MBL producing Pseudomonas aeruginosa

This study was taken up, to compare different phenotypic tests for identification of producing P. aeruginosa from pus samples. This possibly will help to prevent the associated morbidity and mortality caused due to this organism by implementing proper control measures and to evaluate antibiotic therapy.

8p cothumenhmong9 04-01-2021 9 1   Download

Resistance to carbapenems are because of various mechanisms like mutations in the outer membrane proteins like Opr D causing decreased permeability of the drugs, the carbapenem hydrolyzing enzymes–carbapenemases and the efflux mechanisms. Carbapenem resistance was studied in 140 non-repeat clinical isolates of Pseudomonas aeruginosa in a tertiary care hospital. Imipenem resistance was detected using Kirby Bauer’s standard disc diffusion method. MIC for Imipenem was detected in all resistant isolates using E-test strips.

7p chauchaungayxua6 26-06-2020 14 2   Download

This situation prompts early and accurate detection of MBL producers. Hence the present study was done to phenotypically evaluate the prevalence of MBL production among 235 clinical isolates of Pseudomonas aeruginosa (183) and Acinetobacter species (52). The antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion method.

11p trinhthamhodang5 16-05-2020 13 1   Download

The present study was done to detect Extended spectrum β lactamase and metallo-βlactamase producing isolates of Pseudomonas aeruginosa from various clinical samples from patients admitted in Tirunelveli Government medical college hospital. In this study we studied the prevalence of ESBL and MBL among 112 Pseudomonas aeruginosa isolates, following standard methods of isolation and identification of these bacteria from clinical materials

8p kethamoi4 18-04-2020 15 0   Download

In recent decades the global emergence the development of multidrug-resistant and pan drug resistance in Pseudomonas aeruginosa has been observed. This opportunistic pathogen is responsible for causing various infections especially in the intensive care units, resulting for almost 10% of nosocomial infections. The resistance to Metallo betalactamase in P. aeruginosa strains has been related with bacterial biofilm formation. So, the aim of this study was to determine the rates of biofilm production and metallo betalactamase production (MBL) among the strains of Pseudomonas aeruginosa.

6p trinhthamhodang3 22-02-2020 8 0   Download

Metallo beta-lactamase (MBL) and biofilm production is the most worrisome resistant mechanisms observed in Pseudomonas aeruginosa. Increased resistance of Pseudomonas to antibiotic therapy is an emerging global health concern which can be overcomed by Silver nanoparticles (AgNPs). Therefore this study aims to evaluate the antibacterial and antibiofilm activity of Silver nanoparticles on MBL and biofilm producing P. aeruginosa isolates using Transmission Electron microscope (TEM) and Confocal laser scanning microscope (CLSM) respectively. A total 40 isolates of p.

18p chauchaungayxua3 07-02-2020 11 0   Download

NFGNB also known as Non-fermenters (NFs) are emerging with increasing frequency as agents of opportunistic and often, serious infection as well as nosocomial infection. NFGNB are innately resistant to many antibiotics and are known to produce extended spectrum β-lactamases and metallo β-lactamases (MBL).Very few laboratories in India identify these organisms as routine as they are slow growing and requires special media and biochemical tests for identification. The rates of isolation of NFGNBs are increasing in Clinical Microbiology Laboratory, hence this study was done.

10p nguaconbaynhay3 07-02-2020 24 1   Download

One of the common causes of morbidity and mortality following burn injury is infections. The emergence of metallo-β-lactamase (MBL) in Gram negative bacilli (GNB) has reduced the available therapeutic options for effective treatment. Therefore, for screening of carbapenemase producers, a simple and inexpensive testing method is essential. To know the prevalence of MBL production in various gram negative isolates, to evaluate different phenotypic methods to detect MBL production and to find out antibiotic sensitivity profile of MBL producing gram negative bacilli.

9p quenchua2 15-12-2019 14 0   Download

Metallo-beta-lactmase producing Pseudomonas aeruginosa strains are responsible for several nosocomial outbreaks in tertiary care centres across the world. It is well known that poor outcome occurs when patients with serious infections due to MBL producing organisms are treated with antibiotics to which the organism is completely resistant. Therefore, detection of MBL producing Pseudomonas aeruginosa strains is crucial for optimal treatment of critically ill patients and to prevent the spread of resistance.

6p kethamoi2 15-12-2019 18 0   Download