Gene duplication

The aim of this study was to investigate the duplication events within the SABATH gene family in cassava using computational tools. By analyzing the similarities between coding DNA sequences, we identified potential duplicated gene pairs and examined their structures. In addition, we assessed the expression profiles of SABATH genes across various cassava tissues during key growth and developmental stages.

10p viaburame 14-03-2025 6 1   Download

The cellular retinoic acid-binding protein type I (CRABPI) is encoded by a single gene in mammals. We have characterized twocrabp1genes in zebra-fish, designatedcrabp1a and crabp1b. These twocrabp1 genes share the same gene structure as the mammalianCRABP1genes and encode proteins that show the highest amino acid sequence identity to mammalian CRAB-PIs. The zebrafishcrabp1aandcrabp1bwere assigned to linkage groups 25 and 7, respectively.

11p fptmusic 11-04-2013 32 2   Download

Thebandccrystallins are evolutionarily related families of proteins that make up a large part of the refractive structure of the vertebrate eye lens. Each family has a distinctive gene structure that reflects a history of succes-sive gene duplications. A survey ofc-crystallins expressed in mammal, rep-tile, bird and fish species (particularly in the zebrafish, Danio rerio) has led to the discovery of cN-crystallin, an evolutionary bridge between theband cfamilies.

16p awards 06-04-2013 42 3   Download

Molecular phylogeny among catalase–peroxidases, cyto-chromecperoxidases, and ascorbate peroxidases was ana-lysed. Sixty representative sequences covering all known subgroups of class I of the superfamily of bacterial, fungal, and plant heme peroxidases were selected. Each sequence analysed contained the typical peroxidase motifs evolved to bind effectively the prosthetic heme group, enabling per-oxidatic activity.

13p awards 05-04-2013 60 6   Download

We previously reported that zebrafishaB-crystallin is not constitutively expressed in nervous or muscular tissue and has reduced chaperone-like activity compared with its human ortholog. Here we characterize the tissue expression pattern and chaperone-like activity of a second zebrafish aB-crystallin.

10p dell39 27-03-2013 37 4   Download

The main mechanisms shaping the modular evolution of proteins are gene duplication, fusion and fission, recombination and loss of frag-ments. While a large body of research has focused on duplications and fusions, we concentrated, in this study, on how domains are lost.

11p inspiron33 26-03-2013 40 5   Download

Polyamine oxidases (PAOs, EC 1.5.3.11) are key enzymes responsible for the terminal catabolism of polyamines in plants, bacteria and protozoa. In barley, two PAO isoforms (HvPAO1 and HvPAO2) have been previously analyzed as regards their tissue expression and subcellular localization.

13p inspiron33 25-03-2013 49 5   Download

Fatty acid-binding protein type 1 (FABP1), commonly termed liver-type fatty acid-binding protein (L-FABP), is encoded by a single gene in mam-mals. We cloned and sequenced cDNAs for two distinct FABP1s in zebra-fish coded by genes designatedfabp1a andfabp1b. The zebrafish proteins, FABP1a and FABP1b, show highest sequence identity and similarity to the human protein FABP1.

14p inspiron33 25-03-2013 40 3   Download

Temperature acclimation in poikilotherms entails metabolic rearrangements provided by variations in enzyme properties. However, in most cases the underlying molecular mechanisms that result in structural changes in the enzymes are obscure.

11p galaxyss3 21-03-2013 20 3   Download

We describe the structure of a fatty acid-binding protein 11 (fabp11b) gene and its tissue-specific expression in zebrafish. The 3.4 kb zebrafishfabp11b is the paralog of the previously described zebrafish fabp11a, with a deduced amino acid sequence for Fabp11B exhibiting 65% identity with that of Fabp11A.

10p galaxyss3 07-03-2013 44 4   Download

Genomic and cDNA sequences coding for a fatty acid-binding protein (FABP) in zebrafish were retrieved from DNA sequence databases. The cDNA codes for a protein of 14.7 kDa (pI= 5.94), and the gene consists of four exons, properties characteristic of most vertebrate FABP genes. Phylogenetic analyses using vertebrate FABPs indicated that this protein is most similar to zebrafish Fabp10.

11p viettel02 20-02-2013 37 3   Download

The structure of the thyroid hormone distributor protein, transthyretin, has been highly conserved during the evolution of vertebrates. Over the last decade, studies into the evolution of transthyretin have revealed the exis-tence of a transthyretin homolog, transthyretin-like protein, in all king-doms. Phylogenetic studies have suggested that the transthyretin gene in fact arose as a result of a duplication of the transthyretin-like protein gene in early protochordate evolution.

13p viettel02 20-02-2013 35 2   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Structure, expression differentiation and evolution of duplicated fiber developmental genes in Gossypium barbadense and G. hirsutum

15p panasonic02 14-12-2011 58 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Phylogenetic detection of numerous gene duplications shared by animals, fungi and plants...

0p thulanh22 20-11-2011 59 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Tandem repeats modify the structure of human genes hosted in segmental duplications...

0p thulanh21 15-11-2011 68 5   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Divergence of exonic splicing elements after gene duplication and the impact on gene structures...

0p thulanh21 15-11-2011 50 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Simultaneous transcription of duplicated var2csa gene copies in individual Plasmodium falciparum parasites...

0p thulanh21 15-11-2011 42 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Genome-wide comparative analysis of the Brassica rapa gene space reveals genome shrinkage and differential loss of duplicated genes after whole genome triplication...

0p thulanh21 15-11-2011 44 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans...

0p thulanh21 12-11-2011 38 2   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Coding region structural heterogeneity and turnover of transcription start sites contribute to divergence in expression between duplicate genes...

0p thulanh21 12-11-2011 41 3   Download