![](images/graphics/blank.gif)
Non coding rnas
-
Prostate cancer (PCa) is one of the major tumor diseases that threaten men’s health globally, and biochemical recurrence significantly impacts its prognosis. Disulfidptosis, a recently discovered cell death mechanism triggered by intracellular disulfide accumulation leading to membrane rupture, is a new area of research in the context of PCa. Currently, its impact on PCa remains largely unexplored.
12p
vishanshan
27-06-2024
3
1
Download
-
Cyclin B2 (CCNB2), a member of the cyclin family, is an oncogene in multiple cancers, including nasopharyngeal carcinoma (NPC). However, the epigenetics mechanism for CCNB2 overexpression in NPC remains unclear. This study dissects the regulatory role of CCNB2 in NPC and the molecular mechanism.
14p
vishanshan
27-06-2024
2
1
Download
-
Long non-coding RNA (lncRNA) H19 has gained significant recognition as a pivotal contributor to the initiation and advancement of gynecologic cancers, encompassing ovarian, endometrial, cervical, and breast cancers. H19 exhibits a complex array of mechanisms, demonstrating dualistic effects on tumorigenesis as it can function as both an oncogene and a tumor suppressor, contingent upon the specific context and type of cancer being investigated.
14p
vishanshan
27-06-2024
1
1
Download
-
Emerging evidence suggests the dysregulation of long non-coding RNAs (lncRNAs) involved in pancreatic cancer (PC). However, the function of LINC00930 in PC has not been elaborated. In this study, we found that LINC00930 was significantly down-regulated in PC cell lines and tissues, and associated with tumor size, lymphatic metastasis, TNM stage and poor prognosis.
14p
vishanshan
27-06-2024
1
1
Download
-
Pancreatic adenocarcinoma (PDAC) ranks as the fourth leading cause for cancer-related deaths worldwide. N6-methyladenosine (m6A) and long non-coding RNAs (lncRNAs) are closely related with poor prognosis and immunotherapeutic effect in PDAC. The aim of this study is to construct and validate a m6A-related lncRNAs signature and assess immunotherapeutic drug sensitivity in PDAC.
15p
vikoch
27-06-2024
1
1
Download
-
Ebook "Molecular biology of long non-coding RNAs" will consolidate these ideas and models to better examine the most important issues in lncRNA biology. This will include critical studies that have led to the discovery and annotation of lncRNAs in numerous species, and the molecular mechanisms for a few lncRNA that have begun to emerge.
232p
tracanhphuonghoa1007
22-04-2024
1
1
Download
-
Ebook "The long and short noncoding RNAs in cancer biology" conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance).
455p
tracanhphuonghoa1007
22-04-2024
4
2
Download
-
Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified several molecular subtypes with distinct biological and clinicopathological characteristics. While MIBC subtyping has primarily been based on messenger RNA (mRNA), long non-coding RNAs (lncRNAs) may provide additional resolution.
13p
vibransone
28-03-2024
3
2
Download
-
IL-4-driven alternative macrophage activation and proliferation are characteristic features of both antihelminthic immune responses and wound healing in contrast to classical macrophage activation, which primarily occurs during inflammatory responses.
22p
vioraclene
31-03-2024
3
2
Download
-
Bài viết trình bày xây dựng đường chuẩn để định lượng nồng độ lncRNA IFI6lnc2 và EPB41L4A-AS1 bằng phương pháp real-time PCR. Phương pháp nghiên cứu: Sử dụng phương pháp real-time PCR định lượng tuyệt đối để xây dựng đường chuẩn dựa trên các mẫu chuẩn có nguồn gốc từ các plasmid tái tổ hợp chứa gen mã hóa cho lncRNA IFI6lnc2 và EPB41L4A-AS1.
11p
vicwell
06-03-2024
5
2
Download
-
The respiratory pathogen Streptococcus pneumoniae (the pneumococcus) is a genetically diverse bacterium associated with over 101 immunologically distinct polysaccharide capsules (serotypes).
23p
vicwell
29-02-2024
1
1
Download
-
Ebook "Untranslated gene regions and other non-coding elements: Regulation of eukaryotic gene expression" pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
63p
manmanthanhla0201
26-02-2024
5
1
Download
-
Part 1 book "Animal models and human reproduction" includes content: Anatomy of the reproductive system; anatomy of mammalian (endocrine) glands controlling the reproduction; models for investigating placental biology; early developmental programming of the ovarian reserve; ovarian function, and fertility; small non coding RNAS in gametogenesis; the ovarian follicle of cows as a model for human,... and other contents.
248p
muasambanhan04
07-01-2024
3
2
Download
-
A deep understanding of potential molecular biomarkers and therapeutic targets related to the progression of colorectal cancer (CRC) from early stages to metastasis remain mostly undone. Moreover, the regulation and crosstalk among diferent cancer-driving molecules including messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs) and micro-RNAs (miRNAs) in the transition from stage I to stage IV remain to be clarified, which is the aim of this study
22p
vimichaelfaraday
28-12-2023
5
4
Download
-
Neuroendocrine differentiation (NED) in colorectal cancer (CRC) cells has been known for decades, and our previous meta-analysis indicated that CRC patients with neuroendocrine differentiation have a lower 5-year survival rate. In recent years, an increasing number of studies have found that exosome-derived long non-coding RNAs (lncRNAs) play important roles in cancer progression and metastasis.
17p
vimichaelfaraday
28-12-2023
11
3
Download
-
Ebook "Bioinformatics in microRNA research" provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases.
283p
lucchinguyen
28-12-2023
6
2
Download
-
Ebook "MicroRNA protocols (Third edition)" focuses on the analysis of miRNA and its many components such as targets and expression profiling, regulation of gene expression, miRNA detection in biofluids, and its application in cancer and wound healing. The chapters in this book explore topics that’s cover biogenesis, isolation and profiling of miRNA, exosomal miRNAs, and the study of the functional significance of miRNAs.
314p
lucchinguyen
28-12-2023
5
2
Download
-
Ebook "Regulatory RNAs: Basics, methods and applications" is intended for readers with research or teaching interests in ncRNA biology and will provide a major information resource on current research in the fast-moving fields of RNA and gene expression regulation. Cutting-edge and concise, “Regulatory RNAs: Basics, Methods and Applications” promises to support vital research in the field of regulatory RNAs, ever-continuing to grow rapidly and gain increasing importance in basic and translational biology.
549p
lucchinguyen
28-12-2023
8
2
Download
-
N7-Methylguanosine (m7G) and long non-coding RNAs (lncRNAs) have been widely studied in cancer and have been found to be useful for assessing tumor progression. However, the role of m7G-related lncRNAs in lung squamous cell carcinoma (LUSC) remains unclear
17p
vileonardodavinci
23-12-2023
5
3
Download
-
Clear cell renal cell carcinoma is a common malignant tumor of the urinary system. The mechanism of its occurrence and development is unknown, and there is currently few effective comprehensive predictive markers for prognosis and treatment response.
16p
vileonardodavinci
23-12-2023
2
2
Download
CHỦ ĐỀ BẠN MUỐN TÌM
![](images/graphics/blank.gif)