Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131
30
lượt xem 2
download
lượt xem 2
download
Download
Vui lòng tải xuống để xem tài liệu đầy đủ
The high-resolution 3D structure of the octapeptide hor-mone angiotensin II (AII) in aqueous solution has been obtained bysimulated annealing calculations, using high-resolutionNMR-derived restraints. After final refinement in explicit water, a familyof 13 structures was obtained with a backbone RMSD of 0.73 ± 0.23 A˚ . AII adopts a fairly compact folded structure, with its C-terminus and N-ter-minus approaching towithin7.2 A ˚ of eachother.
Chủ đề:
Bình luận(0) Đăng nhập để gửi bình luận!
CÓ THỂ BẠN MUỐN DOWNLOAD