, the identification of trehalose-6- phosphate synthase (TPS) genes stress-related in cotton, and the genetic structure analysis and molecular evolution analysis of TPSs were conducted with bioinformatics methods, which could lay a foundation for further research of TPS functions in cotton.
11p
vinarcissa
21-03-2023
1
1
Download
-
Diabetes and obesity are multifactorial diseases caused by a complex interaction of environmental and genetic factors, with the latter consisting of multiple susceptibility genes, making it difficult to clarify their functions and interactions in conferring susceptibility to diabetes and obesity in humans.
10p
vinarcissa
21-03-2023
2
1
Download
-
In mammals, an important source of genomic variation is insertion polymorphism of retrotransposons. These may acquire a functional role when inserted inside genes or in their proximity. The aim of this work was to carry out a genome wide analysis of ERE1 retrotransposons in the horse and to analyze insertion polymorphism in relation to evolution and function.
16p
vinarcissa
21-03-2023
4
1
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)