Metabolic activities

Peroxisome proliferator-activated receptor gamma (PPARG) is a member of the nuclear receptor family. It is involved in the regulation of adipogenesis, lipid metabolism, insulin sensitivity, vascular homeostasis and inflammation.

12p vikoch 27-06-2024 1 1   Download

This study aims to identify functionally relevant lncRNAs impacting OS proliferation and lipid metabolism and seeks to shed light on the upstream regulatory mechanisms governing lipogenic enzyme activity. Based on comprehensive bioinformatic analysis and the establishment of a risk model, we identified seven lncRNAs signifcantly associated with clinical characteristics and lipid metabolism-related genes in patients with OS.

15p vikoch 27-06-2024 1 1   Download

Positron emission tomography (PET) is a type of nuclear medicine procedure that measures the metabolic activity of cells in body tissues that is well suited for detecting, staging and monitoring malignant tumours. In this paper, the authors have successfully developed the application based on the algorithm that they proposed.

10p viambani 18-06-2024 2 1   Download

This study implicated the soft coral-associated Micrococcus sp. strain A-2-28 (following relative Micrococcus flavus LW4T) for large-scale cultivation, chemical analyses, and biological activities. Whereas crude extract of the strain A-2-28 inhibited only Staphylococcus epidermidis, metabolites profiles and pure compounds from strain A-2-28 showed that this strain produced phytohormone (IAA), metabolized some new compounds which were almost inactive for biological tests.

8p dianmotminh02 03-05-2024 3 1   Download

Oxidoreductases (ORases) are enzymes that catalyze oxidation and reduction reactions in cells or extracellular compartments of the body. Genetic mutations and other factors that affect ORase activity have been implicated in a range of diseases, especially inherited metabolic disorders. Aldose reductase, sorbitol dehydrogenase, xanthine oxidoreductase are the ORases with relevance to diabetes pathology.

7p dianmotminh02 03-05-2024 3 1   Download

Ebook "Mitochondria and cancer" presents thorough analyses of mitochondrial dysfunction as one of the hallmarks of cancer, discusses the clinical implications of mitochondrial defects in cancer, and as unique cellular targets for novel and selective anti-cancer therapy. These include differences in mitochondrial metabolic activity, molecular composition of mitochondria and mtDNA sequence, as well as in alteration of nuclear genes encoding mitochondrial proteins.

294p ladongphongthanh1008 22-04-2024 3 1   Download

Ebook "CtBP family proteins" are unique in several aspects. They were the first among proteins containing a metabolic enzyme fold to be implicated in transcriptional regulation. The vertebrate CtBPs exhibit distinct nuclear and cytosolic activities. The crystal struaures of CtBPl and molecular modeling studies have illuminated the molecular basis of its dual activity and the interaction with target peptides.

131p ladongphongthanh1008 22-04-2024 5 2   Download

Ebook "Flow chemistry for the synthesis of heterocycles" provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis. The heterocyclic ring is the most prominent structural motif in the vast majority of natural products as well as pharmaceutical compounds since this facilitates tuneable interactions with the biological target besides conferring a degree of structural and metabolic stability.

400p tracanhphuonghoa1007 22-04-2024 4 3   Download

Ebook "Small molecule therapeutics for schizophrenia" covers all relevant aspects of drug research, e.g.

327p tracanhphuonghoa1007 22-04-2024 3 3   Download

Part 1 book "Fungal biology" includes content: Introduction - The fungi and fungal activities; the diversity of fungi and fungus -like organisms; fungal structure and ultrastructure; fungal growth; differentiation and development; fungal nutrition; fungal metabolism and fungal products; environmental conditions for growth and tolerance of extremes.

166p muasambanhan10 11-04-2024 1 1   Download

Links between colorectal cancer (CRC) and the gut microbiome have been established, but the specific microbial species and their role in carcinogenesis remain an active area of inquiry. Our understanding would be enhanced by better accounting for tumor subtype, microbial community interactions, metabolism, and ecology.

13p vibransone 28-03-2024 3 2   Download

The liver X receptors (LXRs, NR1H2 and NR1H3) and peroxisome proliferator-activated receptor gamma (PPARG, NR1C3) nuclear receptor transcription factors (TFs) are master regulators of energy homeostasis. Intriguingly, recent studies suggest that these metabolic regulators also impact tumor cell proliferation.

16p vioraclene 31-03-2024 5 2   Download

The interaction between the metabolic activities of the intestinal microbiome and its host forms an important part of health. The basis of this interaction is in part mediated by the release of microbially-derived metabolites that enter the circulation.

13p viellison 28-03-2024 5 2   Download

Ebook "Epigenetics in plants of agronomic importance: Fundamentals and applications (Transcriptional regulation and chromatin remodelling in plants)" provides a detailed understanding of the epigenetic mechanisms involved in plants of agronomic importance. The information presented here is significant because it is expected to provide the knowledge needed to develop in the future treatments to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases and to increase crop productivity.

158p manmanthanhla0201 26-02-2024 5 1   Download

Ebook "Nitric oxide in plants: Metabolism and role in stress physiology" covers the key features of nitric oxide (NO) in plants. Comprising nine chapters, Part I highlights its metabolism and identification in plants. Part II, which consists of eight chapters, focuses on the chemical, physical and biochemical properties of the NO molecule and its derivatives; on its functional role and mode of action; and on its signaling and interaction with phytohormones, mineral nutrients, biomolecules, ions and ion channels in plants under abiotic stresses.

310p manmanthanhla0201 26-02-2024 3 1   Download

Ebook "Tactics in contemporary drug design" covers all relevant aspects of drug research, e.g.

400p manmanthanhla0201 26-02-2024 2 1   Download

Ebook "DNA replication control in microbial cell factories" describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested.

56p manmanthanhla0201 27-02-2024 4 1   Download

Part 2 book "Molecular cell biology" includes content: Post transcriptional gene control and nuclear transport, signaling at the cell surface, signaling pathways that control gene activity, integration of signals and gene controls, moving proteins into membranes and organelles, vesicular traffic, secretion and endocytosis, metabolism and movement of lipids, microfilaments and intermediate filaments, microtubules, regulating the eukaryotic cell cycle, cell birth, lineage and death, cancer.

477p muasambanhan07 18-02-2024 5 1   Download

Diabetes is a type of metabolic disorder, which is the cause of many dangerous complications. Ensete glaucum (Musaceae family) has active ingredients with antioxidant and hypoglycemic characteristics in some parts of the plant. This study investigates the ability to reduce blood sugar based on the inhibition of αamylase and α-glucosidase enzymes of Ensete glaucum stem extract.

13p vigojek 02-02-2024 2 1   Download

Ebook "The blood brain barrier (BBB)" covers all relevant aspects of drug research, e.g.

169p nhanphanguyet 28-01-2024 5 2   Download