Nucleic acid structure

Ebook "Modified nucleic acids" spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs.

280p ladongphongthanh1008 22-04-2024 3 1   Download

Part 1 book "Molecular diagnostics - Fundamentals, methods, and clinical applications" includes content: Nucleic acids and proteins; gene expression and epigenetics; nucleic acid extraction methods; resolution and detection of nucleic acids; analysis and characterization of nucleic acids and proteins; nucleic acid amplifi cation; chromosomal structure and chromosomal mutations, gene mutations; DNA sequencing.

280p muasambanhan10 06-04-2024 2 0   Download

Part 2 book "Pharmaceutical design and development" includes content: Rational design of drugs based on molecular structure, nucleic acid therapies, transgenic animal models, diagnostic applications of biotechnology, future prospects.

104p muasambanhan10 03-04-2024 3 2   Download

Ebook "Quadruplex nucleic acids (Topics in Current chemistry, Volume 330)" includes descriptions of two physical chemical approaches that provide mechanistic details of quadruplex reactions. Kinetic studies that unravel the mechanism of tetramolecular quadruplex assembly are presented by the team from the Mergny laboratory, studies that may be most relevant for the nanotechnology community.

285p coduathanh1122 27-03-2024 2 1   Download

Ebook "Extracellular nucleic acids (Nucleic acids and molecular biology, Volume 25)" covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them. Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences.

239p cotieubac1004 15-03-2024 0 0   Download

Ebook "Nucleic acids in the gas phase" gives physical chemists a broader view of potential biological applications of their techniques for the study of nucleic acids in the gas phase. It provides organic chemists, biophysicists, and pharmacologists with an introduction to new techniques they can use to find the answers to yet unsolved questions. Laboratory sciences have bloomed with a variety of techniques to decipher the properties of the molecules of life.

297p nhanphanguyet 28-01-2024 6 2   Download

Ebook "Mass spectrometry: Developmental approaches to answer biological questions" is structured as follows: after a brief introduction of the usual and most popular applications for mass spectrometry in proteomics, the most recent research and developments in mass spectrometry-based methodologies will be explored. As of now, several investigations tried to improve the quantification of proteins by mass spectrometry, the determination of post-translational modifications, the protein-protein and protein-nucleic acids interaction or the proteins structures.

77p nhanphanguyet 28-01-2024 6 2   Download

Ebook "NMR in biological systems: From molecules to humans" caters to the needs of: (i) graduate students who mostly learn such techniques from senior post-docs in the laboratory; (ii) those who are not experts in NMR but wish to understand if a particular problem in animal, plant, medical and pharmaceutical sciences can be answered by NMR; and (iii) those who are experts in chemistry and biochemistry and wish to know how NMR can provide them information on structural or functional aspect of proteins, nucleic acids, cells and tissues, human and plant organs and other biological materials.

552p tachieuhoa 28-01-2024 8 2   Download

Part 1 book "Biochemistry for dummies" includes content: Biochemistry - What you need to know and why; seems so basic - water chemistry and Ph, fun with carbon - organic chemistry; amino acids - the building blocks of protein; protein structure and function enzyme kinetics - getting there faster, what we crave - carbohydrates; lipids and membranes, nucleic acids and the code of life.

170p oursky05 20-09-2023 6 3   Download

Part 1 book "Fundamentals of biochemistry, life at the molecular level" includes content: Introduction to the chemistry of life, water, nucleotides, nucleic acids and genetic information amino acids, proteins - primary structure lipids and biological membranes, membrane transport, enzymatic catalysis,... and other contents.

380p oursky05 20-09-2023 6 2   Download

Part 2 book "Fundamentals of biochemistry, life at the molecular level" includes content: Nucleotide metabolism, nucleic acid structure, DNA replication, repair, and recombination 26 transcription and RNA processing, protein synthesis, regulation of gene expression.

358p oursky05 20-09-2023 4 2   Download

Ebook Principles of biochemistry (8th edition): Part 1 includes content: The foundations of biochemistry; water, the solvent of life; amino acids, peptides, and proteins; the three dimensional structure of proteins protein function enzymes carbohydrates and glycobiology; nucleotides and nucleic acids; DNA-Based information technologies.

1283p oursky05 20-09-2023 2 2   Download

Part 1 of ebook "Lehninger principles of biochemistry (7th edition)" provides readers with contents including: the foundations of biochemistry; amino acids, peptides, and proteins; the three-dimensional structure of proteins; protein function; carbohydrates and glycobiology; nucleotides and nucleic acids; DNA-based information technologies;...

1486p lytamnguyet 04-08-2023 8 4   Download

Part 1 of ebook "Principles of biochemistry (4th edition)" provide readers with content about: the foundations of biochemistry; structure and catalysis; water; amino acids, peptides, and proteins; the three-dimensional structure of proteins; protein function; enzymes; carbohydrates and glycobiology; nucleotides and nucleic acids; DNA-based information technologies; lipids; biological membranes and transport; biosignaling; bioenergetics and metabolism; principles of bioenergetics;...

526p hanlinhchi 11-11-2022 12 3   Download

G-Quadruplexes, a class of noncanonical but highly stable nucleic acid structures, have the potential to be part of the regulatory mechanism of cells. They can form in the genome where the double-stranded helix is unwound to facilitate formation of a G-quadruplex. The biological significance of these structures is yet to be understood entirely. This work presents a novel approach and investigates common characteristics in the distribution of G-quadruplexes relative to genes in plants through analysis of genomes and gene expressions.

16p tudichquannguyet 29-11-2021 6 1   Download

High hydrostatic pressure and low temperatures make the deep sea a harsh environment for life forms. Actin organization and microtubules assembly, which are essential for intracellular transport and cell motility, can be disrupted by high hydrostatic pressure. High hydrostatic pressure can also damage DNA. Nucleic acids exposed to low temperatures can form secondary structures that hinder genetic information processing.

9p vibeauty 23-10-2021 15 1   Download

Chapter 5 - The structure and function of macromolecules. After reading this chapter and attending lecture, the student should be able to: List the four major classes of biomolecules, explain how organic polymers contribute to biological diversity, describe how covalent linkages are formed and broken in organic polymers,...

86p tradaviahe19 29-03-2021 10 1   Download

The temperature downshift results in (1) decrease in membrane fluidity (2) changes in nucleic acid structures (3) reduced ribosome function (4) inefficient protein folding. Bacteria respond to this low temperature change by producing cold-shock proteins (CSPs) that bind to single-stranded RNA and DNA thereby, maintaining cell physiology. CSPs have been widely studied in Escherichia coli and Bacillus subtilis. Here we discuss the cold adaptation by desaturase system, RNA chaperone, and transcription antitermination function of CspA homologues.

8p cothumenhmong9 18-01-2021 15 2   Download

The structures of biological macromolecules provide a framework for studying their biological functions. Three-dimensional structures of proteins, nucleic acids, or their complexes, are difficult to visualize in detail on flat surfaces, and algorithms for their spatial superposition and comparison are computationally costly.

11p viwyoming2711 16-12-2020 18 1   Download

The PCR technique and its variations have been increasingly used in the clinical laboratory and recent advances in this field generated new higher resolution techniques based on nucleic acid denaturation dynamics.

14p vikentucky2711 26-11-2020 3 1   Download