intTypePromotion=1
zunia.vn Tuyển sinh 2024 dành cho Gen-Z zunia.vn zunia.vn
ADSENSE

Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

Chia sẻ: Nguyen Thang | Ngày: | Loại File: PDF | Số trang:12

37
lượt xem
3
download
 
  Download Vui lòng tải xuống để xem tài liệu đầy đủ

Self-regulation of the 2-oxo acid dehydrogenase complexes during catalysiswas studied.Radical species as sideproducts of catalysis were detected by spin trapping, lucigenin fluor-escence and ferricytochromec reduction. Studies of the complexes after converting the bound lipoate or FAD cofactors tononfunctional derivatives indicated that radicals are generated viaFAD. In the presence of oxygen, the 2-oxo acid, CoA-dependent production of the superoxide anion radical was detected.

Chủ đề:
Lưu

Nội dung Text: Báo cáo Y học: Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

ADSENSE

CÓ THỂ BẠN MUỐN DOWNLOAD

 

Đồng bộ tài khoản
2=>2