Sensitivity

Graft copolymers based on carboxymethylcellulose (CMC) and thermosensitive polyetheramines (ethylene oxide/propylene oxide = 33/10 and 1/9) were prepared in water, at room temperature, by using a carbodiimide and N-hydroxysuccinimide as activators. SLS was applied to obtain Mw, A2 and Rg of CMC and its derivatives.

10p vihermione 06-01-2023 2 1   Download

The influence of Na2SO4 as a kosmotropic salt on the thermogelation of xyloglucan (XG) solutions was measured by rheology. The gelation occurred at lower temperatures and shorter times when the salt concentration was increased above 0.5 mol.L−1. For Na2SO4 concentrations equal to 1 mol.L−1, a not thermoreversible elastic hydrogel was obtained.

10p vihermione 06-01-2023 2 1   Download

The interaction between small molecules and neutral soluble dietary fiber is one of the proposed mechanisms determining the bioavailability of these components in the small intestine. However, the weak nature of these interactions makes it difficult to find an analytical method sensitive enough to detect them.

11p viginny 30-12-2022 3 1   Download

This study focuses on the production and characterization of electrosprayed cashew gum (CG) microparticles that encapsulate β-carotene. CG is an inexpensive, non-toxic polysaccharide obtained from Anacardium occidentale trees.

10p viginny 30-12-2022 7 2   Download

Bài viết "Một cách tiếp cận mới để ẩn hoàn toàn các luật kết hợp nhạy cảm" đề xuất một cải thiện của thuật toán IFHSAR (Improve fast hiding sensitive association rules). Thuật toán đề xuất mới NIFHSAR là phiên bản cải tiến tiếp theo của thuật toán IFHSAR. Thuật toán NIFHSAR mới vừa có thể ẩn hoàn toàn các luật SAR đã cho, và còn giảm thiểu việc mất luật so với thuật toán ban đầu. Các kết quả thực nghiệm cho thấy đề xuất của chúng tôi giảm thiểu được việc mất các luật không nhạy cảm so với thuật toán IFHSAR trong hầu hết các trường hợp thử nghiệm.

7p lieuyeuyeu18 23-12-2022 10 1   Download

A sensitive and accurate method for the quantification of 1 -Demethyl-1 -nitrosonicotine (NNN) and 4-(methylnitrosamino)-1-(3-Pyridyl)-1-butanone (NNK) in indoor air was developed and validated. To this aim, a novel approach for the collection of two tobacco-specific nitrosamines, using silica sorbent cartridges followed by simplified sample preparation and isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry, was applied.

10p viginny 23-12-2022 2 2   Download

The sensitivity of an active fast neutron assay system for the measurement of 235U enrichment in small samples of low-enriched triuranium octoxide (U3O8) is described. The system comprises four organic liquid scintillation detectors in a polyethylene container in which a stimulating americium-lithium neutron source is placed below the sample to be interrogated.

8p vironald 15-12-2022 5 2   Download

In the present study, we describe the development of a fast, 2-step salt gradient for analysis of chondroitin sulfate disaccharides. Using salt gradients, which is somewhat unusual in HILIC-based separations, provides relatively fast chromatography with excellent sensitivity (15 min cycle time, 10–20 fmol/μL detection, 30–50 fmol/μL quantitation limit), and good linearity

6p viginny 23-12-2022 7 2   Download

A sensitive multiresidue method was developed to quantify 35 pharmaceuticals and 28 metabolites/transformation products (TPs) in fish liver, fish fillet and fish plasma via LC-MS/MS. The method was designed to cover a broad range of substance polarities.

13p viginny 23-12-2022 3 2   Download

Quantitative analysis of glycans released from glycoproteins using high-performance liquid chromatography (HPLC) requires fluorescent tag labeling to enhance sensitivity and selectivity. However, the methods required to remove large amounts of excess labeling reagents from the reaction mixture are timeconsuming.

9p viginny 23-12-2022 3 1   Download

The manufacturability of therapeutic monoclonal antibodies is limited by the harsh conditions that antibodies are subjected to during the purification procedure, which in turn restricts the development of novel acid-sensitive antibodies.

8p viginny 23-12-2022 5 2   Download

Liquid Chromatography tandem mass spectrometry (LC-MS/MS) is the gold-standard approach for androgen analysis in biological fluids, superseding immunoassays in selectivity, particularly at low concentrations. While LC-MS/MS is established for analysis of testosterone and androstenedione, 5αdihydrotestosterone (DHT) presents greater analytical challenges.

12p viginny 23-12-2022 5 2   Download

The development and optimization of cell culture media for biotech applications is a fundamental step of process development. The composition of cell culture media requires an ideal blend of amino acids, vitamins, nucleosides, lipids, carbohydrates, trace elements and other components.

7p viginny 23-12-2022 5 1   Download

The inefficiency of wastewater treatment plants (WWTPs) to remove contaminants of emerging concern (CECs) leads to their continuous release to the environment. Consequently, CECs are present at low concentrations in the treated wastewater (TWW), producing unpredicted and unwanted effects on living organisms as they are discharged into water receiving bodies.

12p viginny 23-12-2022 4 2   Download

The presence of antibiotics in the aquatic environment is becoming one of the main research focus of scientists and policy makers. Proof of that is the inclusion of four antibiotics, amongst which is amoxicillin, in the EU Watch List (WL) (Decision 2020/1161/EU)) of substances for water monitoring. xicillin in water at the sub-ppb levels required by the WL is troublesome due to its physicochemical properties.

10p viginny 23-12-2022 6 2   Download

Monoclonal antibodies (mAb) are used as therapeutics and for diagnostics of a variety of diseases, and novel antibodies are continuously being developed to find treatments for new diseases. Therefore, the manufacturing process must accommodate a range of mAb characteristics. Acid-sensitive mAbs can severely compromise product purity and yield in the purification process due to the potential formation of aggregates.

8p viginny 23-12-2022 8 2   Download

The use of hybrid surface technology (HST), applied to the metal surfaces of an ACQUITYTM UPLCTM system and column, designed to mitigate the chelation, poor peak shape and analyte loss seen with acidic phospholipids was investigated.

7p viginny 23-12-2022 5 2   Download

In this paper, we present a reduced-order modeling approach to study the Molten Salt Fast Reactor (MSFR). Our approach is nonintrusive and based on the proper orthogonal decomposition method. We include adaptivity in selecting the sampling points both in time and parameter space. Steady-state and transient analysis were both performed using the developed models.

14p vironald 15-12-2022 4 1   Download

Neutron noise calculated from the neutron noise equation in the frequency domain is governed by the cross section and kinetic parameters. Deterministic and stochastic methods to obtain the sensitivity coefficient of neutron noise with respect to the abovementioned parameters are proposed.

6p vironald 15-12-2022 4 1   Download

The present paper is concerned with the validation of the Corium jet fragmentation model ofASTEC v2.0 rev3 by means of a selection of six experiments carried out within the FARO facility. The different conditions applied within these six experiments help to analyse the model behaviour in different situations and to expose model limits. In addition to comparing model outputs with experimental measurements, sensitivity analyses are applied to investigate the model.

7p vironald 15-12-2022 3 1   Download