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Protein velocity
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Ebook "Kinesin protocols (Methods in molecular biology, Volume 164)" present a wide range of domain organizations with a motor domain located at different positions in the molecule. Their motility properties are also variable in directionality, velocity, and such other characteristics as bundling activity and processivity. Finally, and most important, they practicipate in a multitude of cellular functions.
228p
manmanthanhla0201
26-02-2024
3
1
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Ebook "Analytical ultracentrifugation of polymers and nanoparticles" is divided into chapters concerning instrumentation, sedimentation velocity runs, density gradient runs, application examples and future developments. In particular, the detailed application chapter demonstrates the versatility and power of AUC by means of many interesting and important industrial examples. Thus the book concentrates on practical aspects rather than details of centrifugation theory.
249p
manmanthanhla0201
27-02-2024
4
2
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Emerging single-cell technologies profile multiple types of molecules within individual cells. A fundamental step in the analysis of the produced high-dimensional data is their visualization using dimensionality reduction techniques such as t-SNE and UMAP.
9p
viarchimedes
26-01-2022
16
0
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The simultaneous quantification of protein and RNA makes possible the inference of past, present, and future cell states from single experimental snapshots. To enable such temporal analysis from multimodal single-cell experiments, we introduce an extension of the RNA velocity method that leverages estimates of unprocessed transcript and protein abundances to extrapolate cell states.
6p
viarchimedes
26-01-2022
10
0
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Synonymous mutations do not change the protein sequences. Automatically, they have been regarded as neutral events and are ignored in the mutation-based cancer studies. However, synonymous mutations will change the codon optimality, resulting in altered translational velocity.
13p
vianrose2711
27-04-2021
9
2
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Overexpression the KCNJ3, a gene that encodes subunit 1 of G-protein activated inwardly rectifying K+ channel (GIRK1) in the primary tumor has been found to be associated with reduced survival times and increased lymph node metastasis in breast cancer patients
15p
vimale2711
25-08-2020
9
2
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Dispersal of glioblastoma (GBM) cells leads to recurrence and poor prognosis. Accordingly, molecular pathways involved in dispersal are potential therapeutic targets. The mitogen activated protein kinase/extracellular signal regulated kinase (MAPK/ERK) pathway is commonly dysregulated in GBM, and targeting this pathway with MEK inhibitors has proven effective in controlling tumor growth.
11p
vimale2711
21-08-2020
9
1
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Malnutrition is still public health problem in some parts of the world and causes irreversible damage at infant stage. Infants require high energy and nutrient dense foods because of their high growth velocity. Feeding fortified complementary blended foods is one of the options to treat malnourished infants. These foods are prepared with cereallegume blend, oil, sugar, vitamin/minerals and animal source protein. Complementary foods with high sugar content (> 15%) are not recommended to treat malnourished group. Animal source protein in complementary foods leads to hike in production cost.
8p
caygaocaolon5
27-05-2020
32
1
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Four different concentrations (10.0 ppm; 20.0 ppm; 40.0 ppm and 50.0 ppm) of the aqueous solution of seed powder of Syzigium cumini (L) concentrations was used to treat the leaves of mulberry and fed to the fifth instar larvae of bivoltine, crossbreed silkworm, Bombyx mori (L) Race: Bivoltine Cross Breed [(CSR6 x CSR26) x CSR2 x CSR27)] for first four days of fifth instar larvae. The larvae fed with untreated and water treated leaves were also maintained. The midgut enzyme (protease and amylase) bioassays were carried out on fifth day.
12p
nguaconbaynhay1
04-12-2019
15
1
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The present study examined the effects of 24-h and 72-h NaCl treatment on germination, germination velocity, and the associated biochemical changes in protein and RNA contents of 2 seed morphs, and compared these effects after transfer into distilled water or 10 mM thiourea solution.
9p
vitamix
15-02-2019
18
1
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A cDNA sequence fromSchizosaccharomyces pombewith similarity to 6,7-dimethyl-8-ribityllumazine synthase was expressed in a recombinant Escherichia colistrain. The recombinant protein is ahomopentamer of 17-kDa subunits with an apparent molecular mass of 87 kDa as determined by sedimentation equilibriumcentrifugation (it sediments at an apparent velocity of 5.0 S at 20°C). The protein has been crystallized in space group C2221 .
8p
research12
23-04-2013
26
1
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Duckd2-crystallin is a soluble tetrameric lens protein. In the presence of guanidinium hydrochloride (GdnHCl),it undergoes stepwise dissociation and unfolding. Gel-filtra-tion chromatography and sedimentation velocity analysis has demonstrated the dissociation of the tetramer protein to a monomeric intermediate with a dissociation constant of 0.34lM 3 . Dimers were also detected during the dissociation and refoldingprocesses.
8p
tumor12
20-04-2013
32
1
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Apart from the multiple alignment construction problem, a fully automatic approach also has to provide a clustering, and to work for multidomain proteins, define domain boundaries. For instance, the Domainer algorithm, 10 which performs the clus- tering of domain families based on all versus all Blastp matching, is a fully automatic approach that was used for building the ProDom database. We are most familiar with the Domainer method but believe that other automated sequence clustering approaches share similar drawbacks.
8p
yasuyidol
02-04-2013
37
3
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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: C-reactive protein velocity to distinguish febrile bacterial infections from non-bacterial febrile illnesses in the emergency department...
8p
thulanh18
28-10-2011
46
1
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