Lines of Defence

This paper presents the main characteristics of the method, along with some practical guidelines to apply it to the specific case of the MSFR; moreover, some initiating events are analyzed through the implementation of the LoD tool. The outcomes of this analysis drive the design evolution.

11p christabelhuynh 29-05-2020 14 1   Download

Three pairs of parental (q + ) and established mitochondrial DNAdepleted (q 0 ) cells, derived frombone, lungandmuscle were used to verify the influence of the nuclear background and the lack of efficient mitochondrial respiratory chain on antioxidant defences and homeostasis of intracellular reactive oxygen species (ROS).

11p awards 05-04-2013 45 4   Download

Collectins are effector molecules of the innate immune system that play an important role in the first line of defence against bacteria, viruses and fungi. Most of their interactions with microorganisms are mediated through their carbohydrate recognition domain (CRD), which binds in a Ca 2+ -dependent manner to glycoconjugates. Molecular

12p cosis54 09-12-2012 34 2   Download