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Representative protein
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Ebook "Endosomes" represent a fascinating interconnected network of thousands of vesicles that transport various cargoes, mainly proteins and lipids, to distant cellular destinations. How endosomes function, what coordinates the molecular determinants at each step of their dynamic life cycle and what their biological and medical relevance is, are among the questions addressed in this book.
167p
ladongphongthanh1008
22-04-2024
2
2
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Ebook "Current topics in complement II" to discuss recent advances in this rapidly-evolving field. This volume represents a collection of topics on the “novel” functions of complement, pathophysiology, protein structures, and complement therapeutics discussed during the conference.
333p
ladongphongthanh1008
22-04-2024
3
1
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Heat shock proteins (HSPs), a representative family of chaperone genes, play crucial roles in malignant progression and are pursued as attractive anti-cancer therapeutic targets. Despite tremendous efforts to develop anti-cancer drugs based on HSPs, no HSP inhibitors have thus far reached the milestone of FDA approval.
16p
vibransone
28-03-2024
3
2
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Lymphoma represents a heterogeneous group of cancers affecting the lymphatic system, encompassing nonHodgkin lymphoma (NHL) and Hodgkin lymphoma (HL). The majority of NHL cases originate from B cells. HL is characterized by the presence of rare Hodgkin and Reed-Sternberg cells. Within the context of the inflammatory response, two SH2 domain-containing protein tyrosine phosphatases (SHPs), namely SHP-1 and SHP-2, serve as negative regulators.
6p
viellison
28-03-2024
2
2
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Ebook "Molecular mechanisms of exocytosis ((Molecular biology intelligence unit)" written by recognized experts in the field aims at clarifying for a non-specialist audience the role of the key players in the exocytotic process not only in neuronal and endocrine cells but also in a variety of other relevant cell systems. The book represents a unique collection of up-to-date reviews that will introduce researchers and students to the forefront of this rapidly moving and fascinating field.
186p
duongthandue0501
28-02-2024
2
1
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In ebook "Peptide and protein interaction with membrane systems: Applications to antimicrobial therapy and protein drug delivery" the study of peptide-membrane interactions has been carried out using model membranes. It has been shown, indeed, that peptides feature the same activity on these systems. The most common membrane model is represented by lipid vesicles (liposomes), a simple but realistic system for physical and chemical studies of a variety of phenomena.
147p
nhanphanguyet
28-01-2024
6
2
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Peripheral neuropathy caused by amyloidosis is one of the well-recognised sequelae of mutations in the transthyretin gene (TTR). This represents a rare but predictable iatrogenic side effects, and doctors should be aware of this eventuality occurring in a shorter time span than previously anticipated.
4p
vitiki
30-01-2024
4
2
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Ebook "The retinoblastoma protein" covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.
205p
lucchinguyen
28-12-2023
5
2
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Immune checkpoint inhibitors of programmed cell death protein 1 (PD-1) represent a signifcant break‑ through in treating head and neck squamous cell carcinoma (HNSCC), with long-lasting responses and prolonged survival observed in frst- and second-line therapy. However, this is observed in
9p
vileonardodavinci
23-12-2023
6
2
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"Chromatographic fingerprint analysis of herbal medicines: Thin-layer and high performance liquid chromatography of Chinese drugs (Vol.3)" of this manual provides an overview of the analytical investigation of 23 additional Chinese Herbal Drugs, which are most commonly used in Traditional Chinese Medicine. Together with Volumes I and II this current volume represents the most comprehensive overview to analytical studies of those herbal drugs. This volume 3 is divided into 2 parts, please refer to part 1!
145p
damtuyetha
16-02-2023
4
1
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In this Masters thesis computational modelling techniques were employed to investigate iron-free apo-Lactoferrin (apo-Lf) structural conformation changes in the presence of variant temperature and pH. These conditions represent the environment most milk protein goes through in food processing and the production of food products.
162p
runthenight04
02-02-2023
5
2
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Cervical cancer (CxCa) is preventable and treatable via vaccination and screening. Cervicovaginal fluid (CVF) represents the physiological components of the female genital tract. These components are suitable to be utilized for clinical purposes, therefore, making CVF a suitable material for disease screening approaches. Due to high false-negative result rates and low attendance of current expensive routine CxCa screening methods, it has become more important to develop a point-of-care (POC) screening method that every single woman could reach worldwide.
12p
lyhuyenthu
31-01-2023
2
2
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Erythropoietin receptor (EPOR) is a functional membrane-bound cytokine receptor. Erythropoietin (EPO) represents an important hematopoietic factor for production, maturation and differentiation of erythroid progenitors. In non-hematopoietic tissue, EPO/EPOR signalization could also play cytoprotective and antiapoptotic role.
9p
vihagrid
30-01-2023
7
3
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Indigenous domestic chicken represents a major source of protein for agricultural communities around the world. In the Middle East and Africa, they are adapted to hot dry and semi-dry areas, in contrast to their wild ancestor, the Red junglefowl, which lives in humid and sub-humid tropical areas.
16p
vihagrid
30-01-2023
10
3
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This study "Aquatic plants (Azolla filiculoides, Azolla pinnata, Landoltia punctata) and protists, thraustochytrids as renewable and sustainable sources of protein, phenolic, carotenoids and omega-3 fatty acids" provides important information on culturing Azolla (A. filiculoides and A. pinnata), duckweed (L. punctata) and thraustochytrids. It also represents a comprehensive analysis of two Azolla species (A. filiculoides and A. pinnata), one duckweed species (L. punctata) and two new thraustochytrids, all of which are capable of producing valuable biomolecules.
194p
runordie3
06-07-2022
5
1
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Radio-chemotherapy with 5-fluorouracil (5-FU) is the standard of care treatment for patients with colorectal can‑ cer, but it is only effective for a third of them. Despite our understanding of the mechanism of action of 5-FU, drug resistance remains a significant limitation to the clinical use of 5-FU, as both intrinsic and acquired chemoresistance represents the major obstacles for the success of 5-FU-based chemotherapy.
19p
vikolindagrabar
27-07-2022
5
1
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Although chondrosarcoma is the second most common primary malignant bone tumor, treatment options are limited due to its extensive resistance to a chemo- and radiation therapy. Since shikonin has shown potent anticancer activity in various types of cancer cells, it represents a promising compound for the development of a new therapeutic approach.
11p
vikolindagrabar
27-07-2022
5
1
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At this time, elimination diets followed by oral food challenges (OFCs) represent the “gold standard” for diagnosing skin-manifesting food allergies (FA) in dogs and cats. Regrettably, there is no clear consensus on how long one should wait for clinical signs to flare after an OFC before diagnosing or ruling-out a FA in a dog or a cat.
4p
vigandhi
23-02-2022
17
1
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The ocean microbiome represents one of the largest microbiomes and produces nearly half of the primary energy on the planet through photosynthesis or chemosynthesis. Using recent advances in marine genomics, we explore new applications of oceanic metagenomes for protein structure and function prediction.
14p
vielonmusk
30-01-2022
10
0
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Functions for RNA-binding proteins in orchestrating plant development and environmental responses are well established. However, the lack of a genome-wide view of their in vivo binding targets and binding landscapes represents a gap in understanding the mode of action of plant RNA-binding proteins.
22p
vialfrednobel
29-01-2022
16
0
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