HSP70 protein
-
Ebook "Networking of chaperones by co-chaperones" describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets.
152p ladongphongthanh1008 22-04-2024 4 4 Download
-
In ebook "Heat shock protein inhibitors: Success stories" the science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry.
243p lamquandat 28-12-2023 5 2 Download
-
Mục tiêu của nghiên cứu này nhằm đánh giá đa hình gen heat shock protein 70 (HSP70) trên vùng trình tự mã hóa của nhóm vịt lai (Trống Star53 x Mái Biển) bằng kỹ thuật PCR-RFLP. ADN ly trích từ 60 mẫu máu cá thể vịt lai (30 mẫu trống và 30 mẫu mái) được sử dụng để thực hiện phản ứng PCR khuếch đại đoạn gen HSP70 với kích thước 572bp.
5p viintuit 06-09-2023 5 1 Download
-
Part 1 of ebook "Heat shock proteins in veterinary medicine and sciences" presents the following content: domestic animals; thermotolerance in domestic ruminants - a HSP70 perspective; heat shock protein expression and implications in spontaneous animal tumors - veterinary and comparative aspects; poultry animals; heat shock protein and thermal stress in chicken;...
196p dieptieuung 14-07-2023 4 1 Download
-
Xác định và phân tích các gen mã hóa HSP70 ở cây sắn (Manihot esculanta) bằng phương pháp tin sinh học trình bày xác định và phân tích đặc điểm của các gene Hsp70 bằng các phương pháp tin sinh học ở cây sắn, loại cây lương thực lấy củ nhiệt đới quan trọng. Kết quả nghiên cứu là tiền đề cho các nghiên cứu về chọn tạo giống loại cây lương thực có giá trị này cũng như tiền đề cho các nghiên cứu sâu hơn về chức năng của họ Hsp70.
10p vimalfoy 08-02-2023 6 2 Download
-
Head and neck squamous cell carcinoma (HNSCC) is one severe malignancy driven by complex cellular and signalling mechanisms. However, the roles of circular RNAs (circRNAs) in HNSCC’s development remains poorly understood.
16p viangelamerkel 27-07-2022 5 1 Download
-
Heat shock protein (Hsp) gene family members in the watermelon genome were identified and characterized by bioinformatics analysis. In addition, expression profiles of genes under combined drought and heat stress conditions were experimentally analyzed. In the watermelon genome, 39 genes belonging to the sHsp family, 101 genes belonging to the Hsp40 family, 23 genes belonging to the Hsp60 family, 12 genes belonging to the Hsp70 family, 6 genes belonging to the Hsp90 family, and 102 genes belonging to the Hsp100 family were found.
16p thiencuuchu 27-11-2021 7 1 Download
-
Heat shock proteins (HSPs) are found extensively in Eukaryotes and are involved in stress tolerance. However, their functions in herbaceous peony (Paeonia lactiflora Pall.) under high temperature stress are poorly characterized.
11p vigiselle2711 30-08-2021 6 1 Download
-
Heat shock proteins have important functions in regulating plant growth and response to abiotic stress. HSP70 family genes have been described in several plant species, but a comprehensive analysis of the HSP70 family genes in cabbage has not been reported to date, especially their roles in floral development.
14p visilicon2711 20-08-2021 11 1 Download
-
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease of unknown etiology. Genetic variation within different major histocompatibility complex (MHC) loci contributes to the susceptibility to IPF. The effect of 70 kDa heat shock proteins (HSP70) gene polymorphisms in the susceptibility to IPF is unknown.
8p vimontana2711 05-04-2021 14 2 Download
-
Hundreds of HSP40s derived from various species have been identified, of which several proteins are involved in spermatogenesis. DNAJB13 is a type II HSP40/DnaJ protein. In a previous study, we cloned mouse Dnajb13, which is up-regulated in cryptorchidism.
7p vimariana2711 22-12-2020 7 0 Download
-
Nghiên cứu này được thực hiện nhằm đánh giá tính đa hình di truyền gen stress nhiệt Hsp70 ở bốn giống gà: Ri, TP, HA và LV. Hai vị trí đa hình vùng bắt đầu mã hoá gen Hsp70, tại vị trí 258 có đột biến từ nucleotide A (Adenin) chuyển thành G (Guanin) và tại vị trí 276 có sự đột biến từ nucleotide C (Cytosin) chuyển thành G (Guanin), được tiến hành phân tích bằng phương pháp giải trình tự.
10p vigeorgia2711 03-12-2020 32 0 Download
-
The Bag (Bcl-2 associated athanogene) family of proteins consists of 6 members sharing a common, single-copied Bag domain through which they interact with the molecular chaperone Hsp70. Bag5 represents an exception in the Bag family since it consists of 5 Bag domains covering the whole protein.
11p vijisoo2711 29-09-2020 8 1 Download
-
Celastrol is a promising anti-tumor agent, yet it also elevates heat shock proteins (HSPs), especially HSP70, this effect believed to reduce its anti-tumor effects. Concurrent use of siRNA to increase celastrol’s antitumor effects through HSP70 interference has been reported, but because siRNA technology is difficult to clinically apply, an alternative way to curb unwanted HSP70 elevation caused by celastrol treatment is worth exploring.
9p virose2711 25-09-2020 15 1 Download
-
Heat shock protein (Hsp) 90 and Hsp70 are indispensable for cell survival under conditions of stress. They bind to client proteins to assist in protein stabilization, translocation of polypeptides across the cell membrane, and recovery of proteins from aggregates in the cell.
12p vilisa271 22-09-2020 31 1 Download
-
Colorectal cancer (CRC) is the third leading cause of cancer related deaths worldwide both in men and women. Our recent studies have indicated an association of heat shock protein 70–2 (HSP70-2) with bladder urothelial carcinoma.
13p vimale2711 25-08-2020 7 1 Download
-
Heat Shock Protein 70 (HSP70) is one of the important molecular chaperon that can protect cells from thermal damage by involving in the maintenance of the intra cellular homeostasis primarily by controlling the process of protein folding. The indigenous breeds of cattle have been found to be more resistant to heat stress in comparison to the exotic breeds by way of expressing HSP70 as an adaptive response.
9p nguaconbaynhay7 15-08-2020 12 1 Download
-
The oncoprotein MYC has the dual capacity to drive cell cycle progression or induce apoptosis, depending on the cellular context. BAG1 was previously identified as a transcriptional target of MYC that functions as a critical determinant of this cell fate decision.
14p viputrajaya2711 22-06-2020 6 1 Download
-
Heat shock proteins (HSPs) usually act as molecular chaperones to prevent proteins from being denatured in response to high temperature and other extreme conditions. These are highly conserved from prokaryotes to eukaryotes. In this study, we analysed the differential expression pattern of hsp21 and hsp70 transcript during thermal stress in tropical tasar silkworm. We found expression of hsp21 and hsp70 were upregulated ~2.5 and 4 folds respectively in the temperature treated larvae in comparison to the control larvae.
7p quenchua6 15-06-2020 14 1 Download
-
Bag-1 (Bcl-2-associated athanogene) is a multifunctional anti-apoptotic protein frequently overexpressed in cancer. Bag-1 interacts with a variety of cellular targets including Hsp70/Hsc70 chaperones, Bcl-2, nuclear hormone receptors, Akt and Raf kinases.
13p vikuala271 13-06-2020 8 1 Download