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Pragmatic trial
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Violence in the healthcare workplace has been a global concern for over two decades, with a high prevalence of violence towards healthcare workers reported. Workplace violence has become a healthcare quality indicator and embedded in quality improvement initiatives of many healthcare organizations.
13p
vishanshan
27-06-2024
3
1
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Protocol of the Comparison of Intravesical Therapy and Surgery as Treatment Options (CISTO) study: A pragmatic, prospective multicenter observational cohort study of recurrent high-grade non-muscle invasive bladder cancer
12p
vileonardodavinci
23-12-2023
2
2
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Aromatase inhibitors (AI) are frequently used to treat hormone-receptor-positive breast cancer, but they have multiple adverse effects (e.g., osteoporosis, arthralgia), resulting in premature therapy discontinuation/ switch. Physical activity (PA) can attenuate these negative effects and improve quality of life (QoL).
17p
vioracle
29-09-2023
7
2
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Pragmatic (trial) informatics: A perspective from the NIH Health Care Systems Research Collaboratory
Pragmatic clinical trials (PCTs) are research investigations embedded in health care settings designed to increase the efficiency of research and its relevance to clinical practice. The Health Care Systems Research Collaboratory, initiated by the National Institutes of Health Common Fund in 2010, is a pioneering cooperative aimed at identifying and overcoming operational challenges to pragmatic research.
6p
visteverogers
24-06-2023
4
2
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Querying electronic health records (EHRs) to find patients meeting study criteria is an efficient method of identifying potential study participants. We aimed to measure the effectiveness of EHR-driven recruitment in the context of ADAPTABLE (Aspirin Dosing: A Patient-centric Trial Assessing Benefits and LongTerm Effectiveness)—a pragmatic trial aiming to recruit 15 000 patients.
6p
visteverogers
24-06-2023
5
2
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We identified challenges and solutions to using electronic health record (EHR) systems for the design and conduct of pragmatic research. We are hopeful our collection of specific EHR challenges and research needs will drive health system leaders, policymakers, and EHR designers to support these suggestions to improve our national capacity for generating real-world evidence.
15p
vighostrider
25-05-2023
4
2
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To examine whether the Wellness Incentive and Navigation (WIN) intervention can improve health-related quality of life (HRQOL) among Medicaid enrollees with co-occurring physical and behavioral health conditions.
10p
vigamora
25-05-2023
7
2
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This thesis contributes to a better understanding of the relationship between residential energy efficiency and health. The thesis argues that residential energy efficiency improvements are complex interventions in complex socio‐technical systems.
765p
runthenight04
02-02-2023
9
4
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Multimorbidity is a major problem in Europe, increasing the need for prevention and rehabilitation programs. In Germany no guidelines have been developed that focus on patients with multiple chronic non-communicable diseases (NCDs). Benefits of physical activity (PA) and exercise in NCDs have been proven, but most interventions focus on single conditions.
21p
viferrari
28-11-2022
8
2
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While effective physical activity referral schemes (PARSs) and related structures for promoting physical activity (PA) already exist in several countries, in Germany, PARSs have not yet been implemented systematically and nationwide. This study protocol aims to evaluate the developed PARS for people with non-communicable diseases (NCDs) in Germany regarding its potential effectiveness and implementation success.
11p
viferrari
28-11-2022
7
2
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Positron emission tomography targeting the prostate specific membrane antigen (PSMA PET/CT) has demonstrated unparalleled performance as a staging examination for prostate cancer resulting in substantial changes in management. However, the impact of altered management on patient outcomes is largely unknown.
11p
vikolindagrabar
27-07-2022
9
2
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Test ventilating prior to administration of neuromuscular blockade (NMB) in order to avoid a cannot intubate-cannot ventilate situation is a classic anesthesia teaching. The primary aim of our study was to show that facemask ventilation (FMV) after NMB was not inferior to FMV prior to NMB with respect to exhaled gas volumes before and after their administration.
9p
viisaacnewton
25-04-2022
10
1
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The healthcare system needs effective strategies to identify the most vulnerable group of older patients, assess their needs and plan their care proactively. To evaluate the effectiveness of comprehensive geriatric assessment (CGA) of older adults with a high risk of hospitalisation we conducted a prospective, pragmatic, matched-control multicentre trial at 19 primary care practices in Sweden.
9p
viisaacnewton
25-04-2022
11
4
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Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. We tested this hypothesis in a multi-center study.
10p
viottohahn
30-03-2022
4
1
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Chronic disease management models of care provide an opportunity to assist home care clients to manage their disease burden. However, pragmatic trial management practices and lessons learned from such models are poorly illustrated in the literature.
10p
vinobelprisen
26-03-2022
12
4
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Postoperative delirium is common in older adults, especially in those patients undergoing spine surgery, in whom it is estimated to occur in > 30% of patients. Although previously thought to be transient, it is now recognized that delirium is associated with both short- and long-term complications.
10p
vizhangzhidong
29-12-2021
10
0
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Counselling is considered to be a promising approach to increasing physical activity (PA) in people with chronic obstructive pulmonary disease (COPD). The aim of the current study was to investigate whether a PA counselling program for people with COPD, when embedded in a comprehensive outpatient pulmonary rehabilitation (PR) program, increased their daily PA.
12p
vimackenziebezos
29-11-2021
12
1
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Lumbosacral radicular syndrome (LRS) is a self-limiting, benign, painful and impairing condition caused by lumbar disc herniation and inflammatory processes around the nerve root. Segmental epidural steroid injections (SESIs) are helpful to reduce radicular pain on a short-term basis.
8p
viannito2711
20-04-2021
11
2
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Comprehensive rehabilitation, involving health professionals from various disciplines, is widely used as an adjunct to pharmacological and surgical treatment in people with rheumatic diseases. However, the evidence for the clinical- and cost-effectiveness of such interventions is limited, and the majority of those who receive rehabilitation are back to their initial health status six to 12 months after discharge.
13p
viannito2711
20-04-2021
21
2
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Ankle fractures account for 9% of all fractures with a quarter of these occurring in adults over 60 years. The short term disability and long-term consequences of this injury can be considerable.
9p
viannito2711
20-04-2021
19
2
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