Nosocomial pneumonia
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Klebsiella pneumoniae (Kp) Gram-negative bacteria cause nosocomial infections and rapidly acquire antimicrobial resistance (AMR), which makes it a global threat to human health. It also has a comparatively rare hypervirulent phenotype that can lead to severe disease in otherwise healthy individuals.
12p vicwell 29-02-2024 4 1 Download
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In this paper, we present a case of enterocolitis caused by MRSA following antibiotic treatment for a patient with necrotizing multilobar pneumonia and 60% total burn surface area (TBSA).
5p viintuit 26-09-2023 4 0 Download
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Aspiration of subglottic secretions past the endotracheal tube (ETT) cuff is a prerequisite for developing ventilator-associated pneumonia (VAP). Subglottic secretion drainage (SSD) ETTs reduce aspiration of subglottic secretions and have demonstrated lower VAP rates.
9p viottohahn 30-03-2022 11 1 Download
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Endotracheal tube (ETT) designs to decrease the risk of ventilator associated pneumonia (VAP) include supraglottic suctioning, and/or modifications of the cuff shape. The TaperGuard™ ETT has a tapered, polyvinylchloride cuff designed to reduce microaspiration around channels that form with a standard barrel-shaped cuff.
8p vizhangzhidong 29-12-2021 5 0 Download
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This finding was further confirmed genotypically by polymerase chain reaction that showed the presence of efflux genes AcrA, AcrB, TolC and mdtk in these isolates. The ability of metformin to inhibit efflux activity was compared with the reference efflux pump inhibitors verapamil and ascorbic acid. Metformin was more active than ascorbic acid and less active than verapamil. Up to our knowledge, this is the first report that shows that metformin has an efflux pump-inhibiting activity in Klebsiella pneumoniae.
8p mudbound 10-12-2021 9 1 Download
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Bài giảng Vai trò của Linezolid trong điều trị MRSA giúp bạn hiểu được định nghĩa về MRSA, cấu trúc và cơ chế tác đông của linezolid, vai trò linezolid trong điều trị MRSA,... Mời các bạn cùng tham khảo!
31p gongyuefei 10-08-2021 16 1 Download
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Pseudomonas aeruginosa (PA) is an opportunistic Gram-negative bacterium that causes serious life threatening and nosocomial infections including pneumonia. PA has the ability to alter host genome to facilitate its invasion, thus increasing the virulence of the organism. Sphingosine-1- phosphate (S1P), a bioactive lipid, is known to play a key role in facilitating infection.
19p viansan2711 30-07-2021 11 1 Download
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Hospital-acquired infection (HAI) is a growing problem all around the world particularly for countries with aging and high-density population such as Vietnam. In this review, we summarized the current status of HAIs in Vietnam regarding types of infection, rates of infection, hospital-stay duration and cost of treatment, and provided an overview with suggestions on strategies in combating these infections especially in Vietnamese settings. From quite dispersed and varied data reported in English and Vietnamese, we have seen HAI rates of less than 10%.
10p nguyenmyhuyen90 04-03-2021 13 1 Download
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Microbiological infection plays vital role in determining the outcome as well as cost and duration of the hospital stay for patients admitted in ICU setup. Of late nosocomial infections especially ventilator associated pneumonias (VAP) have been recognized to be associated with significant morbidity and mortality in intubated patients. It is of critical importance to do regular surveillance of important pathogen (like Methicillin resistant staphylococcus aureus (MRSA), extended spectrum beta lactamase (ESBL) and carbapenemase producers) and its resistance pattern.
12p kethamoi6 29-06-2020 21 2 Download
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Non fermenting Gram Negative Bacilli (NFGNB) once considered as contaminants, now emerged as a major cause of life threatening nosocomial infections and as multidrug resistant pathogens. Acinetobacter species are the opportunistic pathogens with increasing prevalance in the nosocomial infections. Community acquired infections are also common in Acinetobacter. It accounts for 10% of all community-acquired bacteremic pneumonias. To isolate, identify and detect Carbapenem resistance producing Acinetobacter spp., and confirm Metallo Beta Lactamase ( MBL) production by phenotypic methods.
10p trinhthamhodang5 16-05-2020 15 1 Download
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Ventilator Associated Pneumonia (VAP) is the most common intensive care unit (ICU) acquired nosocomial infection and it is considered as the second most common hospital acquired infection associated with higher mortality and morbidity. The aim of this study was to determine the microbial profile of pathogens causing VAP and their antibiotic susceptibility patterns over a period of five years in the intensive care unit (ICU) of a tertiary care hospital.
10p angicungduoc4 26-04-2020 13 1 Download
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Nosocomial infections are a critical issue among intubated patients. Respiratory tract infection in relation to intubation and/ or mechanical ventilation has been reported to vary from 4% to 28% and this rate has been thought to be 21 times higher than in patients without endotracheal tube. The aim of our study was to identify the pathogens isolated from culture of endotracheal tube aspirates and determine their antibiogram. Patients on mechanical ventilation (MV) for >48 h in the intensive care units (ICU), critical care unit (CCU), PICU and NICU were included in this study.
9p nguathienthan4 18-04-2020 11 0 Download
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Ventilator-associated pneumonia is defined as nosocomial pneumonia occurring more than 48 hours after patients have received mechanical ventilation. VAP in a critically ill patient significantly increases risk of mortality, ventilator time, length of stay and cost of care. The Endotracheal tube is a favourable site for biofilm formation. They are adherent cells which are embedded within a self-produced matrix of This EPS matrix impedes the normal functions of antibodies and the phagocytic cells of the immune system and leads to increased resistance to antibiotics.
8p cothumenhmong4 25-03-2020 8 0 Download
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Tigecycline, with broad in vitro antibacterial activity, has been widely used off-label for nosocomial pneumonia caused by multi-drug resistant Acinetobacter baumannii (MDRAB). However, many concerns have been raised about the efficacy of tigecycline treatment as the inconsistent results from previous clinical studies.
8p vimax2711 27-03-2020 9 1 Download
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Ventilator Associated Pneumonia (VAP) is defined as pneumonia that occurs 48 hours or more after endotracheal intubation or tracheostomy, caused by infectious agents not present or incubating at the time mechanical ventilation started. While critically ill patients experience a life-threatening illness, they commonly contract ventilator-associated pneumonia. This nosocomial infection increases morbidity and likely mortality as well as the cost of health care.
13p chauchaungayxua4 18-03-2020 11 0 Download
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Ventilator associated pneumonia is the second most common nosocomial infection in the intensive care unit (ICU) and the most common in mechanically ventilated patients. The present study was undertaken to elucidate the bacteriological profile causing VAP in our institution and finding its incidence by recent NHSN guidelines. Study was conducted for 1 year study period (June 2017- May 2018).
10p caygaocaolon2 14-03-2020 29 1 Download
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Extended spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-Kp) infection can cause significant morbidity and mortality in neonates. We investigated a nosocomial ESBL-Kp outbreak in a neonatal intensive care unit (NICU) of the University Hospital of Larissa (UHL), Central Greece.
8p vinatri2711 29-02-2020 13 1 Download
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Ventilator associated Pneumonia (VAP) is the second most common nosocomial infection in hospitals. Timely diagnosis and appropriate treatment will greatly decrease the mortality and morbidity.
9p trinhthamhodang3 12-02-2020 14 2 Download
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Studies throughout the world document that the nosocomial infections are a major cause of morbidity and mortality. Many factors contribute to the frequency of nosocomial infections like immunocompromised state of patients, invasive examinations and treatments, patient care practices and hospital environment which facilitate transmission of microbes among patients. Treatment is becoming difficult due to inappropriate use of antibiotics and hence resistance develops. Knowledge on antibiotic resistance pattern is essential for appropriate therapy.
7p nguaconbaynhay3 07-02-2020 50 3 Download
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Neonatal septicemia either acquired from the mother (vertical transmission) or nosocomial (horizontal transmission) is a forbidable problem encountered in the neonatal unit and is the commonest primary cause of morbidity and mortality among neonates. The present study was conducted in Department of Microbiology, Dr B R Ambedkar Medical College, Bengaluru, over a period of one year from June 2016 – May 2017. Blood sample were collected from 100 clinically suspected cases of neonatal septicemia admitted in the neonatal intensive care unit.
4p quenchua2 16-12-2019 14 0 Download