Human immunodeficiency virus pathogenesis

Part 2 book "Principles of virology (4/E - Vol 2: Pathogenesis and control)" includes content: Human immunodeficiency virus pathogenesis, vaccines, antiviral drugs, evolution, emergence, unusual infectious agents.

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Infection with human papillomavirus (HPV) is necessary for the development of cervical carcinoma. By contrast, the role of HPV in the pathogenesis of other malignancies, such as head and neck cancers, is less well characterised.

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Each year, 8.8 million patients are newly diagnosed with active TB and 1.6 million patients die of TB. The rapid spread of the human immunodeficiency virus has fueled the TB epidemic, especially in sub-Saharan Africa, where 28% of TB patients are HIV positive (WHO 2007). The current first-line treatment for TB is a multidrug regimen consisting of rifampin, isoniazid, pyrazinamide, and ethambutol (RIZE). Several major problems are associated with the currently available TB treatment.

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