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Oxygen homeostasis
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Ebook "Mitochondria and cell death" examines the role of mitochondria in different types of cell death, including apoptotic and necrotic cell deaths. Topics discussed include mitochondrial outer membrane permeabilization (MOMP) and the permeability transition pore; core processes such as calcium handling, fission and fusion, reactive oxygen species generation, and maintenance of mitochondrial DNA fidelity and protein folding homeostasis; and retrograde signaling between mitochondria and other cellular components, including the important role of mitochondria in antiviral immunity.
242p
tracanhphuonghoa1007
22-04-2024
2
2
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Precursor B-cell acute lymphoblastic leukemia (pre-B ALL) is the most common hematological malignancy in children. Cellular metabolic reorganization is closely related to the progression and treatment of leukemia.
16p
vischultz
20-10-2023
4
1
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(BQ) Ebook Studies on renal disorders: Part 2 presents the following content: Involvement of hypoxia-inducible factor 1 in physiological and pathological responses to continuous and intermittent hypoxia: role of reactive oxygen species; regulation of oxygen homeostasis by prolyl hydroxylase domains; oxygen-dependent regulation of erythropoiesis; intricate link between hypoxia and oxidative stress in chronic kidney disease; RNA interference and the regulation of renal gene expression in hypoxia;...
377p
runordie7
30-08-2022
8
2
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The study was aimed to determine the measurement accuracy of The CDI™ blood parameter monitoring system 500 (Terumo Cardiovascular Systems Corporation, Ann Arbor MI) in the real-time continuous measurement of arterial blood gases under different cardiocirculatory stress conditions.
9p
viisaacnewton
26-04-2022
10
1
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Autophagy and DNA repair are two essential biological mechanisms that maintain cellular homeostasis. Impairment of these mechanisms was associated with several pathologies such as premature aging, neurodegenerative diseases, and cancer. Intrinsic or extrinsic stress stimuli (e.g., reactive oxygen species or ionizing radiation) cause DNA damage. As a biological stress response, autophagy is activated following insults that threaten DNA integrity.
18p
thiencuuchu
27-11-2021
8
1
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Carotid body O2-chemosensitivity determines the hypoxic ventilatory response (HVR) as part of crucial regulatory reflex within oxygen homeostasis. Nicotine has been suggested to attenuate HVR in neonates of smoking mothers.
8p
vimaine2711
26-03-2021
5
1
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HIF-1 (hypoxia-inducible factor 1) is a transcriptional activator that functions as a critical regulator of oxygen homeostasis. Recently, a large number of epidemiological studies have investigated the relationship between HIF-1α C1772T/G1790A polymorphisms and cancer susceptibility. However, the results remain inconclusive.
16p
vialabama2711
21-09-2020
6
0
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Cancer cells modify the balance between fatty acid (FA) synthesis and uptake under metabolic stress, induced by oxygen/nutrient deprivation. These modifications were shown to alter the levels of individual triglyceride (TG) or phospholipid sub-species.
11p
vikuala271
13-06-2020
13
1
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Salinity tolerance is a physiologically multi-faceted trait attributed to multiple mechanisms. Three barley (Hordeum vulgare) varieties contrasting in their salinity tolerance were used to assess the relative contribution of ionic, osmotic and oxidative stress components towards overall salinity stress tolerance in this species, both at the whole-plant and cellular levels.
13p
viminato2711
22-05-2020
12
1
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Oxidative stress results from an imbalance between the production of reactive oxygen species and the antioxidants defences, in favour of the former. In recent years, the association between oxidative processes, environmental change and life histories has received much attention. Metals are important inducers of oxidative stress in aquatic organisms, promoting formation of reactive oxygen species through two mechanisms.
15p
trinhthamhodang3
12-02-2020
19
1
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Antioxidant effects of twelve 3-substituted-5,5 diphenylhydantoins in concentrations of 0.01, 0.1, 1, 10, and 100 µM on human colon cancer cell line HCT-116 were determined 24 h after treatment. The concentrations of superoxide anion radical (O2.-), nitrites (NO2-), and total glutathione were determined spectrophotometrically.
7p
sony2711
01-02-2019
17
1
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To sustain life mammals have an absolute and continual requirement for oxygen, which is necessary to produce energy for normal cell survival and growth. Hence, main-tainingoxygen homeostasis is a critical requirement and mammals have evolved a wide range of cellular and phy-siological responses to adapt to changes in oxygen avail-ability. In the past few years it has become evident that the transcriptional protein complex hypoxia-inducible factor (HIF) is a key regulator of these processes.
10p
tumor12
20-04-2013
27
2
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Three pairs of parental (q + ) and established mitochondrial DNAdepleted (q 0 ) cells, derived frombone, lungandmuscle were used to verify the influence of the nuclear background and the lack of efficient mitochondrial respiratory chain on antioxidant defences and homeostasis of intracellular reactive oxygen species (ROS).
11p
awards
05-04-2013
40
2
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Intracellular heme concentrations are maintained in part by heme degrada-tion, which is catalyzed by heme oxygenase. Heme oxygenase consists of two structurally related isozymes, HO-1 and HO-2. Recent studies have identified HO-2 as a potential oxygen sensor. To gain further insights into the regulatory role of HO-2 in heme homeostasis, we analyzed the expres-sion profiles of HO-2 and the biochemical consequences of HO-2 knock-down with specific short interfering RNA (siRNA) in human cells.
14p
inspiron33
23-03-2013
29
2
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White and Gibson Journal of Orthopaedic Surgery and Research 2010, 5:27 http://www.josr-online.com/content/5/1/27 RESEARCH ARTICLE Research article Open Access The effect of oxygen tension on calcium homeostasis in bovine articular chondrocytes Rachel White and John S Gibson* Abstract Background: Articular chondrocytes normally experience a lower O2 tension compared to that seen by many other tissues. This level may fall further in joint disease. Ionic homeostasis is essential for chondrocyte function but, at least in the case of H+ ions, it is sensitive to changes in O2 levels.
7p
sting01
15-01-2012
37
4
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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : The effect of oxygen tension on calcium homeostasis in bovine articular chondrocytes
7p
panasonic10
14-01-2012
37
3
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