Salicylic aldehyde

Bài giảng Thực hành Hóa hữu cơ 2 được biên soạn nhằm cung cấp cho sinh viên những nội dung, kiến thức để thực hiện các thí nghiệm định tính nhóm chức; định tính hợp chất tạp chức; tổng hợp acid acetyl salicylic (Aspirin); tổng hợp acetanilid; tổng hợp n-Butyl acetat; tổng hợp acid benzoic;... Mời các bạn cùng tham khảo chi tiết nội dung bài giảng!

12p loivokiet 06-06-2023 12 3   Download

The various organic acids have screened; like gallic acid, 4-hydroxy benzoic acid, 4-amino benzoic acid, phenylacetic acid, chloroacetic acid, sulfosalicylic acid, sulfanilic acid, chloro benzoic acid, phthalic acid, salicylic acid, cinnamic acid, hippuric acid, 1- naphthyl acetic acid, o-amino benzoic acid, p-TSA, succinic acid, malic acid, and among them sulfanilic acid is a suitable catalyst. The reaction condition was optimized with respect to the solvent, the amount of catalyst as well as the variation of the ketone, aldehyde, and amine substrates.

13p cothumenhmong11 06-05-2021 15 2   Download

In acetonitrile, the amine became a catalyst to form 6-bromo-3-(5-bromo-2-hydroxybenzyl)-2-phenyl-4Hchromen-4-one. Under microwave conditions, it took about 20 min to complete the reaction and gave the same yields as theconventional method. Structures of these compounds were firm with NMR, MS spectra.

6p tamynhan5 10-12-2020 10 2   Download

Salicylic aldehyde-N(4)-(4-ethoxyanilinyl)thiosemicarbazone (H2L) was synthesized by condensation between salicylic aldehyde (SA) and N(4)-(4-ethoxyanilinyl)thiosemicarbazide (TSCZ) in presence of glacial acetic acid as a homogeneous catalyst in ethanol. As a result of analysis by the surface response based on Box – Hunter model with the confidence level of 95%, the expectable yield reached the highest point (around 68%) at 80oC for 10 minutes when approximately 1 mole of SA reacted to equivalently 1 mole of TSCZ.

11p vithomasedison2711 15-08-2019 29 0   Download