Human larynx cancer

Emerging evidences proposed that microRNAs are associated with regulation of distinct physiopathological processes including development of normal stem cells and carcinogenesis. In this study we aimed to investigate microRNA profile of cancer stem-like cells (CSLCs) isolated form freshly resected larynx cancer (LCa) tissue samples.

11p vimale2711 25-08-2020 7 1   Download

To evaluate the antitumor effects of the combination treatment with measles vaccine virus and nimotuzumab in vivo. Materials and methods: We used human larynx cancer cell to form tumors on nude mice by xenograft model and to evaluate the anti-cancer effects of measles vaccine virus + nimotuzumab combination by assessing the survival time of mice and the rate of tumor cells induced apoptosis.

8p visamurai2711 25-07-2019 10 0   Download

The aim of this study is: To assess the anti-cancer effects of 131I-nimotuzumab on immune deficient mouse bearing human laryngeal cancer. In this study, we used EGFR-specific monoclonal antibody, nimotuzumab in combination with 131I to form 131I-nimotuzumab complex, and evaluated the antitumor activity of this complex in immunocompromised mice xenografted with the human laryngeal cancer line Hep2. This is the initial basis for the development of this complex application for laryngeal cancer treatment in the future.

8p trieusuper 14-09-2018 20 2   Download