Radical product

This thesis documents a research program in which Australian grown Danshen extracts and related bioactive compounds have been demonstrated to be effective in scavenging free radicals, namely ROS generation, in a cell free system and NADPH oxidase derived superoxide (O2-) generation in vascular tissue (rat aorta). Danshen extracts, both aqueous and ethanol, and their active compounds (Tanshinone IIA, Salvianolic Acid B and Danshensu) demonstrated anti-oxidant activity however findings exhibited stronger activity in a cell free system than in the aortic vascular tissue.

138p runthenight07 01-03-2023 11 3   Download

The primary objective of the current study is to investigate the role of innovation in supply chain management. By using the cross-sectional research design, 300 questionnaires were distributed among the employees of logistic companies.

12p tocectocec 24-05-2020 40 1   Download

Glyoxal is a key compound involved in glyoxal oxidase (GLOX)-dependent production of glyoxylate, oxalate and H2O2 by lignin-degrading basidiomycetes. In this paper, we report that glyoxal was produced from a metabolite of ligninolytic fungi, linoleic acid, by manganese peroxidase (MnP)-dependent lipid peroxidation. In the absence of the parent substrate of linoleic acid, the dialdehyde was oxidized by MnP and Mn(III) chelate to start free radical reactions with emission of chemiluminescence at 700– 710 nm. ...

9p system191 01-06-2013 69 7   Download

Self-regulation of the 2-oxo acid dehydrogenase complexes during catalysiswas studied.Radical species as sideproducts of catalysis were detected by spin trapping, lucigenin fluor-escence and ferricytochromec reduction. Studies of the complexes after converting the bound lipoate or FAD cofactors tononfunctional derivatives indicated that radicals are generated viaFAD. In the presence of oxygen, the 2-oxo acid, CoA-dependent production of the superoxide anion radical was detected.

12p tumor12 22-04-2013 38 3   Download

Oxidative stress and imbalance between free radical generation and detoxi-fication may play a pivotal role in the pathogenesis of Leber’s hereditary optic neuropathy (LHON). Mitochondria, carrying the homoplasmic 11778⁄ND4, 3460⁄ND1 and 14484⁄ND6 mtDNA point mutations associ-ated with LHON, were used to generate osteosarcoma-derived cybrids. Enhanced mitochondrial production of reactive oxygen species has recently been demonstrated in these cybrids [Beretta S, Mattavelli L, Sala G, Trem-olizzo L, Schapira AHV, Martinuzzi A, Carelli V & Ferrarese C (2004) Brain127, 2183–2192]. ...

0p awards 05-04-2013 45 4   Download

Cytochrome P450 enzymes promote a number of oxidative biotransformations including the hydroxylation of unacti-vated hydrocarbons.

26p awards 05-04-2013 44 7   Download

Quantitation of superoxide radical (O2 – Æ) production at the site of radical generation remains challenging. A simple method to detect nanomolar to micromolar levels of superoxide radical in aqueous solution has been devel-oped and optimized. This method is based on the efficient trapping of O2 – Æ using a novel fluorescent probe (2-chloro-1,3-dibenzothiazolinecyclohex-ene), coupled with a spectra character-signaling increase event.

9p galaxyss3 21-03-2013 43 3   Download

COMPETITIVE RESPONSE TO RADICAL PRODUCT INNOVATIONS The competitive case serves as a baseline, but it is not a realistic description of choice in the presence of peer group externalities. I next consider a market with ten equally-sized districts, a degree of Tiebout choice that, as is discussed below in Section 1.4, corresponds roughly to the 80th percentile U.S. metropolitan area. Assume that J = 10 , n = N 10 , and 10 j μ j = , j = 1,K,10 . Panel C of Figure 1.1 displays the unique, perfectly sorted equilibrium when δ = 0 . Families in the j th decile of the income...

76p mualan_mualan 25-02-2013 50 8   Download

Ig-like transcript 2 (ILT2) is a suppressive receptor that participates in the control of the autoimmune reactivity. This action is usually carried out in a proinflammatory microenvironment where there is a high production of free radicals and NO.

11p vinaphone15 25-02-2013 37 2   Download

Tham khảo luận văn - đề án 'báo cáo y học: " leukocyte oxygen radical production determines disease severity in the recurrent guillain-barré syndrome"', luận văn - báo cáo phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

6p thulanh27 12-12-2011 55 4   Download

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome...

6p thulanh26 09-12-2011 49 4   Download

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: NADPH-oxidase-driven oxygen radical production determines chondrocyte death and partly regulates metalloproteinase-mediated cartilage matrix degradation during interferon-γ-stimulated immune complex arthritis...

11p thulanh12 13-10-2011 35 3   Download

The annual production of various polymers can be measured only in billion tons of which polyolefins alone figure around 100 million tons per year. In addition to radical and ionic polymerization, a large part of this huge amount is manufactured by coordination polymerization technology. The most important Ziegler-Natta, chromium- and metallocene-based catalysts, however, contain early transition metals which are too oxophilic to be used in aqueous media.

19p boyminsk 10-06-2010 153 16   Download