Minimum inhibitory concentration (MIC)

Bài viết trình bày xác định tỷ lệ đề kháng kháng sinh nhóm Beta- lactam và Quinolone của vi khuẩn Enterobacteriaceae; tỷ lệ đề kháng Colistin của chủng vi khuẩn Pseudomonas aeruginosa; Xác định Minimum Inhibitory Concentration (MIC) của Colistin bằng phương pháp Broth disk elution trên vi khuẩn Enterobacteriaceae đề kháng Beta- lactam và Quinolone; vi khuẩn Pseudomonas aeruginosa đề kháng Colistin trên máy kháng sinh đồ tự động.

7p visybill 19-07-2023 5 2   Download

This study aims to provide an in vitro evidence for the potential antibacterial activity of the ethanolic and aqueous extracts from fruiting bodies of the Pycnoporus sanguineus (L.: Fr.) Murrill mushroom via agar well diffusion method (concentration of extracts 250 mg/mL) and determination of the antibacterial activity and minimum inhibitory concentrations (MIC) of ethanolic and aqueous extracts from the fruiting bodies of this mushroom by agar dilution method (concentration range of 25; 12.5; 6.25; 3.125 and 1.5625 mg/mL).

8p viporsche 28-10-2022 6 2   Download

Nghiên cứu này xác định thành phần hóa học chính, nồng độ ức chế tối thiểu vi khuẩn phân lập (Minimum Inhibitory Concentration - MIC), nồng độ diệt khuẩn tối thiểu (Minimum Bactericidal Concentration - MBC), và nồng độ diệt nấm tối thiểu (Minimum Fungicidal Concentration - MFC) của tinh dầu 4 loài trong chi Ocimum, họ Hoa Môi (Lamiaceae): é trắng (Etr), húng quế (HQ), hương nhu trắng (HNTr) và hương nhu tía (HNT).

6p vihassoplattner 04-01-2022 39 0   Download

Inhibitory effect of oil and its preparations were studied using disc-diffusion and Minimum Inhibitory Concentration (MIC) tests, and using corn oil and Streptomycin as controls.

6p schindler 30-12-2021 14 0   Download

A series of binucleating Cu(II), Ni(II), and Zn(II) complexes of bicompartmental ligands with ONO donors were prepared. The ligands were synthesized by the condensation of 5-substituted-3-phenyl-1H -indole-2-carboxyhydrazides and 4,6-diacetylresorcinol. The newly synthesized ligands and their complexes were characterized by elemental analysis and various spectral studies like IR, 1H NMR, ESI-mass, UV-Vis, ESR, thermal studies, magnetic susceptibility, molar conductance, and powder-XRD data.

21p langthannam 29-12-2021 8 0   Download

The newly synthesized compounds were screened for their antimicrobial activities; some of them were found to be active towards the test microorganisms as the results demonstrated that the synthesized compounds exhibited a broad spectrum of activity with minimum inhibitory concentration (MIC) values of 31.3–500 µg/mL against gram-positive and gram-negative bacteria, Candia albicans and Saccharomyces cerevisiae.

12p langthannam 29-12-2021 8 0   Download

This study was the first fatty acid analysis and biological activity report on an endemic Achillea species, Achillea cappadocica Hausskn. et Bornm. The major compounds in the fatty acid were identified as oleic (34.7%), palmitic (23.1%), and linoleic acids (20.6%). The methanol and water extracts indicated higher ABTS cation radical scavenging activity than that of α-tocopherol and BHT at 100 µg/mL. The acetone extract showed 70.62% inhibitory activity against butyrylcholinesterase at 200 µg/mL. The acetone and methanol extracts exhibited moderate antimicrobial activity.

8p langthannam 29-12-2021 17 0   Download

The new compounds 7a–k, 8a–k, and 9a–k were synthesized from flavonones 4–6, which can be considered new precursors for quinoline synthesis through a one-step reaction. All the target compounds (7a–k, 8a–k, and 9a–k) were evaluated for their in vitro antimicrobial activity against nine test microorganisms. They showed the most activity against Mycobacterium smegmatis with minimum inhibitory concentrations (MIC) of 62.5–500 µg/mL, indicating their potential uses as antituberculosis agents. Among them 8a–k (m-fluoride) were the most active compounds against M. smegmatis (MIC, 62.5–125 µg/mL).

17p langthannam 29-12-2021 11 0   Download

The aim of this study was to evaluate the antimicrobial activity of three commercial GSE (Grapefruit Seed Extract) products against six bacterial and one fungal strain, through the agar well diffusion method, determination of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentration (MFC). Obtained results indicate strong antimicrobial effects of investigated extracts, with different microbial susceptibility, including the multidrug-resistant (MDR) bacteria.

4p mudbound 10-12-2021 10 1   Download

The present study aimed to synthesize ursolic acid-loaded chitosan nanoparticles (UA-Ch-NPs) as an antiinfective agent against 21 Staphylococcus aureus isolates. The UA-Ch-NPs were synthesized by a simple method and then characterized by TEM, FTIR, DLS-zeta potential, and XRD analyses. According to the characterization results, highly dispersed spherical nanoparticles with a mean diameter of 258 nm and a zeta potential of + 40.1 mV were developed. The antibacterial properties of UA-Ch-NPs were investigated and their inhibitory effect on biofilm formation was demonstrated by AFM.

9p tudichquannguyet 29-11-2021 9 2   Download

Twenty-two compounds in a series of 1-(benzo[ b ]thiophen-4-yl)-4-(2-(oxo, hydroxy, and fluoro)-2-phenylethyl) piperazine and 1-(benzo[d]isothiazole-3-yl)-4-(2-(oxo, hydroxy, and fluoro)-2-phenylethyl)-piperazine derivatives were synthesized through nucleophilic substitution reaction of phenacyl bromides with hetero arylpiperazine, reduction, and then fluorination. Compound K2 showed potent activity against gram-negative bacterial stain P. aeruginosa with minimum inhibitory concentration (MIC) value of 12.5 µg/mL.

50p tudichquannguyet 29-11-2021 10 1   Download

Plants are the main source of drugs nowadays. They provide a high benefit to risk ratio. Naringenin is a plant flavonoid obtained from citrus fruits. It exhibits plethora of effects against a number of diseases. Agar dilution method was used to evaluate minimum inhibitory concentration (MIC) naringenin and three β-lactam drugs amoxicillin, oxacillin and cloxacillin. Checkerboard method was used to determine the fractional inhibitory concentration (FIC) of the drugs in combination with naringenin.

11p cothumenhmong11 11-05-2021 8 1   Download

Mục đích nghiên cứu của luận văn nhằm sàng lọc hoạt tính kháng khuẩn các chủng vi khuẩn chuẩn gây bệnh đường hô hấp của hai loại tinh dầu húng quế lá lớn và lá nhỏ. Xác định giá trị MIC (Minimum Inhibitory Concentration) và MBC (Minimum Bactericidal Concentration) của tinh dầu trên các chủng vi khuẩn chuẩn.

61p mucnang888 16-04-2021 75 13   Download

The present study was undertaken to determine the current minimum inhibitory concentration of halquinol against bacterial pathogens of poultry origin so as to find its suitability for treating infections by such pathogens in poultry.

4p caygaocaolon7 18-09-2020 14 0   Download

The objective of this study is to isolate and screen fungal strains with antibacterial activity from the marine environment. Twenty five strains of fungi were isolated from marine sediments of Thanh Lan, Co To island and assessed on antibiotic activity against 7 tested microbial strains, including three Gram-negative bacteria (Escherichia coli ATCC25922, Pseudomonas aeruginosa ATCC27853, Salmonella enterica ATCC13076), three Gram-positive bacteria (Enterococcus faecalis ATCC29212, Stapphylococus aureus ATCC25923, Bacillus cereus ATCC 13245), and the yeast Candida albicans ATCC10231.

8p nguyenxuankha_bevandan 14-08-2020 37 3   Download

Antifungal activities of the three mushrooms Pleurotus pulmonarius, Pleurotus florida and Schizophyllum commune ethanol extracts were evaluated against some plant pathogenic fungi (Aspergillus flavus, Aspergillus niger and Alternaria solani, Colletotrichum graminicola, Fusarium oxysporum) by using agar well diffusion method. Minimum inhibitory concentration (MIC) was investigated for 1-20 mg/ml concentration to find out the lowest concentration of the sample that inhibits the growth of the test organisms.

8p angicungduoc6 22-07-2020 15 1   Download

Escherichia coli (E. coli) is one of most common organisms responsible for health careassociated urinary tract infection (HAUTI). The aim of this study was to determine antibiotic susceptibility pattern of E. coli isolated from HAUT I and to study ciprofloxacin resistance caused by gyrA gene mutations among these isolates. Urine Samples were collected from patients with suspected HAUTI. E. coli identification and antimicrobial susceptibility testing, minimum inhibitory concentration (MIC) of ciprofloxacin were done followed by detection of mutations in the gyrA gene by PCR-RFLP.

6p nguaconbaynhay6 24-06-2020 10 0   Download

Honey has been used for various purposes including treatment of some diseases locally especially in wounds and upper respiratory tract infections (URTIs). There is paucity of information on the scientific basis for the use of honey in the treatment of upper respiratory tract infections caused by bacteria. This study was carried out to determine antibacterial activities of different brands of honey marketed in Ado-Ekiti and relate with those of some orthodox antibiotics used in the treatment of URTIs.

10p nguaconbaynhay6 24-06-2020 12 1   Download

The investigation was aimed at to proximate the minimum inhibitory concentration (MIC) of 2-nitropropanol (2-NPOH) for growth inhibition (in-vitro) of Salmonella typhimurium, Shigatoxic Escherichia coli (STEC) and Salmonella gallinarum vis a vis effect of pH of culture medium on function of 2-NPOH and its in-vivo effect on these bacteria in chick model. In in-vitro testing, MIC of 2-NPOH for Salmonella typhimurium was recorded to be 3.5 mM whereas it was 1.5 mM for STEC and Salmonella gallinarum.

8p quenchua6 15-06-2020 11 1   Download

The objective of this study was to determine the minimum inhibitory concentration (MIC) of crude extract from five medical herbs in Vietnam (Camellia sinensis, Eclipta prostrata L., Pseuderanthemum palatiferum, Psidium guajava, Azadirachta indica) against Escherichia coli ATCC25922, Salmonella Typhimurium, Staphylococcus aureus ATCC25923 by macro - dilution method

6p tomhiddleston 25-05-2020 8 0   Download