Pharmaceutical applications

Astaxanthin (AST) and pycnogenol (PYC) are natural bioactive compounds commonly used in pharmaceuticals and functional foods due to their highly antioxidant activity and potential health benefits. However, the widespread application of astaxanthin is hindered by its poor water solubility and highly unsaturated structure. In this study, nanoparticles co-delivering astaxanthin and pycnogenol (NAP) were fabricated to enhance the dispersibility, stability, and bioavailability of astaxanthin.

9p vifilm 11-10-2024 1 0   Download

This paper presents the application of HKUST-1 as a catalyst for the reduction reaction to produce 4- aminophenol (4-AP) - a pharmaceutical precursor for the synthesis of paracetamol.

10p vikwong 29-09-2024 1 0   Download

Wastewater of Sao Thai Duong Pharmaceuticals & Cosmetics Factory contains high concentration (more than 1000 mg/l) COD and BOD. Besides, some persistent substances are also found such as surfactants, emulsion oil and ammonium.

10p vifilm 24-09-2024 1 1   Download

In order to explore the importance of the Antheroporum genus in pharmaceutical applications, two bioactivities of A. harmandii plant extracts have been evaluated in this study. Antimicrobial and antioxidant activities of A. harmandii extracts will provide evidences for further chemical composition studies to detect new bioactive compounds from this species.

9p dianmotminh02 03-05-2024 6 2   Download

Developed a chemometric-photometric analysis process in combination with Kalman filter method to simultaneously analyze mixtures of 2 and 3 substances with molecular absorption spectra overlapping in pharmaceutical samples; apply the process has been built to simultanneously analyze mixtures 2 and 3 substances in some pharmaceuticals are on the market Vietnam.

26p nguathienthan12 23-05-2021 23 3   Download

The experimental results show that the highest photocatalytic activity was obtained from the Ag (5) doped Zn-0.75Al-0.25La-CO3 photocatalysts calcined at 500 0C with a degradation efficiency of 99,4 after 40 min of irradiation only. This study could provide a new route for the fabrication of high performance photocatalysts and facilitate their application in the environmental remediation issues.

13p tamynhan4 06-09-2020 10 3   Download

Biotherapeutics (BTs), one of the fastest growing classes of drug molecules, offer several advantages over the traditional small molecule pharmaceuticals because of their relatively high specificity, low off-target effects, and biocompatible metabolism, in addition to legal and logistic advantages. However, their clinical utility is limited, among other things, by their high immunogenic potential and/or variable therapeutic efficacy in different patient populations.

7p caothientrangnguyen 09-05-2020 22 0   Download

Appreciate the diversity of biotechnology applications and the fundamentals of biotechnology, distinguish biotechnology from traditional appreciate the diversity of biotechnology applications and the fundamentals of biotechnology, distinguish biotechnology from distinguish biotechnology from traditional traditional pharmaceuticals, understand the value proposition of biotechnology companies,... As the main contents of the document "Functional overview of the biotechnology industry". Invite you to consult

36p thuyancn 21-10-2015 44 5   Download

This minireview is based on a lecture given at the First Maga Circe Confer-ence on metabolomics held at Sabaudia, Italy, in March 2006 in which the analytical and statistical techniques used in metabonomics, efforts at stan-dardization and some of the major applications to pharmaceutical research and development are reviewed.

12p galaxyss3 21-03-2013 29 2   Download

Systems biology has received an ever increasing interest during the last decade. A large amount of third-party funding is spent on this topic, which involves quantitative experimentation integrated with computational modeling. Industrial companies are also starting to use this approach more and more often, especially in pharmaceutical research and biotechnology.

91p cosis54 04-01-2013 46 5   Download

of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, 986025 Nebraska Medical Center, COP 3026, Omaha, NE 68198-6025, USA 2Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, 30 South 2000 East, Salt Lake City, UT 84112, USA 3Department of Radiology/Radiobiology Division, University of Utah, 729 Arapeen Dr., Salt Lake City, UT 84108, USA 4Washington University in St. Louis, 6515 Wydown Blvd., Campus Box 3519, St.

9p thulanh13 15-10-2011 37 1   Download

The most widely used analytical separation technique for the qualitative and quantitative determination of chemical mixtures in solution in the pharmaceutical industry is high-performance liquid chromatography (HPLC). However, conventional detectors used to monitor the separation, such as UV, refractive index, fluorescence, and radioactive detectors, provide limited information on the molecular structure of the components of the mixture. Mass spectrometry (MS) and nuclear magnetic resonance (NMR) are the primary analytical techniques that provide structural information on the analytes.

36p bigbaby87 03-09-2010 120 16   Download

For much of the early development of liquid chromatography, separations were carried out at ambient temperature and many laboratories did not attempt to regulate or control the temperature of the column. Frequently, the column would be mounted on the side of the pump or detector and thus would be subjected to changes in the room temperature or changes due to external factors, such as sunlight. However, the influence of temperature on the retention times of analytes was well known and had been studied by a number of groups—in particular, Melander et al. [1].

25p bigbaby87 03-09-2010 77 12   Download

Recent advances in mass spectrometry have rendered it an attractive and versatile tool in industrial and academic research laboratories. As a part of this rapid growth, a considerable body of literature has been devoted to the application of mass spectrometry in clinical studies. In concert with separation techniques such as liquid chromatography, mass spectrometry allows the rapid characterization and quantitative determination of a large array of molecules in complex mixtures.

36p bigbaby87 03-09-2010 114 12   Download

Over 25 years ago, Horvath and Melander, in their fundamental work [1], discussed the reason behind the explosive popularity of reversed-phase liquid chromatography (RPLC) for analytical separations. It was estimated that about 80–90% of all analytical separations were performed in RPLC mode, and the authors noted that “the variation of eluent composition alone extends both retention and selectivity in HPLC [high-performance liquid chromatography] over an extremely broad range.

34p bigbaby87 03-09-2010 127 40   Download