Risk scores model
-
Several studies have proved that Polygenic Risk Score (PRS) is a potential candidate for realizing precision screening. The effectiveness of low-dose computed tomography (LDCT) screening for lung cancer has been proved to reduce lung cancer specific and overall mortality, but the cost-effectiveness of diverse screening strategies remained unclear.
12p vishanshan 27-06-2024 1 1 Download
-
Results regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are inconsistent due to the different genetic backgrounds of the populations studied. We aimed to identify single-nucleotide polymorphisms (SNPs) associated with EC among the Chinese population and to evaluate the performance of genetic and non-genetic factors in a risk model for developing EC.
10p vishanshan 27-06-2024 2 1 Download
-
This study sought to investigate the prognostic value of basement membrane (BM)-associated gene expressions in oral cancer. Methods We harvested and integrated data on BM-associated genes (BMGs), the oral cancer transcriptome, and clinical information from public repositories. After identifying differentially expressed BMGs, we used Cox and Lasso regression analyses to create a BMG-based risk score for overall survival at various intervals.
15p vikoch 27-06-2024 3 1 Download
-
The main research purpose of this article is to sort out consumer information without specific personal data and use the target company’s neural network risk control decision model which is based on the risk scoring trajectory. We find the main interpretation variables, and then verify the direction and extent of the target’s influence to verify empirical results and help the target company make a correct decision analysis on the credit applicants’ loans.
13p dathienlang1012 03-05-2024 2 0 Download
-
This study aimed to use single-cell RNA-seq (scRNA-seq) to discover marker genes in endothelial cells (ECs) and construct a prognostic model for glioblastoma multiforme (GBM) patients in combination with traditional high-throughput RNA sequencing (bulk RNA-seq).
17p vileonardodavinci 23-12-2023 6 2 Download
-
Osteosarcoma (OS) is the most common primary malignancy of bone tumors. More and more ARHGAP family genes have been confrmed are to the occurrence, development, and invasion of tumors. However, its signifcance in osteosarcoma remains unclear. In this study, we aimed to identify the relationship between ARHGAP family genes and prognosis in patients with OS.
22p vileonardodavinci 23-12-2023 4 2 Download
-
Continued part 1, part 2 of ebook "Corporate financial distress and bankruptcy: Predict and avoid bankruptcy, analyze and invest in distressed debt (3rd edition)" provides readers with contents including: techniques for the classification and prediction of corporate financial distress and their applications; corporate credit scoring–insolvency risk models; an emerging market credit scoring system for corporates; application of distress prediction models; estimating recovery rates on defaulted debt;...
124p mocthanhdao0210 20-11-2023 8 4 Download
-
This study aimed to get a deeper insight into new osteosarcoma (OS) signature based on bone morphogenetic proteins (BMPs)-related genes and to confirm the prognostic pattern to speculate on the overall survival among OS patients.
14p vischultz 20-10-2023 1 1 Download
-
This study aimed to evaluate the clinical significance of a novel systemic immune-inflammation score (SIIS) to predict oncological outcomes in upper urinary tract urothelial carcinoma(UTUC) after radical nephroureterectomy(RNU).
15p visharma 20-10-2023 2 2 Download
-
We used pyroptosis-related genes to establish a risk–score model for prognostic prediction of liver hepatocellular carcinoma (LIHC) patients. A total of 52 pyroptosis-associated genes were identifed. Then, data for 374 LIHC patients and 50 normal individuals were acquired from the TCGA database.
23p visharma 20-10-2023 4 2 Download
-
As available data increases, so does the opportunity to develop risk scores on more refined patient populations. In this paper we assessed the ability to derive a risk score for a patient no-showing to a clinic visit.
7p visteverogers 24-06-2023 2 2 Download
-
For the analysis of gene-environment (GxE) interactions commonly single nucleotide polymorphisms (SNPs) are used to characterize genetic susceptibility, an approach that mostly lacks power and has poor reproducibility. One promising approach to overcome this problem might be the use of weighted genetic risk scores (GRS), which are defined as weighted sums of risk alleles of gene variants. The gold-standard is to use external weights from published meta-analyses.
14p vinarcissa 21-03-2023 3 1 Download
-
Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNPs) as associated with colorectal cancer (CRC) risk in populations of European descent. However, their utility for predicting risk to CRC in Asians remains unknown.
7p vinarcissa 21-03-2023 7 2 Download
-
Part 1 of ebook "Credit risk management - Basic concepts: Financial risk components, rating analysis, models, economic and regulatory capital" provide readers with content about: bank risk management; credit scoring; credit ratings; risk modelling and measurement; scoring at different customer stages; data definition and collection;...
289p damtuyetha 16-02-2023 9 4 Download
-
We aimed to develop and validate a tool to identify which pregnant/lactating young South African women (≤24 years) are at risk of HIV infection. Data from three national South African Prevention of Mother-to-Child Transmission (PMTCT) evaluations were used to internally validate three HIV acquisition risk models for young postpartum women.
13p viferrari 28-11-2022 7 2 Download
-
To explore the association between waist circumference (WC), estimated cardiopulmonary function (eCRF), and cardiovascular disease (CVD) risk in southern Xinjiang. Update the Framingham model to make it more suitable for the southern Xinjiang population.
9p viferrari 29-10-2022 2 2 Download
-
The role of M0 macrophages and their related genes in the prognosis of hepatocellular carcinoma (HCC) remains poorly characterized. Methods: Multidimensional bioinformatic methods were used to construct a risk score model using M0 macrophage-related genes (M0RGs).
13p vikolindagrabar 27-07-2022 4 2 Download
-
Biochemical recurrence (BCR) after initial treatment, such as radical prostatectomy, is the most frequently adopted prognostic factor for patients who suffer from prostate cancer (PCa). In this study, we aimed to construct a prognostic model consisting of gene expression profiles to predict BCR-free survival.
11p viangelamerkel 27-07-2022 6 3 Download
-
The incidence of early-onset colorectal cancer (EOCRC) is increasing at an alarming rate and further studies are needed to identify risk factors and to develop prevention strategies.
10p vipriyankagandhi 27-07-2022 6 1 Download
-
Accurate identification of older persons at risk of unplanned hospital visits can facilitate preventive interventions. Several risk scores have been developed to identify older adults at risk of unplanned hospital visits.
9p vinobelprisen 26-03-2022 18 5 Download