Liquid chromatography – mass spectrometry

Red yeast rice is produced from rice using Monascus purpureus fungus, which results in the red colour of the fermented rice. Red yeast rice has been used for a thousand years as a food preservative and in traditional medicine to support vascular and digestive health. This study used Liquid Chromatography-Mass Spectrometry (LC-MS/MS) to concurrently analyse citrinin and monacolin K produced by M. purpureus strain.

11p viaburame 14-03-2025 1 1   Download

Carvedilol is a pharmaceutical substance listed in the “Regulatory requirements of bioequivalence study reports for generic drugs containing APIs upon applying for marketing authorization”. Therefore, a simple method for quantifying carvedilol in human plasma is desirable.

6p vihatake 06-01-2025 3 2   Download

The objects of the thesis: Study and develop the simultaneous analysis method of plant growth stimulants in vegetables using by high-performance liquid chromatography coupled with ion-trapping mass spectrometry. Apply the studied method of analysis and assessment of the current use, residue level and the potential accumulation of plant growth stimulants used in vegetable production in several districts belonged to Hanoi.

28p extraenglish 24-05-2021 16 3   Download

AR-42, a new orally bioavailable, potent, hydroxamate-tethered phenylbutyrate class I/IIB histone deacetylase inhibitor currently is under evaluation in phase 1 and 2 clinical trials and has demonstrated activity in both hematologic and solid tumor malignancies. This report focuses on the preclinical characterization of the pharmacokinetics of AR-42 in mice and rats.

9p caothientrangnguyen 09-05-2020 20 3   Download

Peptides which should be generated from the neuropeptide FF (NPFF) precursor were identified in a neuronal (human neuroblastoma SH-SY5Y) cell line and in COS-7 cells after transient transfection of the human proNPFFAcDNA and were comparedwith those detected in themouse spinal cord. After reverse-phase high performance liquid chromatogra-phy of soluble material, NPFF-related peptides were im-munodetected with antisera raised against NPFF and identified by using on-line capillary liquid chromatography/ nanospray ion trap tandem mass spectrometry. ...

13p tumor12 20-04-2013 33 3   Download

Liquid chromatography mass spectrometry (LC-MS) is a valuable tool in the analysis of proteins and peptides.The combination of LC-MS with different fragmentation methods provides sequence information on components in complex mixtures.In this work, on-line packed capillary LC electrospray ionization Fourier transform ion cyclotron resonance MS was combined with two complementary fragmentation techniques, i.e.

7p tumor12 20-04-2013 49 2   Download

Limited proteolysis in combination with liquid chromatography-ion trap mass spectrometry (LC-MS) was used to analyze engineered or natural proteins derived from a type I modular polyketide synthase (PKS), the 6-deoxyerythronolide B synthase (DEBS), and comprising either the first two extension modules linked to the chain-terminating thioesterase (TE) (DEBS1-TE); or the last two extension modules (DEBS3) or the first exten-sion module linked to TE (diketide synthase, DKS).

15p awards 06-04-2013 38 1   Download

A platform based on hydrophilic interaction chromatography in combina-tion with Fourier transform mass spectrometry was developed in order to carry out metabonomics of Drosophila melanogasterstrains. The method was able to detect230 metabolites, mainly in the positive ion mode, after checking to eliminate false positives caused by isotope peaks, adducts and fragment ions.

12p viettel02 20-02-2013 42 3   Download

Background: Pancreatic cancer is one of the most aggressive human tumors due to its high potential of local invasion and metastasis. The aim of this study was to characterize the membrane proteomes of pancreatic ductal adenocarcinoma (PDAC) cells of primary and metastatic origins, and to identify potential target proteins related to metastasis of pancreatic cancer.

13p toshiba23 18-11-2011 80 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Comparison of raw and processed Radix Polygoni Multiflori (Heshouwu) by high performance liquid chromatography and mass spectrometry...

9p thulanh18 28-10-2011 47 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Quality evaluation of mycelial Antrodia camphorata using high-performance liquid chromatography (HPLC) coupled with diode array detector and mass spectrometry (DAD-MS)...

6p thulanh18 28-10-2011 50 3   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Quasi-MSn identification of flavanone 7-glycoside isomers in Da Chengqi Tang by high performance liquid chromatography-tandem mass spectrometry...

10p thulanh18 28-10-2011 59 6   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Determination of Roxithromycin by Liquid Chromatography/ Mass Spectrometry after Multiple-Dose Oral Administration in Broilers

5p hoami_266 16-09-2011 48 2   Download

Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Simultaneous Determination of Various Macrolides by Liquid Chromatography/Mass Spectrometry

6p hoami_266 15-09-2011 47 3   Download