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Serum resistance
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Biliary tract cancer (BTC) is a relatively rare but aggressive gastrointestinal cancer with a high mortality rate. Cancer stem cell (CSC) populations play crucial roles in tumor biology and are responsible for the low response to anti-cancer treatment and the high recurrence rate. This study investigated the role of Transgelin-2 (TAGLN2), overexpressed in CSC in BTC cells, and analyzed its expression in patient tissues and serum to identify potential new targets for BTC.
15p
vishanshan
27-06-2024
1
1
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To determine serum leptin levels and its correlation with prepregnancy BMI, BMI, and insulin resistance at 24 - 28 weeks of gestation and before delivery in subjects with gestational diabetes mellitus (GDM).
12p
vijaychest
16-05-2024
3
1
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Antibiotic-resistant Klebsiella pneumoniae are a major cause of hospital- and community-acquired infections, including sepsis, liver abscess, and pneumonia, driven mainly by the emergence of successful high-risk clonal lineages.
15p
vibransone
28-03-2024
1
1
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To assess insulin resistance by HOMA-IR and serum human placental lactogen (hPL) level and the relationship between these factors and risk factors of gestational diabetes mellitus (GDM). Subjects and methods: A descriptive, cross-sectional study on 252 pregnant women with GDM and 48 pregnant women without GDM (non-GDM) from 7/2018 to 1/2022 at the National Hospital of Endocrinology.
10p
viangelamerkel
18-07-2022
8
2
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Resistance training has been recommended as an effective measure against age-related loss of muscle mass and muscle strength, called sarcopenia, even in older adults. However, despite subjecting each participant to the same training program, the training effect solely depended on the individual.
9p
vinobelprisen
26-03-2022
19
4
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Obesity is associated with insulin resistance (IR) and considered a risk factor for diabetes mellitus (DM) in cats. It has been proposed that homeostasis model assessment (HOMA-IR), which is the product of fasting serum insulin (mU/L) and glucose (mmol/L) divided by 22.5, can be used to indicate IR.
10p
vidarwin
23-02-2022
8
1
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The excessive use of antibiotics in the livestock feed industry caused inevitable side effects of microbial resistance. Besides this residual antibiotics in animal-derived foodstuff imposed serious health problems for humans. So this study aimed to investigate the potential use of Bacillus velezensis to substitute antibiotics for poultry production.
8p
vigandhi
23-02-2022
11
1
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This study aims to evaluate the role of the fibrinogen/albumin ratio (FAR) in predicting platinum resistance and survival outcomes of patients with ovarian clear cell carcinoma (OCCC). Methods: Coagulation function and D-dimer, serum albumin, CA125 and HE4 levels were measured before surgery in OCCC patients undergoing initial surgery in our institution.
10p
vielonmusk
21-01-2022
16
1
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The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been characterized. Here, we identify genes that contribute to growth of E. faecium in human serum through transcriptome profiling (RNA-seq) and a highthroughput transposon mutant library sequencing approach (Tn-seq).
12p
vilarryellison
29-10-2021
10
1
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Chronic systemic inflammatory syndrome has been implicated in the pathobiology of extrapulmonary manifestations of chronic obstructive pulmonary disease (COPD). We aimed to investigate which cell types within lung tissue are responsible for expressing major acute-phase reactants in COPD patients and disease-free (“resistant”) smokers.
9p
vimontana2711
05-04-2021
3
1
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Corticosteroids are widely used to control asthma symptoms, but steroid resistance (SR) is a common adverse reaction. Therefore, it is important to accurately predict the corticosteroid response of asthmatic patients.
7p
vimaine2711
26-03-2021
14
2
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Both gravitational loading and the forces generated by muscle contraction have direct effects on serum markers of bone metabolism. The object of this study was to examine the direct effects of a single session of resistance exercise or walking on biochemical markers of bone metabolism in participants with low bone mass.
8p
vioregon2711
22-02-2021
13
1
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This study has been under taken to know the virulence factors associated with E. coli causing Urinary Tract Infection (UTI) in comparison to intestinal commensal E. coli. Out of 600 UTI patients 100 had E. coli isolates which were studied for virulence factors. A total of 100 isolates of E coli from stool samples of apparently healthy individuals were included as controls.
7p
caygaocaolon8
07-11-2020
7
1
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In breast cancer, high levels of the inflammatory cytokine interleukin-6 (IL-6) have been associated with disease-free survival and treatment resistance. Increased serum levels of IL-6 have been correlated with increased levels of NF-κβ and aromatase expression in adipose tissue.
16p
vilisa271
22-09-2020
36
1
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Androgens drive the onset and progression of prostate cancer (PCa) via androgen receptor (AR) signalling. The principal treatment for PCa is androgen deprivation therapy, although the majority of patients eventually develop a lethal castrate-resistant form of the disease, where despite low serum testosterone levels AR signalling persists.
11p
vialabama2711
21-09-2020
20
0
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We hypothesized that pretreatment serum levels of insulin and other serum markers would predict Progression-free survival (PFS), defined as time to castration-resistant progression or death, in metastatic androgendependent prostate cancer (mADPC).
10p
vimale2711
25-08-2020
13
1
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Colorectal cancer is a major public health issue worldwide. Interleukin-17 (IL-17) and Th17 (T-helper cell type 17)-related molecules are involved in tumor development and in resistance to bevacizumab, an anti-vascular endothelial growth factor monoclonal antibody used in association with chemotherapy in metastatic colorectal cancer.
8p
vimale2711
21-08-2020
14
1
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Fibroblast growth factor 19 (FGF19), fibroblast growth factor 21 (FGF21) and Klotho are regulators of energy homeostasis. However, in the pediatric population, the relationships between obesity, metabolic disorders and the aforementioned factors have not been clearly investigated.
10p
vimanama2711
28-07-2020
9
1
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The aim of this study is to compare the levels of TNF-α in children with nephrotic syndrome and healthy control children and the correlation of TNF-α with clinical feature of NS. Fifty children with NS were divided into four groups: 14 steroid sensitive infrequent relapse (SSIFR), 12 steroid sensitive frequent relapse (SSFR), 9 steroid resistance (SR) and 15 newly diagnosis (ND) compared to twenty-five unrelated healthy children. The serum IL-13 levels for NS patients and healthy control children were measured by R&D quantitative ELISA kit.
7p
kethamoi5
03-06-2020
24
2
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Previous studies have established a correlation between vancomycin troughs and nephrotoxicity. However, data are currently lacking regarding the effect of guideline-recommended weight-based dosing on nephrotoxicity in methicillin-resistant Staphylococcus aureus bacteremia (MRSAB).
6p
vienzym2711
03-04-2020
8
1
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