In vivo application

Ebook "Modified nucleic acids" spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs.

280p ladongphongthanh1008 22-04-2024 3 1   Download

Ebook "Molecular beacons" explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications.

201p coduathanh1122 27-03-2024 2 1   Download

Ebook "Crossroads between Innate and Adaptive immunity II" is designed to serve as a forum to discuss the most recent progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of development in complement basic research and the advent and application of new experimental approaches in this field have now allowed us to take an integrated view of the in vivo biology of the complement system.

138p cotieubac1004 15-03-2024 4 0   Download

Ebook "Regenerating the heart: Stem cells and the cardiovascular system" organizes the field into a digestible body of knowledge. Its four sections cover mechanical regeneration, electrical regeneration, cardiac tissues and in vivo stem cell therapies.

555p tachieuhoa 28-01-2024 4 2   Download

Ebook "Biotechnology of neglected and underutilized crops" has 16 chapters divided into 4 sections. Section 1 has three chapters dealing with Chenopodium as a potential food source, thin cell layer technology in micropropagation of Jatropha, and Panax vietnamensis. Section 2 deals with molecular biology and physiology of Haberlea rhodopensis, cell trait prediction in vitro and in vivo of legumes, and application of TILLING in orphan crops.

455p lucchinguyen 28-12-2023 6 2   Download

Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are of potential magnetic resonance imaging (MRI) contrast agents for tumor diagnosis. However, ultrasmall particle size or negative surface charge lead to relative short half-life which limit the utilization of USPIO for in vivo MRI contrast agents.

10p vileonardodavinci 23-12-2023 4 2   Download

To create chimeric antigen receptor (CAR) T cells and evaluate the effect on CD19+ B cells in animal models of acute lymphoblastic leukemia. Methods: An experimental research (In vitro and In vivo) was conducted at the Department of Pathophysiology, Military Medical University, from June 2019 to 2022.

11p vipierre 29-09-2023 9 2   Download

Polyploidization is an important technique used in grape breeding to create new genetic resources and can be induced using some antimitotic agents, including colchicine. Plants with increased ploidy can gain better quality than their original diploids in some characteristics. "Induction of polyploidy in grapevine (Vitis vinifera L.) seedlings by in vivo colchicine applications" was carried out to obtain polyploid genotypes under in vivo conditions.

8p lyhuyenthu 31-01-2023 3 2   Download

Hydroxyapatite-associated bacterial cellulose (BC/HA) is a promising composite for biomedical applications. However, this hybrid composite has some limitations due to its low in vivo degradability. The objective of this work was to oxidize BC and BC/HA composites for different time periods to produce 2,3 dialdehyde cellulose (DAC).

10p viginny 30-12-2022 8 2   Download

Alumosilicate materials zeolites are widely exploited due to porous structure and ion-exchange properties in several industrial, agriculture and veterinary applications. The mainly used zeolite for medical purposes in animals and humans is the natural zeolite clinoptilolite.

11p vironald 15-12-2022 7 3   Download

CRISPR/dCas9 is a versatile tool that can be used to recruit various effectors and fluorescent molecules to defined genome regions where it can modulate genetic and epigenetic markers, or track the chromatin dynamics in live cells. In vivo applications of CRISPR/dCas9 in animals have been challenged by delivery issues. We generate and characterize a mouse strain with dCas9-EGFP ubiquitously expressed in various tissues.

7p vigalileogalilei 27-02-2022 19 2   Download

In equine abdominal surgery, resection and anastomosis of strangulated intestine is a commonly performed procedure. To date, ligatures, vessel sealing devices and the ligate-divide stapler have been described for this use in horses. The objective of this study was to compare the application of haemostatic clips and ligatures to occlude equine mesenteric vessels.

5p vigandhi 23-02-2022 35 1   Download

Positional weight matrix (PWM) is a de facto standard model to describe transcription factor (TF) DNA binding specificities. PWMs inferred from in vivo or in vitro data are stored in many databases and used in a plethora of biological applications. This calls for comprehensive benchmarking of public PWM models with large experimental reference sets.

18p viarchimedes 26-01-2022 9 0   Download

The PRP is currently used in various medical fields, including orthopedic, plastic surgery, dermatology, dentistry, musculoskeletal and obstetrics-gynecology. To date, the results from in vitro, in vivo studies to clinical trials have proved the effectiveness of PRP in the treating of many diseases. Altogether, PRP is considered to be a very promising futuristic therapy by dint of its simple and highly potential clinical application.

11p meyerowitz 25-12-2021 10 0   Download

Reporter methods to quantitatively measure the efficiency and specificity of genome editing tools are important for the development of novel editing techniques and successful applications of available ones. However, the existing methods have major limitations in sensitivity, accuracy, and/or readiness for in vivo applications.

10p visilicon2711 20-08-2021 9 1   Download

Diseased, injured, or dysfunctional skeletal muscles may demonstrate abnormal function and contractility. Currently, only few in vivo imaging techniques are able to characterize the contractile properties of muscle tissue. This study aimed to test the hypothesis that muscle strain can be tracked in two upper extremity skeletal muscles by speckle-tracking ultrasonography (STU) and correlates with isometric muscle contractions.

8p vivermont2711 28-01-2021 7 2   Download

The present study was conducted during 2013- 2014 to find out the effect of induced mutation on in vivo growth parameters in „Camarosa‟ strawberry by following CRD factorial design. For the induction of variation explants (Runner tips, shoot tips and leaf disc) were subjected to different concentrations (0.1%, 0.2%, 0.3% and 0.4%) of EMS along with control for various treatment durations (1.5 hr, 2.5 hr and 3.5 hr).

12p angicungduoc8 07-11-2020 14 2   Download

In previous studies, we found that doxorubicin-conjugated antiCD137 mAb selectively killed CD137-expressing T cells in vitro. Therefore, in this work we tried to test the ability of this conjugate in vivo. C57lb/6 mice were induced with acute GVHD for further examination.

6p tamynhan8 04-11-2020 7 2   Download

The rate of microscopic incomplete resections of gastrointestinal cancers including pancreatic cancer has not changed considerably over the past years. Future intra-operative applications of tissue tolerable plasmas (TTP) could help to address this problem.

10p viirene2711 03-10-2020 16 1   Download

Application of dendritic cells (DC) for cancer immunotherapy involves tumor-associated immunogenic antigens for effective therapeutic strategies. The present study investigated whether DC co-cultured with autologous cytokine-induced killer cells (CIK) could induce a more specific immune response against liver cancer stem cells (LCSC) generated from human hepatocellular carcinoma (HCC) cells in vitro and in vivo.

10p vimanila2711 25-06-2020 14 1   Download