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Genetic divergence
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Changes in medical practice are needed to improve the diagnosis of monogenic forms of selected common diseases. This article seeks to focus attention on the need for universal genetic testing in common diseases for which the recommended clinical management of patients with specific monogenic forms of disease diverges from standard management and has evidence for improved outcomes.
10p
viellison
28-03-2024
4
2
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Part 1 book "Genetics and evolution of infectious diseases" includes content: Recent developments in the definition and official names of virus species; a theory based pragmatism for discovering and classifying newly divergent species of bacterial pathogens, population structure of pathogenic bacteria, epidemiology and evolution of fungal pathogens in plants and animals, clonal evolution, coevolution of host and pathogen, microbes as tracers of past human demography and migrations, phylogenetic analysis of pathogens,... and other contents.
332p
oursky07
23-10-2023
5
1
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The study was carried out with twenty-four genotypes of rice during the Spring season, 2020 in Hanoi, Vietnam in order to exploit the attributes and divergence of quality properties from existing rice cultivars in North Vietnam. The rice genotypes were characterized based on ten quality parameters of milling, physical appearance and physiochemical characters using Mahalanobis D2 statistic
10p
viengels
25-08-2023
2
2
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White striping (WS) is an emerging quality defect with adverse consequences for the sensorial, technological, and nutritional qualities of breast meat in broiler chickens.
9p
vinarcissa
21-03-2023
2
1
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Pomacea canaliculata is an important invasive species worldwide. However, little is known about the molecular mechanisms behind species displacement, adaptational abilities, and pesticide resistance, partly because of the lack of genomic information that is available for this species.
13p
vinarcissa
21-03-2023
2
1
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Previous studies suggest that the metabolic pathway structure influences the selection and evolution rates of involved genes. However, most of these studies have exclusively considered a single gene copy encoding each enzyme in the metabolic pathway.
12p
vinarcissa
21-03-2023
6
1
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High isoelectric point α-amylase genes (Amy1) play major roles during cereal seed germination, and are associated with unacceptable high residual α-amylase activities in ripe wheat grains.
17p
vihagrid
30-01-2023
7
3
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Drip loss is a key aspect of meat quality. Transcriptome profiles of muscle with divergent drip loss would offer important insight into the genetic factors responsible for the trait. Our study revealed some GO terms, pathways and potential candidate genes affecting drip loss. It provides crucial information to understand the molecular mechanism of drip loss, and would be of help for improving meat quality of pigs.
9p
vihagrid
30-01-2023
7
3
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Wheat leaf rust is an important disease worldwide. Understanding the pathogenic molecular mechanism of Puccinia triticina Eriks. (Pt) and the inconstant toxic region is critical for managing the disease. The present study aimed to analyze the pathogenic divergence between Pt isolates.
11p
vihagrid
30-01-2023
7
3
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Feather pecking (FP) is damaging behavior in laying hens leading to global economic losses in the layer industry and massive impairments of animal welfare. The objective of the study was to discover genetic variants and affected genes that lead to FP behavior.
14p
vihagrid
30-01-2023
10
3
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Marine fish populations are often characterized by high levels of gene flow and correspondingly low genetic divergence. This presents a challenge to define management units. Goldsinny wrasse (Ctenolabrus rupestris) is a heavily exploited species due to its importance as a cleaner-fish in commercial salmonid aquaculture. However, at the present, the population genetic structure of this species is still largely unresolved.
15p
vihagrid
30-01-2023
10
3
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Selection for feed efficiency is one of the best ways to decrease poultry production costs and environ‑ mental impacts. While literature on its genetic determinism is abundant, it is limited to one or a few periodic values over the animals’ lifespans.
11p
vihagrid
30-01-2023
8
3
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While the evolutionary divergence of cis-regulatory sequences impacts translation initiation sites (TISs), the implication of tandem repeats (TRs) in TIS selection remains largely elusive. Here, we employed the TIS homology concept to study a possible link between TRs of all core lengths and repeats with TISs.
11p
vihagrid
30-01-2023
8
3
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Plant domestication provides a unique model to study genome evolution. Many studies have been conducted to examine genes, genetic diversity, genome structure, and epigenome changes associated with domestication.
16p
vigalileogalilei
27-02-2022
14
1
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The evolution of sex chromosomes has occurred many times in highly divergent taxa. The bulk of the research that has shaped our expectations for their evolutionary path has focused on model organisms that have older sex chromosomes; In these organisms, the two sex chromosomes are highly differentiated from each other in form and function.
3p
vialfrednobel
29-01-2022
7
0
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Cotton has been cultivated and used to make fabrics for at least 7000 years. Two allotetraploid species of great commercial importance, Gossypium hirsutum and Gossypium barbadense, were domesticated after polyploidization and are cultivated worldwide. Although the overall genetic diversity between these two cultivated species has been studied with limited accessions, their population structure and genetic variations remain largely unknown.
13p
vialfrednobel
29-01-2022
12
0
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Tetracentron sinense is an endemic and endangered deciduous tree. It belongs to the Trochodendrales, one of four early diverging lineages of eudicots known for having vesselless secondary wood.
30p
viarchimedes
26-01-2022
9
0
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Mouse models have allowed for the direct interrogation of genetic effects on molecular, physiological, and behavioral brain phenotypes. However, it is unknown to what extent neurological or psychiatric traits may be human- or primate-specific and therefore which components can be faithfully recapitulated in mouse models.
33p
viarchimedes
26-01-2022
7
0
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In population genomics, genetic diversity measures play an important role in genome scans for divergent sites. In population epigenomics, comparable tools are rare although the epigenome can vary at several levels of organization.
29p
viarchimedes
26-01-2022
12
0
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Phylogenetic trees are useful tools to infer evolutionary relationships between genetic entities. Phylogenetics enables not only evolution-based gene clustering but also the assignment of gene duplication and deletion events to the nodes when coupled with statistical approaches such as bootstrapping. However, extensive gene duplication and deletion events bring along a challenge in interpreting phylogenetic trees and require manual inference.
7p
langthannam
29-12-2021
14
0
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