Liver transaminases

Hyperbilirubinemia and transaminitis are rarely associated with a disorder of endocrine function. It mostly manifests as a cholestatic pattern of liver injury. Herein, a 25-year-old female patient with a past medical history of congenital hypopituitarism due to pituitary ectopia presented with serum direct bilirubin level of 9.9 mg/dL and aspartate transaminase (AST)/alanine transaminase (ALT) of 60/47 U/L.

4p viwhitewolf 03-07-2023 8 2   Download

RAD140 (Testalone) is a novel selective androgen receptor modulator with very limited data currently available on adverse effects related to this compound. The first-in-human phase 1 trial was recently published and did report a significant proportion of elevated aspartate aminotransferase, alanine transaminase, and total bilirubin among the test subjects.

3p vidoctorstrange 06-05-2023 3 2   Download

Liver function is routinely assessed in clinical practice as liver function tests provide sensitive indicators of hepatocellular injury. However, the prognostic value of enzymes that indicate hepatic injury has never been systematically investigated in lymphoma, including diffuse large B-cell lymphoma (DLBCL).

9p vikuala271 13-06-2020 13 1   Download

A 21-year-old man from India presented with acute hepatitis associated with a 1-week history of abdominal pain, pruritus, and dark urine. Over a 7-day admission, the patient’s acute hepatitis evolved into acute liver failure with low-grade encephalopathy, markedly elevated transaminases, bilirubin, and impaired hepatic synthetic function. He was eventually diagnosed with acute hepatitis E virus (HEV) and was transitioned to supportive management. Acute HEV is a rare cause of acute liver failure.

3p covid19 11-05-2020 17 1   Download

These preliminary findings suggest that Hispanic children with T2DM may be at higher risk for developing non-alcoholic fatty liver disease and indicate that a comprehensive hepatic evaluation is warranted in this population. Future studies that incorporate more precise and proximal measures of liver health are warranted in this population.

6p vivalanbo2711 19-03-2020 11 0   Download

Serum transaminases provide modest predictive value for hepatic steatosis in youth. The ALT threshold for predicting hepatic steatosis is significantly lower than current clinical thresholds for predicting non-alcoholic fatty liver disease.

8p vichengna2711 25-02-2020 15 0   Download

Dengue infections are currently one of the most rapidly emerging arboviral infections in the world. There is high mortality associated with severe dengue infection so we conducted study to predict various factors indicating severity of dengue infection. This cross- sectional study conducted in tertiary care hospital of central India. Data associated with various clinical features of dengue infection collected in predesigned questionnaire.

6p chauchaungayxua3 07-02-2020 7 0   Download

Series of biochemical and haematological changes occur during the course of dengue infection, which vary depending on the clinical disease. The patterns of change are not well documented and identifying these patterns in children with dengue infection would help to anticipate the progression to different clinical stages thus enabling effective management.

9p vidublin2711 13-01-2020 12 1   Download

The in vitro total antioxidant and anti-inflammatory capacity of the methanol extract of Ixora duffii leaf (―Trang to‖ in Vietnamese) was investigated using the phosphomolypdenum method and the bovine serum albumin denaturation test, respectively. The results showed that the methanol extract of I. duffii leaf possessed relatively high antioxidant activity (OD0,5 = 15.551 ± 0.344 μg/mL) compared to that of the standard, trolox (OD0,5=2.315 ± 0.083 μg/mL). The antiinflammatory effect using bovine serum albumin denaturation test showed that the activity of the methanol extract of I.

12p gaunguyen6789 22-10-2019 26 2   Download

The effects of the LD30 (20 mg.kg-1) dose of paraquat, a herbicide, were investigated on creatine kinase (CK), glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), lactate dehydrogenase (LDH) and gamma glutamyl transferase (GGT) activities in the liver, kidney and lung of mice after 2, 4, 8, 16, 32, 64 and 72 hours.

10p caplock2711 19-02-2019 13 0   Download

Bài giảng Liver tests trình bày các kiến thức đại cương về gan và tổn thương gan, bệnh gây tăng Aminotranserase, thuốc gây tăng aminotranserase, nguyên nhân ít gặp gây tăng transaminases, đánh giá bệnh nhân tăng AST & ALT nhẹ trung bình,... Mời các bạn cùng tham khảo nội dung chi tiết.

33p nhansinhaomong_02 04-10-2015 61 5   Download