Pharmacological modulation
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Part 2 book "Rang and Dale's pharmacology" includes content: Respiratory system; the kidney, the gastrointestinal tract, the control of blood glucose and drug treatment of diabetes mellitus, obesity, the pituitary and the adrenal cortex, the thyroid, the reproductive system, bone metabolism, chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases,... and other contents.
442p dianmotminh03 03-06-2024 1 0 Download
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Part 1 book "Goodman and gilmans the pharmacological basis of therapeutics" includes content: General principles, neuropharmacology, modulation of pulmonary, renal, and cardiovascular function, inflammation, immunomodulation, and hematopoiesis
774p zizaybay1101 30-04-2024 2 2 Download
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Ebook "Breast cancer chemosensitivity" include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents.
187p tracanhphuonghoa1007 22-04-2024 3 1 Download
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Ebook "Small molecule therapeutics for schizophrenia" covers all relevant aspects of drug research, e.g.
327p tracanhphuonghoa1007 22-04-2024 3 3 Download
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Ebook "Chemokines: Chemokines and their receptors in drug discovery" covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level,...
248p tudohanhtau1006 29-03-2024 1 1 Download
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Identification of causal genes for polygenic human diseases has been extremely challenging, and our understanding of how physiological and pharmacological stimuli modulate genetic risk at disease-associated loci is limited.
16p viellison 28-03-2024 7 2 Download
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Part 2 book "Rang and Dale's pharmacology" includes content: Chemical transmission and drug action in the central nervous system, amino acid transmitters, other transmitters and modulators, neurodegenerative diseases, general anaesthetic agents, analgesic drugs, local anaesthetics and other drugs affecting sodium channels, anxiolytic and hypnotic drugs, antiepileptic drugs, antipsychotic drugs, antidepressant drugs, psychoactive drugs, drug abuse and dependence
348p muasambanhan05 22-01-2024 4 2 Download
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Part 1 book "Handbook of veterinary pharmacology" includes content: Principles of drug absorption, drug disposition, and drug action; principles of drug absorption, drug disposition, and drug action; autacoids and their pharmacological modulators autacoids and their pharmacological modulators, behavior modifying drugs, anesthetics, nonsteroidal anti inflammatory drugs, drugs acting on the cardiovascular system, diuretics.
234p oursky05 20-09-2023 10 2 Download
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In the present study, ethanolic extract of Mesua ferrea L. stamens was investigated for its potential to reverse some features of bronchial asthma in ovalbumin-induced murine model of asthma. Mesua ferrea commonly called nagakeshar (Family, Calophyllaceae) is a well-known antiallergic drug in the Asian folk system of medicines. In the present work, pharmacological studies are done to provide scientific evidence for therapeutic potential of plants in allergic asthma.
13p lyhuyenthu 31-01-2023 4 2 Download
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Chemoresistance of glioblastoma multiforme (GBM) has been attributed to the presence within the tumor of cancer stem cells (GSCs). The standard therapy for GBM consists of surgery followed by radiotherapy and the chemotherapeutic agent temozolomide (TMZ).
12p virose2711 25-09-2020 15 1 Download
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Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease virus (NDV) strain NDV/FMW virotherapy of drug-resistant lung cancer cells.
15p vilisa271 22-09-2020 22 0 Download
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Expression of the microRNA miR-21 has been found to be altered in almost all types of cancers and it has been classified as an oncogenic microRNA or oncomir. Due to the critical functions of its target proteins in various signaling pathways, miR-21 is an attractive target for genetic and pharmacological modulation in various cancers.
16p vinaypyidaw2711 26-08-2020 10 2 Download
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Living organisms are frequently exposed to more than one xenobiotic at a time either by ingestion of contaminated food/fodder or due to house-hold practices, occupational hazards or through environment.
17p viorochimaru2711 30-05-2020 11 1 Download
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Amphetamine and amphetamine derivatives are suggested to induce an immunosuppressive effect. However, knowledge of how amphetamines modulate intracellular signaling pathways in cells of the immune system is limited.
13p vienzym2711 03-04-2020 17 2 Download
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Protein-Protein Interactions (PPIs) are key for many cellular processes. The characterization of PPI interfaces and the prediction of putative ligand binding sites and hot spot residues are essential to design efficient small-molecule modulators of PPI.
11p vienzym2711 03-04-2020 11 1 Download
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Cytarabine is used in the treatment of acute myeloid leukemia (AML). Low-dose cytarabine can be combined with valproic acid and all-trans retinoic acid (ATRA) as AML-stabilizing treatment. We have investigated the possible risk of immunotoxicity by this combination.
16p vienzym2711 03-04-2020 20 1 Download
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Many anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility.
13p vienzym2711 03-04-2020 13 2 Download
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Central disinhibition is a mechanism involved in the physiopathology of fibromyalgia. Melatonin can improve sleep quality, pain and pain threshold.
14p vienzym2711 03-04-2020 11 3 Download
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Glucocorticoids affect peripheral immune responses, including modulation of T-cell activation, differentiation, and apoptosis. The quantity and quality of T-cell receptor (TCR)-triggered intracellular signals modulate T-cell function. Thus, glucocorticoids may affect T cells by interfering with the TCR signaling cascade.
12p vienzym2711 03-04-2020 12 2 Download
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GPR40 is a G-protein coupled receptor regulating free fatty acid induced and also glucose induced insulin secretion. We generated neonatally-streptozotocin-treated female rats (n-STZ) and treated them with CNX-011-67, a GPR40 agonist to examine the role of GPR40 in modulation of glucose metabolism, insulin secretion and content.
15p vienzym2711 03-04-2020 9 1 Download