Measure telomere length

Esophageal cancer is the sixth leading cause of cancer death worldwide; current early detection screening tests are inadequate. Esophageal balloon cytology successfully retrieves exfoliated and scraped superficial esophageal epithelial cells, but cytologic reading of these cells has poor sensitivity and specificity for detecting esophageal squamous dysplasia (ESD), the precursor lesion of esophageal squamous cell carcinoma (ESCC).

8p vijennie2711 29-09-2020 27 1   Download

Telomere comprises of TTAGGG repeats and its lack of functionality results in promoting cancer through driving genetic instability. It is evident that they protect chromosomal ends and conserve our genetic information. This review discusses various laboratory methods of telomere length measurement.

6p nguaconbaynhay7 15-08-2020 6 0   Download