Neurodegenerative diseases
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Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens resulting in degeneration of Purkinje neurons in the cerebellum.
16p vikoch 27-06-2024 1 1 Download
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Part 2 book "Rang and Dale's pharmacology" includes content: Respiratory system; the kidney, the gastrointestinal tract, the control of blood glucose and drug treatment of diabetes mellitus, obesity, the pituitary and the adrenal cortex, the thyroid, the reproductive system, bone metabolism, chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases,... and other contents.
442p dianmotminh03 03-06-2024 1 0 Download
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Ebook "Protein folding and misfolding: Neurodegenerative diseases" is to review the molecular events initiated by unfolded or misfolded proteins leading to cell death via the development of pathological inclusions, with special emphasis on the macromolecular associations of the malfolded proteins into characteristic ultrastructures found in the cases of neurological disorders, some of them are shown in this issue.
284p ladongphongthanh1008 22-04-2024 3 2 Download
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Ebook "The proteasome in neurodegeneration" will be of relevance for many years to come, and are intended to generate interest in the nuances of the UPS system, and highlight new avenues for the understanding of the UPS and the generation of UPS-based therapies for the treatment of neurodegenerative diseases.
314p ladongphongthanh1008 22-04-2024 4 2 Download
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Ebook "Stem cells in modeling human genetic diseases" examples of the use of iPS cell technology, a recent Nobel Prize-winning scientific breakthrough, to obtain patient-specific pluripotent cells from which many types of specialized cells involved in a particular disease can be generated, including psychiatric and neurodegenerative disorders, muscular dystrophies, laminopathies, among others.
157p ladongphongthanh1008 22-04-2024 6 2 Download
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Ebook "Emerging trends in chemical sciences" provides readers with contents including: glucagon by the gut peptide, GLP-1 - controversies, challenges and future directions; analysis of non-conducting tantalite minerals by glow discharge optical emission spectrometry; chemical composition and antioxidant activity of tagetes minuta L. in Eastern Cape, South Africa;...
418p tracanhphuonghoa1007 22-04-2024 5 2 Download
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Knowledge of the molecular etiology of neurodegenerative brain diseases (NBD) has substantially increased over the past three decades. Early genetic studies of NBD families identified rare and highly penetrant deleterious mutations in causal genes that segregate with disease.
13p vibransone 28-03-2024 3 2 Download
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Alzheimer’s disease (AD) is an incurable neurodegenerative disease currently affecting 1.75% of the US population, with projected growth to 3.46% by 2050. Identifying common genetic variants driving differences in transcript expression that confer AD risk is necessary to elucidate AD mechanism and develop therapeutic interventions.
15p vibransone 28-03-2024 2 2 Download
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Amyotrophic lateral sclerosis (ALS) is a complex, late-onset, neurodegenerative disease with a genetic contribution to disease liability. Genome-wide association studies (GWAS) have identified ten risk loci to date, including the TNIP1/GPX3 locus on chromosome five.
22p vibransone 28-03-2024 3 1 Download
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The Colombian population, as well as those in other Latin American regions, arose from a recent tricontinental admixture among Native Americans, Spanish invaders, and enslaved Africans, all of whom passed through a population bottleneck due to widespread infectious diseases that left small isolated local settlements.
22p viellison 28-03-2024 2 2 Download
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Wolfram syndrome is a rare autosomal recessive neurodegenerative disorder that affects 1/200,000 to 1/1,000,000 children. It is characterized by juvenile onset diabetes, optic nerve atrophy and other systemic manifestations. Symptoms of the disease arise mostly in early childhood with a high mortality rate due to severe neurological complications.
5p vitiki 30-01-2024 7 2 Download
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Part 2 book "Rang and Dale's pharmacology" includes content: Chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases, general anaesthetic agents, analgesic drugs, local anaesthetics and other drugs affecting sodium channels, anxiolytic and hypnotic drugs, antiepileptic drugs, antipsychotic drugs, antidepressant drugs, psychoactive drugs, drug abuse and dependence
348p muasambanhan05 22-01-2024 4 2 Download
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Ebook "Induced pluripotent stem cells in brain diseases: Understanding the methods, epigenetic basis, and applications for regenerative medicine" discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).
69p tachieuhoa 28-01-2024 2 2 Download
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Ebbok "Advances in stem cell therapy: Bench to bedside" reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals.
319p lamquandat 28-12-2023 3 2 Download
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Carpal tunnel syndrome (CTS) is one of the most common neurodegenerative conditions. However, studies on the classifications and symptoms of CTS from the perspective of traditional medicine are still limited. Our study aims to identify traditional medicine disease nomenclature and symptoms of CTS by the survey form.
12p vikissinger 21-12-2023 3 1 Download
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MicroRNAs (miRNAs) are small non-coding RNAs that play a crucial role in regulating gene expression post-transcriptionally. These molecules have been implicated in various diseases, including cancer, viral infections, cardiovascular disorders, and neurodegenerative conditions. This study introduces a novel approach for predicting miRNA-disease associations by leveraging heterogeneous graph representation learning.
10p visharma 20-10-2023 4 2 Download
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Niemann-Pick type A (NP-A) is a congenital, hereditary disease caused by a deficiency in acid sphingomyelinase, a lysosomal enzyme. This deficiency results in an accumulation of sphingomyelin in lysosomes, leading to cellular apoptosis and ultimately to hepatosplenomegaly, neurodegenerative disorder and failure to thrive.
4p vigamora 23-05-2023 8 2 Download
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Multiple sclerosis (MS) is a complex disorder of the central nervous system whose cause is currently unknown. Evidence is increasing that DNA methylation alterations could be involved in inflammatory and neurodegenerative diseases and could contribute to MS pathogenesis.
7p vinarcissa 21-03-2023 4 1 Download
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There has been considerable interest in discovery of the genetic architecture of complex traits, particularly age-related neurodegenerative disorders. To predict disease risk and to understand its genetic basis in humans, it is necessary to study animal models.
17p vinarcissa 21-03-2023 3 1 Download
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Cerebellar cortical degeneration (CCD) is an increasingly recognised neurodegenerative disease process affecting many dog breeds. Typical presentation consists of a progressive cerebellar ataxia, with a variable age at onset and rate of progression between different breeds.
8p vinarcissa 21-03-2023 1 1 Download