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Lethal dose
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Nghiên cứu được thực hiện nhằm đánh giá độc tính cấp và bán trường diễn theo đường uống của dung dịch EATWELLB trên động vật thực nghiệm. Nghiên cứu độc tính cấp được tiến hành trên chuột nhắt trắng chủng Swiss theo đường uống và xác định liều gây chết 50% chuột (lethal dose, LD50) theo phương pháp Litchfied-Wilcoxon.
11p
vikoch
27-06-2024
1
1
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To determine the hypnotic and analgesic effects of brimonidine, and evaluate its efficacy and safety for general anesthesia. Potentiation of pentobarbital sleeping time following brimonidine administration was observed in mice, as was the analgesic activity of brimonidine.
12p
vidietmarhopp
28-12-2021
7
0
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Fluralaner is a novel isoxazoline insecticide with a unique action site on the γ-aminobutyric acid receptor (GABAR), shows excellent activity on agricultural pests including the common cutworm Spodoptera litura, and significantly influences the development and fecundity of S. litura at either lethal or sublethal doses.
11p
vijeeni2711
24-07-2021
9
0
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The fungicide fludioxonil over-stimulates the fungal response to osmotic stress, leading to overaccumulation of glycerol and hyphal swelling and bursting. Fludioxonil-resistant fungal strains that are null-mutants for osmotic stress response genes are easily generated through continual sub-culturing on sub-lethal fungicide doses.
15p
vilichoo2711
25-06-2021
9
1
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In this study, hard wood cuttings of Hibiscus rosa-sinenis Cultivar Red Single were treated with nine different dose of gamma rays (1 to 5 k R) and ten different concentrations of EMS ranging from 0.1% to 1.0%. The results revealed that gradual reduction in survival of cuttings, shoot length, leaf length and leaf width with increase in dosage of gamma rays and EMS. However gamma rays treated plants showed significant gradual reduction in growth rate than the EMS treated plants. Based on probit analysis, LD50 (Lethal dose) value for gamma radiation and EMS have been fixed as 2.81 kR and 0.
8p
chauchaungayxua10
19-03-2021
16
2
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The present investigation was undertaken to study the effect of non particulate gamma radiation and EMS mutagens on linseed varieties viz., Baner, Him Alsi-2 and Surbhi. Many significant effects of EMS concentration and gamma rays dosages on seed germination were observed.
8p
chauchaungayxua10
18-03-2021
30
2
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The present study investigated the effect of gamma irradiation and NaCl treatment on the embryonic calli of indica rice variety Kuliyadichan and CO43. Embryonic calli obtained from both the varieties were exposed to gamma irradiation (0, 20, 30, 40 and 50 Gy) and lethal dose LD50 based on calli survival and regeneration capacity was determined.
13p
trinhthamhodang1216
19-11-2020
10
1
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The present research was conducted to evaluate the effect of curcumin supplement diet (CSD) on non-specific immunity, growth and disease resistance against Edwardsiella tarda infection in Cirrhinus mrigala.
14p
angicungduoc8
07-11-2020
13
2
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The current study was conducted to find out the LD50 dose, shoot length and root length induced by both gamma rays and EMS in blackgram variety VBN 4, under laboratory condition. The investigation was carried out by exposing the seeds with different doses of gamma rays (10, 20, 30, 40, 50, 60, 70, 80 and 90kR) and various concentrations of EMS (30, 40, 50, 60 and 70mM) along with the control.
10p
chauchaungayxua8
03-10-2020
7
2
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The present investigation was taken up to study the sensitivity of two blackgram varieties viz., LBG 752 and TBG 104 to three mutagens on biological parameters and to determine the lethal dose (LD50) of mutagens.
13p
trinhthamhodang1215
23-09-2020
9
1
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Six strains of Beauveria bassiana were isolated from different sources collected from different places of Tamil Nadu and tested their efficacy under laboratory condition against crawler stages of papaya mealybug by insect dip bioassay method. The results revealed that B. bassiana strains, UPI (Bb) and ANR (Bb) were recorded the lowest LC50 values of 2.11 x106 , 2.37x107 spores ml-1 respectively which were indicated more virulence compared to other strains.
6p
kethamoi6
29-06-2020
6
1
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In the present studies treated the seeds using gamma rays different does 10 kR to 100 kR each treatment using 50 seeds. The percentage of seed germination ranges from 0 per cent to 52 per cent with different does of gamma rays in butter bean variety KKL-1 as compared to 86 per cent control. The different in seed germination are statistically significant. The LD50 value was found at 10 kR for seed germination. The percentage of survival was 81 per cent in control while it are significant range from 0 per cent 100 kR to 48 per cent 10 kR of gamma rays in butter bean variety KKL-1.
6p
chauchaungayxua6
26-06-2020
14
0
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Studies on mutagenic efficiency and effectiveness of sodium azide on Indian mustard in M2 generation
Mutagenic efficiency and effectiveness is an important factor for the selection of a mutagen for a mutation breeding program. The mutagenic efficiency gives an idea of the proportion of mutation on relation to the other associated undesirable biological effects such as lethality, sterility and meiotic aberrations while mutagenic effectiveness is a measure of the frequency of the mutation induced by unit dose of mutagens. The usefulness of any particular mutagen in crop breeding depends not only on its mutagenic effectiveness but also on the mutagenic efficiency of the mutagen.
4p
gaocaolon5
14-06-2020
16
1
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Evaluating the toxicity or effectiveness of two or more toxicants in a specific population often requires specialized statistical software to calculate and compare median lethal doses (LD50s).
10p
vimax2711
30-03-2020
15
1
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Concern about intoxication by e-liquid is growing as calls to poison control centers have increased since their introduction. Only three cases of intoxication by injection have been reported worldwide. Our case is unique because of the precise follow-up of a patient who survived a lethal dose of self-injected e-liquid, without other co-intoxication.
6p
vimax2711
27-03-2020
9
1
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New duck disease/ riemerellosis, caused by Riemerella anatipestifer, is a predominant disease affecting ducks, causing severe economic loss to the farmers of Kerala. However, the disease has also been reported from other birds. Ducks of all age groups are susceptible, but high mortality was observed in ducklings compared to adults.
5p
nguaconbaynhay4
22-03-2020
12
2
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In the present investigation, the mutagenic effectiveness and efficiency of different doses of a physical mutagen (gamma rays) were studied in clusterbean (Cyamopsis tetragonoloba (L) Taub) genotypes (viz. GST-15-204, RGC-1066, RCG-1055, RGC-1038. Ten different doses of gamma rays (viz. 5kR, 10kR, 15kR, 20kR, 25kR, 30kR, 35kR, 40kR 45kR and 50kR) were applied to. mutagenised the seeds of cluster bean genotypes.
10p
trinhthamhodang3
12-02-2020
17
1
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Pancreatic cancer has the highest mortality rate among cancers due to its aggressive biology and lack of effective treatment. Gemcitabine, the first line anticancer drug has reduced efficacy due to acquired resistance. The current study evaluates the toxicological effects of Orthosiphon stamineus (O.s) and its marker compound (rosmarinic acid) in combination with gemcitabine. O.s (200 or 400 mg/kg/day) and rosmarinic acid (32 mg/kg/day) were administered orally and gemcitabine (10 mg/kg/3 days) intraperitoneally either alone or in combination treatment for fourteen days.
10p
trinhthamhodang1
14-11-2019
9
1
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Efficacy of a baculovirus as a biological control agent is evaluated according to biological parameters, median lethal dose (LD50) of the virus, and median lethal time (LT50) of infected larvae.
5p
vivant2711
01-02-2019
32
1
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Apeptide called phaiodotoxin was isolated from the venom of the scorpionAnuroctonus phaiodactylus.It is lethal to crickets, but non toxic tomice at the doses assayed. It has 72 amino acid residues, with a molecular mass of 7971 atomic mass units. Its covalent structure was determined by Edman degradation and mass spectrometry; it contains four disul-fide-bridges, of which one of the pairs is formed between cysteine-7 and cysteine-8 (positions Cys63–Cys71). The other three pairs are formed between Cys13–Cys38, Cys23– Cys50 and Cys27–Cys52. ...
9p
awards
05-04-2013
41
2
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