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Human lung cells
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CCR8-expressing regulatory T cells (Tregs) are selectively localized within tumors and have gained attention as potent suppressors of anti-tumor immunity. This study focused on CCR8+ Tregs and their interaction with CD8+ T cells in the tumor microenvironment of human lung cancer.
12p
vishanshan
27-06-2024
1
1
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Ebook "Dendritic cell protocols" provides chapter and verse for many useful practical approaches to the art of studying dendritic cells. The book gives information on the usual techniques for derivation of human dendritic cells from precursor stem cells, such as monocytes. In addition it provides data on the difficult tasks of isolating dendritic cells directly from different tissues; whether dendritic cells from precursor cells or from tissues of mouse or human are required, this book contributes practical information.
489p
dongmelo
27-05-2024
10
2
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Single-cell transcriptome profiling has enabled highresolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.
3p
vibransone
28-03-2024
8
2
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Recent studies show that human gut microbial composition can determine whether a patient is a responder or non-responder to immunotherapy but have not identified a common microbial signal shared by responding patients.
15p
viellison
28-03-2024
8
2
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ung cancer, one of the most common malignant tumors, exhibits high inter- and intra-tumor heterogeneity which contributes significantly to treatment resistance and failure. Single-cell RNA sequencing (scRNA-seq) has been widely used to dissect the cellular composition and characterize the molecular properties of cancer cells and their tumor microenvironment in lung cancer.
18p
viellison
28-03-2024
4
2
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Ebook "Stem cells in the respiratory system" focuses on reviewing the most relevant—and recent—ideas on using local, endogenous, and exogenous progenitor/stem cells in preventing and treating injury to the lung. The lungs are one of the most complex organs in the human body, with a mature adult lung boasting at least 40 morphologically differentiated cell lineages.
175p
tachieuhoa
28-01-2024
6
2
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Relationship between cancer cell glycolysis and the landscape of tumor immune microenvironment in human cancers was investigated. Forty-one fresh lung adenocarcinoma (ADC) tissues were analyzed using flow cytometry for comprehensive immunoprotein. Formalin-fixed tissues were immunostained for hexokinase-2 (HK2) to assess cancer cell glycolysis.
11p
vileonardodavinci
23-12-2023
6
3
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SET domain containing 6 (SETD6) has been shown to be upregulated in multiple human cancers and can promote malignant cell survival. However, expression and function of SETD6 in lung adenocarcinoma (LUAD) remains unaddressed. This study aimed to demonstrate the expression pattern, biological roles and potential mechanisms by which SETD6 dysregulation is associated with LUAD.
12p
vileonardodavinci
23-12-2023
4
2
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Accumulating evidence has revealed that the gut microbiota influences the effectiveness of immune checkpoint inhibitors (ICIs) in cancer patients. As a part of the human microbiome, Helicobacter pylori (H. pylori) was reported to be associated with reduced effectiveness of anti-PD1 immunotherapy in patients with non-small-cell lung cancer (NSCLC).
8p
vialfrednobel
23-12-2023
7
3
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Anlotinib is a multi-targeted receptor tyrosine kinase inhibitor (TKI) which has exhibited encouraging clinical activity in advanced non-small cell lung cancer (NSCLC) and soft tissue sarcoma. The present study aims to investigate the combinatory antitumor efect of anlotinib and raltitrexed on human esophageal squamous carcinoma cells and further explore the molecular mechanisms in vitro.
15p
vischultz
20-10-2023
3
1
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Wilms’ tumour gene 1 (WT1) is clearly recognized as a tumour promoter in diversiform of human malignancies. Nevertheless, knowledge of its expression, functions and potential molecular mechanisms in non-small cell lung cancer (NSCLC) remains elusive.
15p
vioracle
29-09-2023
4
2
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Ebook "Metabolism of human diseases: Organ physiology and pathophysiology" examines the physiology of key organs (e.g. brain, eye, lung, heart, blood vessels, blood, immune system, gastrointestinal tract, pancreas, liver, fat tissue, kidney, reproductive system, teeth, bone and joints) and how defective metabolism and signaling pathways within these organs contribute to common human diseases. The book also describes commonly used drugs and explains their molecular targets.
382p
tukhongthienlac
24-06-2023
11
3
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To investigate pegylated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) safety and efficacy in preventing haematological toxicity during concurrent chemoradiotherapy (CCRT) for small-cell lung cancer (SCLC).
10p
vikolindagrabar
27-07-2022
6
2
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BCD-021 is a bevacizumab biosimilar which was shown to be equivalent to reference bevacizumab in a wide panel of physicochemical studies as well as preclinical studies in vitro and in vivo.
13p
vipriyankagandhi
27-07-2022
1
1
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Recombinant human granulocyte colony-stimulating factor (rhG-CSF) reduces neutropenia events and is widely used in cancer patients receiving chemotherapy. However, the effects of rhG-CSF on distant organ metastasis (DOM) in non-small-cell lung cancer (NSCLC) patients following postoperative chemotherapy are not clear.
13p
viangelamerkel
27-07-2022
3
1
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The WNT signal pathway has myriad family members, which are broadly involved in embryonic development and human cancer. Over-activation of WNT-β-Catenin signalling promotes cancer cell proliferation and survival.
14p
viangelamerkel
27-07-2022
4
1
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Ectopic Cushing’s syndrome (ECS) associated with malignant tumors, such as small cell lung carcinoma, bronchial carcinoids, and pheochromocytoma, has been reported in human medicine. However, ECS related to pheochromocytoma has not been reported in dogs.
7p
vigalileogalilei
28-02-2022
14
1
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Tumors comprise a complex microenvironment of interacting malignant and stromal cell types. Much of our understanding of the tumor microenvironment comes from in vitro studies isolating the interactions between malignant cells and a single stromal cell type, often along a single pathway.
22p
viarchimedes
26-01-2022
8
0
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The results demonstrate that the PM10 mass collected were higher than those reported by the local governmental agencies and the PMs are mainly constituted by hematite and quartz. EDS analysis showed the presence of Fe, Si, Mg, Al, Zi, Ca, and emerging metallic contaminants, such as Ba and Ti, in environmental samples.
15p
thebadguys
15-01-2022
19
0
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The objective of this study was to evaluate the toxicity assessment of Pseudomonas silesiensis strain A3 CuNPs against human normal (Wi38) and cancer (A549) cell lines as well as antimicrobial activity agent.
8p
schindler
30-12-2021
8
0
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