Genetic polymorphisms

The objective of this study was to investigate the association of the RNF4, RBP4, and IGF2 genotypes, and their additive genetic effects on litter size of Landrace and Yorkshire pig breeds.

7p vibecca 01-10-2024 1 1   Download

This study aimed to estimate the allelic and genotypic frequencies of single nucleotide polymorphisms (SNPs) of MC4R (melanocortin-4- receptor gene) and PIT1 (pituitary specific transcription factor-1) genes, and their additive dominance genetic effects on production and carcass traits in Duroc pigs.

7p vibecca 01-10-2024 1 1   Download

The aims of this study are to determine the properties and efficiency of the SCoT and CBDP techniques in estimating the genetic diversity and variation of two S. lessoniana populations in Con Dao and Phu Quoc.

16p viling 27-09-2024 4 2   Download

Cathelicidins include antimicrobial peptides (AMPs) and are involved in the innate immune defense against infections in mammals. Polymorphisms in the DNA sequence of cathelicidin genes could be relevant to inherited variations of host innate immunity, adaptation, and pathogen resistance. This study aims to investigate the sequence polymorphism of cathelicidin genes including CATHL2 and CATHL4 from local indigenous yellow cattle breeds of Vietnam.

11p dianmotminh02 03-05-2024 11 2   Download

Wilms tumor is a highly heritable malignancy. Aberrant METTL14, a critical component of N6-meth‑ yladenosine (m6 A) methyltransferase, is involved in carcinogenesis. The association between genetic variants in the METTL14 gene and Wilms tumor susceptibility remains to be fully elucidated.

10p vielonmusk 21-01-2022 20 0   Download

Risk prediction models incorporating single nucleotide polymorphisms (SNPs) could lead to individualized prevention of colorectal cancer (CRC). However, the added value of incorporating SNPs into models with only traditional risk factors is still not clear. Hence, our primary aim was to summarize literature on risk prediction models including genetic variants for CRC, while our secondary aim was to evaluate the improvement of discriminatory accuracy when adding SNPs to a prediction model with only traditional risk factors.

21p vielonmusk 21-01-2022 14 1   Download

The aim of the thesis research: Determine the polymorphisms of MC4R, PIT1, GH, LEP, PIK3C3 genes and their association with the traits of growth performance, backfat thickness, and reproductive performance in Duroc pigs; determine the polymorphism of ADRB3, ACSL4, FABP3, PLIN2 genes and the association with the intramuscular fatin Duroc pigs; select the Duroc pig line in the direction of growth performance using the support from genotype information.

28p guitaracoustic08 04-01-2022 16 2   Download

Research objective: Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p extraenglish 24-05-2021 25 4   Download

Establish the genetic variants database of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Identification of genotype and allele frequencies of 04 genes CYP2C9, CYP2C19, CYP2D6 and CYP3A5 in Kinh Vietnamese. Perform in silico functional analysis of novel variants.

27p capheviahe27 23-02-2021 5 3   Download

Genetic diversity among 28 sesame (Sesamum indicum L.) varieties was examined at DNA level by means of random amplified polymorphic DNA (RAPD) analysis. Fifteen primers used produced a total of 132 RAPD fragments. Each primer generated 3 to 26 amplified fragments with an average of 8.8 bands per primer. Based on pair-wise comparisons of RAPD amplification products, Nei and Li’s similarity coefficients were computed to assess the associations among the varieties. Pair-wise similarity indices varied from 0.35 to 0.84.

8p cothumenhmong7 09-09-2020 19 2   Download

Assessment of genotype diversity was studied using released and in pipeline genotypes of wheat, of these 22 were released and 14 were in pipeline . Genetic diversity among 36 wheat genotypes was studied using Random amplified polymorphic DNA (RAPD) analysis. 21 RAPD primers (RPI primers) were used for screening 36 wheat genotypes from which 2,868 fragments were amplified. It was observed that 63.3% bands were polymorphic and 36.4% were monomorphic. The percent of polymorphic bands in banding pattern was calculated and it was highest in RPI-22 (81.3%) while lowest was recorded in RPI-2 (33.

8p chauchaungayxua6 26-06-2020 14 3   Download

Single-nucleotide polymorphisms (SNP) are common genetic changes in the human genome. In recent time, many scientists have shown their interests in studies on SNPs’ roles in the pathological risk especially in cancer and metabolic diseases.

27p tamynhan0 15-06-2020 18 1   Download

In this study, a total of sixteen RAPD primers were used for evaluation of the genetic diversity of eight H. serrata samples collected from different locations of Sa Pa and Da Lat. Overall, sixteen markers generated a total of 70 fragments in 8 collected samples of H. serrata. Of seventy generated fragments, 44 were found to be polymorphic.

6p shiwo_ding7 05-06-2019 22 1   Download

Mục tiêu của nghiên cứu "Sự đa dạng di truyền của 15 Locus str trên nhiễm sắc thể thường trong quần thể người Khmer sống ở tỉnh Sóc Trăng, Việt Nam" nhằm xây dựng được bảng tần suất alen và các chỉ số thông kê cho 15 locus STR trên NST thường của 110 cá thể người Khmer khỏe mạnh, không có quan hệ huyết thống và sống tại tỉnh Sóc Trăng, Việt Nam.

9p estupendo5 31-08-2016 70 3   Download

Humanb2 -glycoprotein I (b2 GPI), also known as apolipo-protein H, has been implicated in haemostasis and the pro-duction ofanti-phospholipid antibodies. There is a wide range ofinterindividual variation in b2GPI plasma levels that is thought to be under genetic control, but itsmolecular basis remains unknown. To understand the genetic basis of b2GPI variation, we analyzed the 5¢ flanking region ofthe b2GPIgene for mutation detection by DHPLC and identi-fied a point mutation at the transcriptional initiation site ()1CfiA) with a carrier frequency of 12.1%. ...

9p tumor12 20-04-2013 36 3   Download

Human 8-oxoguanine-DNA glycosylase (OGG1) efficiently removes muta-genic 8-oxo-7,8-dihydroguanine (8-oxoGua) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine when paired with cytosine in oxidatively damaged DNA. Excision of 8-oxoGua mispaired with adenine may lead to GfiT transversions.

14p vinaphone15 25-02-2013 41 3   Download

Khái niệm: Khái niệ Dấu (Marker) = đặc điểm dùng để̉ phân biệt/nhận diện điể dùng đê biệ t/nhậ diệ Dấu di truyền (Genetic Marker) = đặc điểm dùng để̉ phân điể dùng đê biệt/nhận diện về̀ bản chất di truyền biệ t/nhậ diệ vê bản chấ truyề Dấu phân tử (DNA Marker) = đặc điểm ADN dùng để phân biệt/nhận diện (về bản chất di truyền) Ứng dụng: Dùng để phân biệt/nhận diện sự khác nhau (về bản chất di truyền) giữa các cá thể/giống/loài Yêu cầu: + Khác nhau (Polymorphism) giữa các cá thể/các giống/các loài + mang...

20p trada85 22-01-2013 176 16   Download

Inheritance is the practice of passing on property, titles, debts, rights and obligations upon the death of an individual. It represents also to pass a characteristic, genetically. It has long played an important role in human societies. The rules of inheritance differ between societies and have changed over time.

31p trada85 20-01-2013 40 4   Download

This study characterized the human apolipoprotein H [APOH; b2-glycopro-tein I (b2GPI)] promoter and its variants byin vitro functional experiments and investigated their relationship with human plasmab2GPI levels. We examined the individual effects of 12 APOHpromoter single nucleotide polymorphisms in the 5¢ flanking region ofAPOH(1.4 kb) on luciferase activity in COS-1 cells and HepG2 cells and their impact on plasma...

13p mobifone23 18-01-2013 48 3   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis)

11p panasonic06 25-12-2011 52 4   Download