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Inducible vector
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Vaccine-induced thrombotic thrombocytopenia is associated with the coronavirus disease 2019 vaccines. It has been reported by vector-based vaccines. To the best of our knowledge, there is no report about vaccineinduced thrombotic thrombocytopenia in whole-virus vaccines. We are presenting the first case of vaccine-induced thrombotic thrombocytopenia with this type of vaccine.
5p
vitiki
30-01-2024
4
2
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Part 2 book "Arthropods as vectors of emerging diseases" includes content: Flies as vectors of microorganisms potentially inducing severe diseases in humans and animals; flies as vectors of parasites potentially inducing severe diseases in humans and animals; lice as vectors of bacterial diseases; triatomines as vectors of american trypanosomiasis; fleas as underestimated vectors of agents of diseases; marine crustaceans as potential hosts and vectors for metazoan parasites; spotted fever rickettsiae and rickettsioses in germany.
189p
oursky10
07-12-2023
5
3
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Part 1 book "Viral vectors in veterinary vaccine development - A textbook" includes content: Introduction to veterinary vaccines, what is required to develop a viral vector vaccine: key components of vaccine induced immune responses, viruses and the evolution of viral vectors, the role of adjuvants in the application of viral vector vaccines, adenovirus vectors, poxvirus vectors, the construction and evaluation of herpesvirus vectors.
117p
oursky05
20-09-2023
7
1
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In the regulation of gene expression, particularly abiotic-stress tolerance characteristics in plants, inducible promoters play an essential role in ensuring the endurance and productivity of crops. In several previous studies, the ZmDREB2.7 gene and some DNA polymorphisms in its promoter have been shown to enhance drought tolerance traits in maize (Zea mays L.).
10p
vicaptainmarvel
21-04-2023
2
2
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Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector population control methods, such as the sterile insect technique, are receiving renewed interest.
10p
vihagrid
30-01-2023
5
3
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The CRISPR/Cas9 system has recently been engineered to confer resistance to geminiviruses in plants. However, we show here that the usefulness of this antiviral strategy is undermined by off-target effects identified by deep sequencing in Arabidopsis. We construct two virus-inducible CRISPR/Cas9 vectors that efficiently inhibit beet severe curly top virus (BSCTV) accumulation in both transient assays (Nicotiana benthamiana) and transgenic lines (Arabidopsis).
7p
vigalileogalilei
27-02-2022
28
1
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Vesicular stomatitis (VS) is an acute, highly contagious and economically important zoonotic disease caused by the vesicular stomatitis virus (VSV). There is a need for effective and safe stable recombinant vaccine for the control of the disease. The human type 5 replication-defective adenovirus expression vector is a good way to construct recombinant vaccines.
9p
vidarwin
23-02-2022
7
1
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n the present work, a pioneering attempt has been made to overexpress master regulator binary transcription factor complex formed by HlWRKY1 and HlWDR1 using a plant expression vector to enhance the level of prenylflavonoid and bitter acid content in the hop. Subsequently, we performed transcriptional profiling using high-throughput RNA-Seq technology in leaves of resultant transformants and wild-type hop to gain in-depth information about the genome-wide functional changes induced by HlWRKY1 and HlWDR1 overexpression.
18p
vitzuyu2711
29-09-2021
6
1
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Flavescence dorée is the most serious grapevine yellows disease in Europe. It is caused by phytoplasmas which are transmitted from grapevine to grapevine by the leafhopper Scaphoideus titanus. Differences in susceptibility among grapevine varieties suggest the existence of specific genetic features associated with resistance to the phytoplasma and/or possibly with its vector.
27p
visilicon2711
20-08-2021
6
1
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The AIG (avrRpt2-induced gene) family of GTPases, characterized by the presence of a distinctive AIG1 domain, is mysterious in having a peculiar phylogenetic distribution, a predilection for undergoing expansion and loss, and an uncertain functional role, especially in invertebrates.
20p
vijeeni2711
24-07-2021
10
0
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Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations giving rise to the infective form, the metacyclic promastigotes.
16p
vijeeni2711
30-06-2021
7
1
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Transmission of pathogens by vector mosquitoes is intrinsically linked with mosquito’s reproductive strategy because anautogenous mosquitoes require vertebrate blood to develop a batch of eggs. Each cycle of egg maturation is tightly linked with the intake of a fresh blood meal for most species.
14p
vilichoo2711
23-06-2021
22
1
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The ecdysone inducible system was generated for checking the toxicity of target gene which was transected into the cells. The transcription unit, modified ecdysone receptor (IND) was cloned into vector pcDNA-Dest40 to form the new inducible expression plasmid pDest40-IND via cloning technique. A clear band with size about 487bp of PCR product indicated the success of amplification IND promoter.
8p
trinhthamhodang1218
18-03-2021
10
1
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In conclusion, the inducer-free expression vectors carrying Pspac promoters allow the constitutive expression of heterologous recombinant proteins at low levels in B. subtilis.
7p
nguaconbaynhay10
20-02-2021
7
1
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In this study, we constructed inducer-free expression plasmids carrying Pspac, a well-known IPTG-inducible promoter, by removing a part of the lacI gene.
7p
nat_qb73
21-02-2021
12
1
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Nuclear receptors (NRs) form a large family of ligand-inducible transcription factors that regulate gene expressions involved in numerous physiological phenomena, such as embryogenesis, homeostasis, cell growth and death.
13p
vioklahoma2711
19-11-2020
6
1
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Word representations support a variety of Natural Language Processing (NLP) tasks. The quality of these representations is typically assessed by comparing the distances in the induced vector spaces against human similarity judgements.
13p
viconnecticut2711
28-10-2020
6
0
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Directly targeting therapeutic suicide gene to a solid tumor is a hopeful approach for cancer gene therapy. Treatment of a solid tumor by an effective vector for a suicide gene remains a challenge. Given the lack of effective treatments, we constructed a bifidobacterial recombinant thymidine kinase (BF-rTK) -ganciclovir (GCV) targeting system (BKV) to meet this requirement and to explore antitumor mechanisms.
15p
vimale2711
25-08-2020
10
1
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Inorganic or inorganic-organic hybrid nanomaterials have great potential for applications in the biomedical fields. Biological half-life is an essential pharmacokinetic parameter for these materials to function in vivo. Compared to inductively coupled plasma mass spectrometry (ICP-MS), which is the gold standard, laser-induced breakdown spectroscopy (LIBS) is a faster and more efficient elemental detection method. We investigated an efficient way to quantify the metabolic rate using LIBS.
9p
covid19
14-06-2020
15
2
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The nucleotide sequence of this gene showed 97% identity to its homolog in GenBank (ID: JK287445.1) used as the control strain in our research. To generate host-induced gene silencing constructs which can potentially silence the expression of Minc16281 gene, two artificial microRNAs were synthesized based on the miR319a structure of Arabidopsis thaliana and inserted into an expression vector in soybean.
8p
tomhiddleston
25-05-2020
11
0
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