Nicotine dependence

The study was conducted to determine the prevalence of adolescent smoking in Hanoi city in 2023 and the perception of adolescents toward adverse impacts of tobacco. The piece of research was a cross-sectional study, using quantitative methods.

8p vigeorge 06-12-2023 2 1   Download

This study investigated whether polymorphisms of the ankyrin repeat and kinase domain containing 1 gene (ANKK1), which is adjacent to the dopamine D2 receptor gene (DRD2), and the dopamine transporter (SLC6A3) and cytochrome P450 2A6 (CYP2A6) genes influence smoking cessation and nicotine dependence in a Japanese population.

9p vinarcissa 21-03-2023 2 1   Download

The aim of this study was to determine if variable number of tandem repeats (VNTR) in the second intron (STin2) of the serotonin transporter (SLC6A4) gene was associated with tobacco use disorder, successful smoking cessation, or smoking characteristics.

9p vinarcissa 21-03-2023 1 1   Download

Cox-regression-based methods have been commonly used for the analyses of survival outcomes, such as age-at-disease-onset. These methods generally assume the hazard functions are proportional among various risk groups. However, such an assumption may not be valid in genetic association studies, especially when complex interactions are involved. In addition, genetic association studies commonly adopt case-control designs.

11p vinarcissa 21-03-2023 5 1   Download

The CHRNA5/A3/B4 gene locus is associated with nicotine dependence and other smoking related disorders. While the non-synonymous CHRNA5 variant rs16969968 appears to be the main risk factor, linkage disequilibrium (LD) bins in the gene cluster carry frequent variants that regulate expression.

11p vitzuyu2711 29-09-2021 5 1   Download

Among adolescent novice smokers, craving is often the first, and is the most reported, symptom of nicotine dependence. Until now, little has been known about the development of craving symptoms in novice smokers.

12p vimontana2711 05-04-2021 9 2   Download

Recent research shows that nicotine dependence conveys additional health risks above and beyond smoking behavior. The current study examines whether smoking within 5 min of waking, an indicator of nicotine dependence, is independently associated with asthma outcomes.

6p vimontana2711 05-04-2021 11 2   Download

Pancreatic cancer is frequently resistant to cancer therapeutics. Smoking and alcoholism are risk factors and pancreatic cancer patients often undergo nicotine replacement therapy (NRT) and treatment for alcohol dependence.

12p vilisa271 22-09-2020 14 2   Download

The bacterial nicotine-degrading enzyme NicA2 isolated from P. putida was studied to assess its potential use in the treatment of tobacco dependence.

14p vihamax2711 21-04-2020 11 1   Download

The American Academy of Pediatrics advocates that pediatricians should be involved in tobacco counseling and has developed guidelines for counseling. We present a prognostic tool for use by health care practitioners in both clinical and non-clinical settings, to identify adolescents at risk of becoming daily smokers.

8p virubber2711 21-03-2020 8 1   Download

(bq) “abc of smoking cessation” has contents: the problem of tobacco smoking, why people smoke, assessment of dependence and motivation to stop smoking, use of simple advice and behavioural support, nicotine replacement therapy, bupropion and other non-nicotine pharmacotherapies, cessation interventions in routine health care,… and other contents.

54p tieu_vu15 07-09-2018 28 2   Download

Intraperitoneal injection of choline (30–90 mgÆkg )1 ) produced a dose-dependent increase in serum insulin, glu-cose and choline levels in rats.The increase in serum insulin induced by choline (90 mgÆkg )1 ) was blocked by pretreat-mentwith themuscarinic acetylcholine receptor antagonists, atropine (2 mgÆkg )1 ), pirenzepine (2 mgÆkg )1 ) and 4-diphe-nylacetoxy-N-methylpiperidine (2 mgÆkg )1 ) or the gangli-onic nicotinic receptor antagonist, hexamethonium (15 mgÆkg )1 ).

9p tumor12 20-04-2013 43 2   Download

Psychiatric disorders represent a complex interaction between psychological, developmental, neurobiological, and genetic factors. This book focuses on the neurobiological elements of psychiatric conditions. In the last 30 years, much has been learned about the neuroanatomic, neurophysiological, neurochemical, and molecular elements that contribute to major psychiatric illnesses such as schizophrenia, drug dependence, anxiety disorders, major depression, bipolar disorder, and dementias.

281p hyperion75 18-01-2013 49 7   Download

This book highlights the needs and healthcare concerns of women in their mid life.Women in middle age are often overlooked by medical practitioners. From the end of childbearing to old age, approximately ages 40–65 years, their health needs are complex and changing. This is a time of challenge and opportunity, when the physician and woman working collaboratively can change her health and future. Mid-life healthcare is far more than hormones.

387p kimngan_1 09-11-2012 86 4   Download

Silent information regulator 2 (Sir2) proteins, or sirtuins, are protein deacetylases dependent on nicotine adenine dinucleotide (NAD) and are found in organisms ranging from bacteria to humans. In eukaryotes, sirtuins regulate transcriptional repression, recombination, the celldivision cycle, microtubule organization, and cellular responses to DNA-damaging agents. Sirtuins have also been implicated in regulating the molecular mechanisms of aging. The Sir2 catalytic domain,

0p thulanh21 15-11-2011 50 1   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài:" Epidemiology, radiology, and genetics of nicotine dependence in COPD...

11p toshiba11 20-10-2011 63 3   Download

The nonmedical use of drugs presents social problems with important pharmacological aspects. Social aspects Rewards for the individual Decriminalisation and legalisation Dependence Drugs and sport Tobacco Dependence Nicotine pharmacology Effects of chronic smoking Starting and stopping use Passive smoking Ethyl alcohol Pharmacology Car driving and alcohol Chronic consumption Withdrawal Pregnancy Pharmacological deterrence Psychodysleptics • Experiences with psychodysleptics • Individual substances, especially cannabis Stimulants • cocaine, • amfetamines.

19p bigbaby87 03-09-2010 125 18   Download

Introduction: Nicotine is a main water-soluble alkaloid being contained in the tobacco plant (Nicotiana tabacum), which acts as an inducing compound for smoking-dependence. Twelve kinds of nicotine metabolites are known in rats [1]. Among them, cotinine is the major metabolite of nicotine; the half-life (T1/2) of cotinine is much longer (10–20 h) than that of nicotine (24–84 min). The qualitative analysis of cotinine in urine and saliva is being thus carried out as indicators for smoking during its abstinence therapy and for confirming passive smoking.

10p bigbaby87 01-09-2010 66 10   Download