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Novel risk factors

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  • as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters.

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  • The chapter provides insight into the early assessment process and the application of precaution, an often poorly described management action rarely captured in peer review literature. The situation surrounding this potential new threat to blood safety was largely resolved in mid-2011 when it was determined that the virus was an artifact from contaminated patient samples and from contamination stemming from a diagnostic test kit widely used by researchers.

    pdf152p wqwqwqwqwq 20-07-2012 57 9   Download

  • In 1856, Rudolf Virchow published “Cellular pathology” based on macroscopic and microscopic observation of diseases, and described a triad of factors on thrombosis. The three components were vascular change, blood flow alteration, and abnormalities of blood constituents. Although Virchow originally referred to venous thrombosis, the theory can also be applied to arterial thrombosis, and it is considered that atherothrombus formation is regulated by the thrombogenicity of exposed plaque contents, local hemorheology, and blood factors.

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  • Ischemic heart disease continues to be the leading cause of morbidity and mortality in both developed and developing countries, and remains one of the most important public health problems. The continuous rise in the prevalence of disorders such as obesity, diabetes, dyslipidemia and hypertension is driving the ever-increasing number of incidences of ischemic heart disease.

    pdf462p wqwqwqwqwq 23-07-2012 37 7   Download

  • The following pages are devoted to a statistical analysis of the principal factors affecting credit risk. The information on which the study is based was obtained from a sample of 2,765 applications of persons to whom loans were granted. The data, secured through the cooperation of 21 large banks operating personal loan departments in 16 cities situated in ii states,1 are presented in a series of tables giving the distri- butions of good and of bad loans according to the several risk factors selected.

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  • While various glomerular disorders account for the most cases of end stage renal failure, the etio-pathogenesis of these conditions intrigued many investigators for decades. A clear knowledge of the etiology and pathogenesis is crucial for developing novel strategies to prevent and to treat these disorders. Notwithstanding the continuous emergence of new discoveries, we still have a long way to get any closer to a thorough understanding of the mechanisms of glomerular injury.

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  • It is important that cord blood transplantation is one of the risk factors of symptomatic adenoviremia (Robin et al., 2007), which develops to acute renal failure in the terminal stage (Abe T et al., 2009). At present, there is no established consensus about the treatment for acute renal failure induced by adenovirus after stem cell transplantation. This chapter focuses on the recent advances in diagnosis, mostly due to the development of molecular methods, and therapeutic interventions.

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  • The first risk factor is the traditional CAPM beta. The second factor is the difference in returns between high market-to-book companies and firms with low ratios of market value to book value. The third variable measures the difference in returns of small firms (S) minus big firms (B). The data series used were compiled by Fama and French. The Fama-French three factor model has been successfully applied not only in the United States but in Europe as well. The ability of the model to explain the cross-section of European stock returns has been documented by...

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  • But having more than one risk factor is especially serious, because risk factors tend to “gang up” and worsen each other’s effects. Having two risk factors increases the chance of developing heart disease fourfold. Having three or more risk factors increases the chance more than tenfold. The fact is, most women in midlife already have heart disease risk factors. Thirty-three percent of women ages 40 to 60 have one risk factor for heart disease that they can change.

    pdf102p quygia123 06-11-2012 28 0   Download

  • We build a three-factor term-structure of interest rates model and use it to price corporate bonds. The first two factors allow the risk-free term structure to shift and tilt. The third factor generates a stochastic credit-risk premium. To implement the model, we apply the Peterson and Stapleton (2002) diffusion approximation methodology. The method approximates a correlated and lagged-dependent lognormal diffusion processes. We then price options on credit-sensitive bonds.

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  • Rapidly expand access to diversified HIV testing and counselling services. HIV testing must be voluntary, confidential and accompanied by appropriate counselling, whether initiated by the client or the provider. Accelerated uptake of rights-based testing and counselling services for adults and children is required for prevention and early diagnosis and referral (as required) to care and treatment programmes and to support safe disclosure of HIV status.

    pdf229p nhamnhiqa 01-03-2013 19 1   Download

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