Refinements

The alumina refining industry is one of a number of global industries that produce process waters containing mercury. The research program detailed in this dissertation focuses on processes for removing mercury from Bayer digestion condensate streams. Bayer refinery digestion condensate is chemically unique because it exhibits high pH and is chemically reducing, thermodynamically favouring the presence of elemental mercury.

192p runthenight05 01-03-2023 5 3   Download

This research develops a rich theoretical and empirical understanding of embeddedness by way of three dimensions (structural, relational and cultural), and investigates its implications for actors’ value co-creation behaviours and value-in-context outcomes. In addition, the research refines co-creation perspectives by examining a central boundary condition of co-creation processes. The data was collected in an online service environment and was analysed using structural equation modelling techniques.

183p runthenight04 02-02-2023 9 2   Download

The aims of this thesis are informed by the limitations of existing research identified above. The overall objective of the thesis is to develop and test a framework of accountant identities (accountant subtypes) inferred from stereotypical perceptions and to identify the attributes that underlie the subtypes. The initial construction of the framework is based on the accountant stereotypes identified in existing research. The framework is constructed from two dimensions based on role (tasks performed by accountants) and character (perceived personality traits).

240p runthenight04 02-02-2023 5 2   Download

The current study reviews the analysis on directions in research on QWL (Quality of Work Life) as uncertain organizational designs, expanded learning and specialization, interdisciplinary collusion, elevation of technology and profession, current health complications and refinement in medical education have a number to play.

9p guineverehuynh 22-06-2020 31 0   Download

Mark the letter A, B, C or D on your answer sheet to indicate the word that differs from the rest in the position of the main stress in each of the following questions. 1. A. symbolic B. internal C. dimension D. habitat 2. A. hygiene B. shampoo C. refine D. transmit 3. A. merchandise B. prosperous C. tolerant D. musician 4. A. generate B. encourage C. perspective D. affection 5. A. summertime B. vigorous C. consensus D. populate

8p maidung2106 25-06-2013 235 19   Download

The currently accepted model of moult control in crusta-ceans relies entirely on the hypothesis that moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) repress ecdysteroid synthesis of the target tissue (Y-organ) only during intermoult, and that changes in syn-thesis and/or release of these neurohormones are central to moult control.

9p tumor12 20-04-2013 52 3   Download

The high-resolution 3D structure of the octapeptide hor-mone angiotensin II (AII) in aqueous solution has been obtained bysimulated annealing calculations, using high-resolutionNMR-derived restraints. After final refinement in explicit water, a familyof 13 structures was obtained with a backbone RMSD of 0.73 ± 0.23 A˚ . AII adopts a fairly compact folded structure, with its C-terminus and N-ter-minus approaching towithin
7.2 A ˚ of eachother.

12p tumor12 20-04-2013 30 2   Download

The X-ray structure of mistletoe lectin I (MLI), a type-II ribosome-inactivatingprotein (RIP), cocrystallized with galactose is described. The model was refined at 3.0 A ˚ resolution to an R-factor of 19.9% using21 899 reflections, with Rfree 24.0%. MLI forms a homodimer (A–B)2in the crystal, as it does in solution at high concentration. The dimer is formed through contacts between the N-terminal domains of two B-chains involvingweak polar and non-polar interactions.

11p fptmusic 16-04-2013 43 3   Download

The three-dimensional crystal structure of recombinant annexin Gh1 fromGossypium hirsutum(cotton fibre) has been determined and refined to the finalR-factor of 0.219 at the resolution of 2.1 A ˚ . This plant annexin consists of the typical
annexin fold and is similar to the previously solved bell pepper annexinAnx24(Ca32), but significant differences are seen when compared to the structure of nonplant annexins.

8p fptmusic 16-04-2013 39 2   Download

Starting with oligopeptide sequences and using PCR, the gene of the cyclodextrinase fromFlavobacteriumsp. no. 92 wasderivedfrom thegenomicDNA.Thegenewas sequenced and expressed inEscherichia coli; the gene pro-duct was purified and crystallized. An X-ray diffraction analysis using seleno-methionines with multiwavelength anomalous diffraction techniques yielded the refined 3D structure at 2.1 A ˚ resolution.

10p fptmusic 16-04-2013 33 4   Download

Conformational analysis of angiotensin I (AI) and II (AII) peptides has been performed through 2D 1 H-NMRspectro-scopy in dimethylsulfoxide and 2,2,2-trifluoroethanol/H2 O. The solution structural models of AI and AII have been determined in dimethylsulfoxide using NOE distance and 3 JHNHacoupling constants. Finally, theAI family of models resulting from restrained energy minimization (REM) refinement, exhibits pairwise rmsd values for the family ensemble 0.26 ± 0.13 A ˚,1.05 ± 0.23 A ˚, for backbone and heavy atoms, respectively, and the distance penalty function is calculated at 0.

11p fptmusic 16-04-2013 55 4   Download

HIV-1 protease (PR) and two drug-resistant variants – PR with the V82A mutation (PRV82A) and PR with the I84V mutation (PRI84V) – were studied using reduced peptide analogs of five natural cleavage sites (CA-p2, p2-NC, p6 pol -PR, p1-p6 and NC-p1) to understand the structural and kine-tic changes. The common drug-resistant mutations V82A and I84V alter residues forming the substrate-binding site. Eight crystal structures were refined at resolutions of 1.10–1.60 A ˚ .

13p fptmusic 12-04-2013 38 2   Download

The structure of the complex between the minor groove binder netropsin and d(GGCCAATTGG) was determined via single-crystal X-ray tech-niques. The structure was refined to completion usingrefmac5.1.24, result-ing in a residual R-factor of 20.0% (including 68 water molecules). Using crystal engineering and cryocooling techniques, the resolution could be enhanced to 1.75 A ˚ , resulting in an unambiguous determination of the drug conformation and orientation.

11p fptmusic 11-04-2013 34 2   Download

The crystal structure of a subtilisin-like serine proteinase from the psychro-trophic marine bacterium, Vibriosp. PA-44, was solved by means of molecular replacement and refined at 1.84 A˚ . This is the first structure of a cold-adapted subtilase to be determined and its elucidation facilitates examination of the molecular principles underlying temperature adaptation in enzymes.

14p awards 05-04-2013 37 1   Download

The crystal structure of the complex between human immunodeficiency virus type 1 (HIV-1) protease and a peptidomimetic inhibitor of ethyleneamine type has been refined toRfactor of 0.178 with diffraction limit 2.5 A ˚ .The peptidomimetic inhibitor Boc-Phe-Y[CH2CH2 NH]-Phe-Glu-Phe-NH2 (denoted here as OE) contains the ethylene-amine replacement of the scissilepeptidebond. The inhibitor lacks the hydroxyl group which is believed to mimic tetra-hedral transition state of proteolytic reaction and thus is suspected to be necessary for good properties of peptido-mimetic HIV-1 protease inhibitors.

11p awards 05-04-2013 38 4   Download

A phylogenetic analysis of more than 350 multicopper oxidases (MCOs) from fungi, insects, plants, and bacteria provided the basis for a refined classification of this enzyme family into laccasessensu stricto (basidiomyc-etous and ascomycetous), insect laccases, fungal pigment MCOs, fungal ferroxidases, ascorbate oxidases, plant laccase-like MCOs, and bilirubin oxidases.

19p inspiron33 26-03-2013 52 4   Download

The homodimeric 2C-methyl-d-erythritol 4-phosphate cytidylyltransferase contributes to the nonmevalonate pathway of isoprenoid biosynthesis. The crystal structure of the catalytic domain of the recombinant enzyme derived from the plant Arabidopsis thalianahas been solved by molecular replace-ment and refined to 2.0 A˚ resolution.

9p inspiron33 26-03-2013 35 5   Download

Brassica junceachitinase is an endo-acting, pathogenesis-related protein that is classified into glycoside hydrolase family 19, with highest homology (50–60%) in its catalytic domain to class I plant chitinases. Here we report X-ray structures of the chitinase catalytic domain from wild-type (apo,as well as with chloride ions bound) and a Glu234Ala mutant enzyme, solved by molecular replacement and refined at 1.53, 1.8 and 1.7 A˚ resolution, respectively.

9p galaxyss3 19-03-2013 39 3   Download

A tri-functional monomeric primase–polymerase domain encoded by the plasmid pIT3 fromSulfolobus solfataricusstrain IT3 was identified using a structural–functional approach. The N-terminal domain of the pIT3 repli-cation protein encompassing residues 31–245 (i.e. Rep245) was modeled onto the crystallographic structure of the bifunctional primase–polymerase domain of the archaeal plasmid pRN1 and refined by molecular dynamics in solution.

14p galaxyss3 07-03-2013 36 3   Download

In this study, the crystal structure of a class Cb-lactamase from a psychro-philic organism,Pseudomonas fluorescens, has been refined to 2.2 A ˚ resolu-tion. It is one of the few solved crystal structures of psychrophilic proteins. The structure was compared with those of homologous mesophilic enzymes and of another, modeled, psychrophilic protein.

11p media19 06-03-2013 34 3   Download